Opinion|Videos|April 4, 2025

Comparing Standard-of-Care Antibiotics for Uncomplicated UTIs

Panelists discuss how standard-of-care antibiotics for uncomplicated urinary tract infections (UTIs) show varying efficacy, with nitrofurantoin and fosfomycin demonstrating superior response rates (85%-95%) compared with trimethoprim/sulfamethoxazole (70%-80% due to increasing resistance) and first-generation cephalosporins (80%-90%), and how cost-effectiveness depends on local resistance patterns, patient adherence to dosing schedules, medication costs and insurance coverage, treatment duration, recurrence rates, comorbidities, and potential adverse effects requiring additional interventions.

Video content above is prompted by the following:

  • How do current standard-of-care antibiotics such as nitrofurantoin, trimethoprim/sulfamethoxazole, fosfomycin, and first-generation cephalosporins compare in terms of patient response rates for uncomplicated UTIs?
  • What factors may contribute to one drug being more cost-effective than another in specific patient populations?

Newsletter

Stay ahead of policy, cost, and value—subscribe to AJMC for expert insights at the intersection of clinical care and health economics.


Latest CME

Brand Logo

259 Prospect Plains Rd, Bldg H
Monroe, NJ 08831

609-716-7777

© 2025 MJH Life Sciences®

All rights reserved.

Secondary Brand Logo