The Untold Burden of Uncomplicated UTIs: Addressing Recurrence and Treatment Gaps

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Ryan Haumschild, PharmD, MS, MBA; Thomas M. Hooton, MD; Wendy Cheng, PhD, MPH; Debra Fromer, MD; and Katie S. Murray, DO, discuss how uncomplicated urinary tract infection (UTI) management is evolving through new antibiotics such as pivmecillinam, sulopenem etzadroxil/probenecid, and gepotidacin to address growing resistance issues while emphasizing personalized approaches, prevention strategies, antimicrobial stewardship, and the socioeconomic impact of treatment failures across diverse patient populations.

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