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The KRAS mutation occurs in 13% of non–small cell lung cancers (NSCLC) and leads to worse outcomes in NSCLC.

The opportunity that precision medicine presents in the field of oncology will be further discussed during this year’s Patient-Centered Oncology Care® 2020 virtual meeting.

Aspirin is a known anti-inflammatory agent, but few studies have investigated its use among African American women to reduce the risk of breast cancer.

Researchers present a novel approach to identifying molecules associated with the progression of Parkinson disease and other neurodegenerative diseases.

Allison Brennan, MPP, discusses legislation that would affect accountable care organizations (ACOs), the impact coronavirus disease 2019 had on ACOs, and the fall National Association of ACOs meeting.

The CDC abruptly pulled guidance saying that COVID-19 is primarily spread via airborne transmission; HHS issues memo stating that the FDA no longer has the authority to sign any new rules on food, vaccines; a novel study examines risk of infection during a flight.

Pediatric patients who had a referral from their pediatric rheumatologist and continued insurance coverage saw decreased delays when transitioning to an adult rheumatology clinic.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

A new analysis of ADAURA data shows osimertinib cuts the risk of brain metastases or death by 82% compared with placebo in certain early-stage patients with NSCLC.

Differences in heart failure mortality over the previous 2 decades can partially be explained by social determinants of health prevalent in the patients’ counties.

Patients with advanced colon cancer who drank 4 or more cups of coffee a day had 36% improved survival odds.

Because men who have sex with men continue to represent a disproportionate number of annual HIV diagnoses each year, a recent study investigated the utility of remote testing and phone delivery of test results among the patient group.

A survey from the American College of Rheumatology (ACR) revealed that patients with rheumatic diseases are struggling to get access to health care treatment.

Researchers assess the psychosocial impact of allogeneic hematopoietic stem cell transplantation, particularly how preparing patients can assist in guiding health care providers in offering better care.

Melissa L. Johnson, MD, associate director for lung cancer research at Sarah Cannon Research Institute and partner in Tennessee Oncology, speaks on changes necessitated by the coronavirus disease 2019 (COVID-19) pandemic and connecting virtually.

Impaired sleep was found to contribute to more emotional reactions by study participants to stressful events the next day, with a comparative indifference to positive events also reported.

Implementing a multidisciplinary discussion has positive implications for both the diagnosis and management of interstitial lung disease (ILD), according to study findings.

Jason Shafrin, PhD, serves as the vice president of Health Economics at PRECISIONheor, and Meena Venkatachalam, MSc, is the senior director of Health Economics at PRECISIONheor.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

Europe sees an increase in COVID-19 cases; CDC releases data on racial disparities in fetal deaths; an update to COVID-19 testing strategies skipped CDC internal review.

The research spotlights the diverse landscape of pediatric cancer types harboring 2 types of genomic alterations.

Although innovations in cancer treatment have driven down overall cancer death rates and increased the number of survivors living with cancer, that progress has not benefitted everyone with cancer equally.

This week, the top managed care news included the effects of wildfires and the pandemic on health; a conversation on Ochsner Health’s Connected Maternity Online Monitoring Program; a preview of discussions at Patient-Centered Oncology Care® 2020.

A higher volume of exercise training may improve glycemic control more in individuals with type 2 diabetes (T2D) compared with individuals who exercise less frequently, according to a stud in Medicine & Science in Sports & Exercise.

A new chimeric antigen receptor (CAR) T cell therapy may help curb the problem of frequent relapse in patients with relapsed/refractory B-cell acute lymphoblastic leukemia.

A study of patients with multiple myeloma in China found many do not have access to a caregiver and most have to travel to another city to receive treatment.

The American Journal of Managed Care® recently hosted a Peer Exchange that featured discussion among a panel of expert cardiologists and managed care decision makers regarding how cardiovascular outcome trial results are impacting the use of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in patients with heart failure and how these drugs are shaping heart failure outcomes for patients. Panelists were Nihar R. Desai, MD, MPH, assistant professor of medicine in the cardiovascular medicine section of the Yale School of Medicine and investigator in the Center for Outcomes Research and Evaluation in New Haven, Connecticut; Jaime Murillo, MD, national senior director of cardiology at UnitedHealthcare in Fort Lauderdale, Florida; and Steven Nissen, MD, chief academic officer of the Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute at the Cleveland Clinic in Cleveland, Ohio. The moderator was Neil B. Minkoff, MD, chief medical officer of Coeus Consulting Group in Sudbury, Massachusetts.

An editor from The American Journal of Managed Care® spoke with Darren K. McGuire, MD, MHSc, to discuss the impact of the results of cardiovascular outcome trials on the use of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in patients with heart failure in real-world clinical practice. McGuire is professor of medicine, director of the cardiology clinical trials unit, and director of the Parkland Hospital and Health System outpatient cardiology clinics at the University of Texas Southwestern Medical Center in Dallas.