Currently Viewing:
Newsroom
Currently Reading
Adherence to NCCN Breast Cancer Guidelines Improves Outcomes
October 06, 2018 – Samantha DiGrande
Patient Navigation Programs Need to Address Gender, Race in Breast Cancer, Study Says
September 29, 2018 – Allison Inserro
Lack of Discussion Around Cancer Treatment Costs Leads to Financial Toxicity
September 28, 2018 – Samantha DiGrande
5 Recent Updates to Cancer Clinical Guidelines
September 28, 2018 – Surabhi Dangi-Garimella, PhD
More Data Necessary to Determine Best Treatment Option in Basal Cell Carcinoma
September 21, 2018 – Samantha DiGrande
Are Integrated Practice Units Working in Breast Cancer Clinical Pathways?
September 18, 2018 – Allison Inserro
Twice-Yearly MRIs Superior at Finding Early Breast Cancer in High-Risk Women
September 17, 2018 – Allison Inserro
NCCN Working Group Policy Recommendations Address Changing Paradigms in Cancer Care
September 16, 2018 – Jaime Rosenberg
NCCN Report on CAR T-Cell Therapy, Recommendations for Future Use
September 14, 2018 – Samantha DiGrande

Adherence to NCCN Breast Cancer Guidelines Improves Outcomes

Samantha DiGrande
In a study presented at the American Society of Clinical Oncology Quality Care Symposium last month, researchers looked to assess the adherence to National Comprehensive Cancer Network (NCCN) guidelines in the neoadjuvant treatment of breast cancer and the impact on outcomes. 
In a study presented at the American Society of Clinical Oncology Quality Care Symposium last month, researchers looked to assess the adherence to National Comprehensive Cancer Network (NCCN) guidelines in the neoadjuvant treatment of breast cancer and the impact on outcomes. 

Raju Kumar Vaddepally, MBBS, MD, and fellow study authors screened patients who were treated with neoadjuvant chemotherapy at the Henry Ford Health System in Detroit, Michigan during 2015 to 2016. In total, 46 patients met the criteria of the study. 

 
Click here to read more about cancer clinical guidelines.
In order to evaluate adherence, the authors created 8 adherence categories per NCCN’s guidelines. Total adherence rate was calculated by dividing the number of categories for which they underwent intervention by the total number of eligible adherence categories. Additionally, rates of pathologic complete response and breast conservation surgery were calculated to measure the outcomes. 

In total, researchers enrolled 9 triple negative breast cancer, 28 human epidermal growth factor receptor 2 (HER2) positive, and 17 triple positive patients. The authors found that there was 100% adherence in categories such as appropriate pre-chemotherapy evaluation (n = 46), completeness of histopathology report (n = 46), use of anti-HER2 antibody drug in patients with HER2 positive breast cancer (n = 28), and adjuvant radiation therapy (n = 39). 

In other categories, adherence differed. Specifically, in genetic consult researchers found 70% adherence (n = 33), 69% (n = 32) in reconstructive surgery, and 65% (n = 46) in cancer distress screening performed. 

The study also found that the pathologic complete response rate was 39%, and the breast conservation surgery rate was 41%. Overall, the results showed that adherence to NCCN guidelines leads to improve outcomes. 

Going forward, the authors recommend that “to improve the quality of care, institutions should closely monitor the adherence to NCCN or other alternative national guidelines.”

Reference 

Kumar Vaddepally R. Institutional adherence to National Comprehensive Cancer Network guidelines in neoadjuvant treatment of breast cancer and its correlation to outcomes. Presented at the American Society of Clinical Oncology Quality Care Symposium, September 28-29, 2018; Phoenix, Arizona. AB47. meetinglibrary.asco.org/record/166668/abstract 


Related Articles

Small Benefit Seen in Adding Radiation to DCIS Plan for Breast Cancer
Twice-Yearly MRIs Superior at Finding Early Breast Cancer in High-Risk Women
Second Opinions Beneficial for Patients With Breast Cancer
Know the Risk: 5 Breast Cancer Risk Factors
 
Copyright AJMC 2006-2019 Clinical Care Targeted Communications Group, LLC. All Rights Reserved.
x
Welcome the the new and improved AJMC.com, the premier managed market network. Tell us about yourself so that we can serve you better.
Sign Up