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The FDA decision on Xywav in idiopathic hypersomnia is expected in the third quarter of 2021.

The current treatment landscape of polycycthemia vera (PV) hinges on treatments like hydroxyurea and ruxolitinib, the latter having emerged as an effective second-line therapy in patients with severe pruritis, symptomatic splenomegaly, or post-PV myelofibrosis symptoms.

The study findings show that atopic dermatitis is associated with internalizing and externalizing problems, with younger children experiencing emotional problems and adolescents with other atopic diseases having relationship problems.

According to the researchers, attempting to target the tumor microenvironment leads the way to an array of potential targetable pathways in the disease, including through the use of combination therapy.

Disproportionate rates of HIV and sexually transmitted infections (STIs) among Black women, who have a nearly 4 times higher enrollment rate in community supervision programs, underscores the need for culturally targeted HIV/STI interventions.

President Biden outlined new health initiatives in his first speech to a joint session of Congress; data show the disproportionate impact of air pollution on communities of color; COVID-19 case rates decline in half of US states.

Results of a longitudinal cohort study conducted in France suggest post-menopausal women who have a history of migraine may be at an increased risk of developing hypertension.

A proportion of rheumatoid arthritis pain may be more appropriately considered separate from inflammation and should be treated as a focus of its own.

Growth differentiation factor 11 (GDF11) may be a useful biomarker for predicting physical activity in patients with chronic obstructive pulmonary disease (COPD), which could help physicians better determine disease prognosis, investigators concluded.

Besides demonstrating noninferiority in objective response rates, zanubrutinib also showed a statistically significant lower risk of atrial fibrillation or flutter compared with ibrutinib.

An analysis by the Integrated Benefits Institute estimates that the total cost of lost time from work due to the COVID-19 pandemic could reach $50.5 billion, marking a 117% increase from prior projections.

A recent study concluded that designers of pulmonary rehabilitation programs should consider patients’ preferences on what components they feel are the most important to ensure that the programs are successful and effective.

All-cause graft failure in kidney transplant recipients with Fabry disease was about 30%, and improved when enzyme replacement therapy became available.

Posters from the Academy of Managed Care Pharmacy annual meeting evaluated real-world evidence on adherence to biosimilars and barriers to biosimilar adoption.

Patients with long COVID-19 at Veterans Health Administration facilities are being prescribed more addictive medications; indoor social distancing may provide a false sense of security; a drug for inflammatory bowel disease may blunt COVID-19 vaccine efficacy.

Right ventricular systolic function evaluated through VO2 max is a more accurate measure of functional capacity of persons with heart failure compared with left ventricular systolic function.

Researchers identified gene expression signatures associated with risk of type 1 diabetes (T1D).

Tuesday marked the first of 3 days of hearings on whether checkpoint inhibitors should keep indications after follow-up studies failed to show benefits that led to accelerated approval.

According to a poll conducted by Parkinson’s UK, issues such as walking, speaking, and balance and falls proved most significantly burdensome as the condition progresses, whereas tremor and psychological health becomes less important.

CDC updates mask guidelines for vaccinated and unvaccinated Americans.

Erin Jospe, MD, and Chris Gervais of Kyruus discuss how the company partners with health care organizations to help improve their COVID-19 vaccine rollout.

The United States will distribute 60 million doses of the AstraZeneca COVID-19 vaccine to other countries over the next several months; workplace safety rules on COVID-19 submitted by Labor Department for review; White House reportedly will not include measures targeting drug prices in antipoverty package.

A text message–based intervention successfully increased step counts for patients with pulmonary arterial hypertension (PAH).

Use of positive airway pressure therapy for obstructive sleep apnea was associated with a lower risk of developing Alzheimer disease, dementia, and mild cognitive impairment in older adults.

Quantifying the return on investment came up for both those implementing an oncology care pathway (as a potential barrier) as well as for payers still not convinced it is a way to go.

Findings from a new study out of Mount Sinai in New York show a small but rare chance of developing new-onset heart failure following hospitalization for COVID-19.

Skin cancer is one of the most common diseases dermatologists deal with on a daily basis, and as global rates increase, it is clear that climate change is a contributory factor, said Eva R. Parker, MD, FAAD, assistant professor of dermatology, Vanderbilt University Medical Center, during her session at the American Academy of Dermatology Virtual Meeting Experience.

Study results highlight the economic toll of migraine on employers in Japan.