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Sodium-glucose co-transporter 2 (SGLT2) inhibitors have been shown to both lower blood pressure and promote weight loss, and they act rather subtly, stated Rudolf de Boer, MD, PhD, clinical cardiologist and professor of translational cardiology, University Medical Center Groningen, the Netherlands.

The murine study, which assessed the combination of foretinib and an anti–PD-1 antibody, found that the regimen enhanced antitumor activity, offering promise in a cancer that has seen less success with immunotherapies than others.

Investigators identified serial liquid biopsy as an effective tool for identifying mutational changes of RAS genes in patients with metastatic colorectal cancer (mCRC) who have undergone antiangiogenic therapy.

New CDC data show an increase in some health care–associated infections during COVID-19.

Polypharmacy may be raising the risk of inappropriate medication use, and avoiding this is crucial.

It is the third set of warnings for certain Janus kinase (JAK) inhibitors due to the risk of heart attack or stroke, cancer, blood clots, and death.

Research shows how socioeconomic status can affect prognosis among patients with hepatocellular carcinoma (HCC).

Members of Congress ask the FDA for documents relating to Aduhelm's controversial approval; outside experts will advise the FDA on booster shots; nursing shortages intensify.

The product, lonapegsomatropin, is a sustained-release formulation and could replace daily injections.

Neal Dave, PharmD, the executive director of pharmacy at Texas Oncology, discussed physician anticipation for the first biosimilars for programmed death (PD)-1 inhibitors.

Even though respondents did not know very much about spinal muscular atrophy, the survey showed that most were in favor of newborn screening.

STEP findings build on those from the SPRINT trial, seemingly confirming that intensive treatment for hypertension can reduce the risk of serious adverse cardiovascular (CV) outcomes. However, there was no significant benefit toward risk for all-cause and CV-related mortality.

Native American and Black youth aged 10 to 19 years had the highest incidence of type 2 diabetes overall.

Many young people develop resistance to antiretroviral treatment or they experience lipoatrophy; many also have metabolic complications or inflammation via immune activation, noted Allison Agwu, MD, ScM, FAAP, FIDSA, Johns Hopkins University School of Medicine.

The study, using a BCR/ABL1 assay, found that the novel method is able to detect minimal residual disease (MRD) in a larger range of patients compared with quantitative real‐time polymerase chain reaction, the method currently used to detect MRD.

Findings of a recent review highlight the potential role nutrition can play in pediatric migraine.

Hilary Pinnock, MD, talks about what her session at the European Respiratory Society International Congress 2021 will cover and other sessions that she's excited to check out.

The approval of zanubrutinib makes it just the second therapy indicated for this rare type of lymphoma.

Tonya Winders, MBA, CEO and president of the Allergy & Asthma Network, highlights what she is looking forward to at the European Respiratory Society (ERS) International Congress 2021.

Findings indicate that youth with type 1 diabetes may benefit from limiting fat intake.

Highlighting the latest ophthalmology-related news reported across MJH Life Sciences™.

The Supreme Court rules to allow Texas to keep strict abortion law; the family behind Purdue Pharma has been granted immunity from future lawsuits related to the opioid crisis; Pfizer and Merck start trials for oral COVID-19 drugs.

Using whole genome sequencing, copy number signatures were successful in predicting both the presence of chromothripsis and clinical outcomes in patients with newly diagnosed multiple myeloma (MM).

The findings of this study suggest possible poor communication about human papillomavirus infection (HPV), the authors said, since they do not align with epidemiologic evidence.

By year 5 of therapy with disease-modifying anti-rheumatic drugs (DMARDs), only about one-third of patients with psoriatic arthritis (PsA) were expected to be continuing with their therapy.

Patients who have both multiple sclerosis (MS) and depression may have a higher risk of death and vascular disease compared with people who only have 1 or neither of those conditions.

People who suffered trauma as a child appear to be at a higher risk of fibromyalgia, although it is unclear exactly why.

Patients with systemic lupus erythematosus (SLE) said they still suffered significant pain and fatigue, even though they reported high rates of satisfaction with their therapies.