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A study investigating the functional connectivity of the praxis network in patients in the early stages of Parkinson’s disease (PD) found that dopaminergic therapy may normalize praxis abilities and related praxis networks during the early stages of the disease by facilitating the propagation of long-term representations of object-related actions to motor execution areas.

The clinical significance of minimal residual disease (MRD) status was recently highlighted in The American Journal of Managed Care®’s Peer Exchange series “A Review of the Treatment for Multiple Myeloma.” During the series, key opinion leaders discussed the clinical implications and significance of MRD testing in patients with multiple myeloma.

The September issue of The American Journal of Managed Care® (AJMC®) featured research on federal healthcare reform that detailed innovative ideas in Medicare, Medicaid, and the Veterans Affairs health system. Here are 5 findings from research published in the issue.

This week, the top managed care news included a report showing the US uninsured rate rose in 2018; the Trump administration indicating it will ban all flavors of e-cigarettes except for tobacco; new research showing the prevalence of hemophilia is 3 times larger than originally believed.

As orphan drugs account for an increasing share of drugs approved, they are driving up the cost of drug launches and drug prices. In a new paper, America's Health Insurance Plans analyzes these rising costs and the use of orphan drugs and asserts that policy makers need to revisit the Orphan Drug Act.

The family that owns the drug company at the center of the nation’s opioid problem reached a tentative settlement with thousands of municipal governments and nearly 2 dozen states that sued the pharma industry for its role in creating the crisis; nearly 8 in 10 Americans back legislation to protect people from surprise medical bills; the water crisis in Flint, Michigan, was not only about lead in the water—it was also about a deadly outbreak of Legionnaires’ disease.

Juul is being investigated for making unauthorized safety claims, while the governor of New York proposes to ban flavored e-cigarettes; Sutter Health is being sued for its role in rising healthcare costs; a European doctor who uses telemedicine and internet prescribing to provide American women with mifepristone and misoprostol to induce abortion in the first trimester is suing the FDA.