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The findings suggest that this new categorization of cognitive deficits in multiple sclerosis may support clinicians in treatment choices and help tailor cognitive rehabilitation strategies, the authors said.

An engineered lentivirus was created to avoid some of the drawbacks associated with current gene therapy vectors for sickle cell disease (SCD) and beta-thalassemia.

The authors said this study included more up-to-date definitions of diagnosing pulmonary arterial hypertension (PAH), which is an increasing factor in deaths from systemic sclerosis (SSc).

The novel, first-in-class, small molecule prompted high rates of clinical response and molecular remission in patients with oligoblastic acute myeloid leukemia (AML).

Study results published in PLoS One strongly suggest machine learning can be an effective approach to identify patients who should receive a diagnostic biochemical test to screen for acute hepatic porphyria.

A 4-biomarker panel can help ensure rheumatoid arthritis (RA) is accurately diagnosed, according to study results published in Arthritis Research & Therapy.

Johnson & Johnson, Novavax, release positive results from phase 3 trials on their respective coronavirus disease 2019 (COVID-19) vaccines; report indicates undercounted nursing home deaths in New York; experts push for improved mask practices.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

A recent survey found that patients experienced relief of certain motor and nonmotor symptoms of Parkinson disease from using cannabis.

Treatment optimization for heart failure with reduced ejection fraction is the focus of the American College of Cardiology’s 2021 update to its 2017 Expert Consensus Decision Pathway on managing patients with the condition.

Patients with symptomatic acute hepatic porphyria were found to be at greater risk of accessing long-term sick leave and disability pension compared with the general population, but were not shown to be at an increased overall risk of premature death.

The Biden administration will reopen the health exchanges created by the Affordable Care Act (ACA); direct HHS and other agencies to reexamine other health policies, including Medicaid work requirements; and reverse the so-called global gag rule while affirming support for reproductive health.

Results of a case-control study show metformin use may protect against the development of age-related macular degeneration (AMD) in adults 55 years and older, and the association is dose-dependent, with the greatest benefit at low to moderate doses.

Rates of coronavirus disease 2019 (COVID-19) cases decline in 41 states; Aetna to cover medically necessary breast augmentations for transgender individuals; Oklahoma seeks to return $2 million worth of hydroxychloroquine.

Secukinumab rarely leads to latent tuberculosis infection as a reported adverse event and is supported for use in treating chronic systemic inflammatory conditions.

Physicians can withdraw inhaled corticosteroids (ICS) from triplet therapy without increasing patients’ risk of chronic obstructive pulmonary disease (COPD)-related exacerbations.

A 13.9% increase in diagnosed cases of HIV was seen following expansion of Medicaid coverage under the Affordable Care Act.

While these therapies continue to revolutionize the treatment landscape of SMA, treatments are not without shortcomings or challenges.

A prospective cohort study found that diabetes and insulin resistance were the strongest risk factors for premature onset of coronary heart disease (CHD) among American women. Results were published in JAMA Cardiology.

Telemedicine sprang up very quickly and will stay around to some extent once the pandemic ends, said Peter McAllister, MD, a neurologist, board certified headache specialist, and medical director of the New England Institute for Neurology and Headache.

The Biden administration promises to increase vaccine delivery; the FDA issues an alert on alcohol-based hand sanitizers from Mexico; 3 pharma giants partner to speed EU vaccination efforts.

Higher mortality rates were seen among patients with acute lymphoblastic leukemia (ALL) who were considered obese, in a recent study of patients treated at Mayo Clinic.

Treatment with erenumab led to improvements in pain, medication use, and quality of life in onabotulinumtoxinA-resistant patients with chronic migraine, according to study results published in The Journal of Headache and Pain.

Changes in blood pressure, percentage of red blood cells, and serum cholesterol levels were found to occur in patients with Parkinson disease before the onset of motor symptoms, suggesting potential biomarkers for early diagnosis and treatment.

Periodic review of treatment safety and monitoring are necessary as medical centers increasingly use newer disease-modifying therapies earlier in the course of multiple sclerosis.

Women receiving treatment for early-stage breast cancer may have a lower risk of developing heart failure if their therapy regimens include statins.

President Joe Biden reportedly will take executive action to reopen federal marketplaces selling Affordable Care Act (ACA) health plans; Moderna investigating booster shot designed to be more effective against emerging variants of coronavirus disease 2019 (COVID-19); Brazil coronavirus variant is found in Minnesota.

Several factors will have a significant impact in the health care industry in 2021, such as management of disparities in vaccine administration and greater investment in telehealth, said Gurpreet Singh, MBA, US Health Services Leader at PwC.