Clinical

The first drug specifically to treat patients with Mycobacterium avium complex, a rare and chronic lung disease, has been approved by the FDA. Arikayce is also the first drug to be approved under the Limited Population Pathway for Antibacterial and Antifungal Drugs, established under the 21st Century Cures Act.

Antibiotic treatment may be a feasible alternative to surgery for uncomplicated acute appendicitis, according to findings from a 5-year observational follow-up study that compared appendectomy with antibiotic treatment.

In a review of sex hormones and their role in the development of multiple sclerosis (MS), Ysrraelit and Correale compiled multiple references to provide clinical details regarding hormones and their respective immunological mechanisms.

There are a growing number of diabetes therapies, which has led to the need to individualize choices based on patient profile, said Robert A. Gabbay, MD, PhD, FACP, senior vice president and chief medical officer of Joslin Diabetes Center.

Assessing a patient’s understanding of his or her own illness is important as cancer treatments become more and more complex, said Denalee O’Malley, PhD, LSW, instructor, Department of Family Medicine and Community Health, Rutgers Robert Wood Johnson Medical School.

Better care for high-need, high-cost patients will require targeted care delivery models based on integrated data networks that include clinical, genomic, and social information. Check out our website’s new table/figure pop-up feature! Click on the name of a table or figure in the text to see it in your browser.

Amgen has submitted a supplemental New Drug Application to the FDA to expand the prescribing information of carfilzomib (Kyprolis) to include a once-weekly dosing option in combination with dexamethasone for patients with relapsed or refractory multiple myeloma.

Fragility fractures are a serious complication of type 1 and type 2 diabetes, but many clinicians who treat patients with diabetes are not aware of the increased risk of these fractures.

A substantial number of prescribers did not regard nonselective beta blockers as contraindicated, suggesting the need for improvement programs that target the prescribers’ awareness and knowledge.

A new study aimed to assess the prevalence of allergic sensitization, asthma, eczema, and hay fever from infancy to adulthood, finding that patterns of atopic disorders vary throughout childhood.

Group 2 innate lymphoid cells, a rare form of lymphocyte that defend the body from pathogens, may have immune-regulatory functions in rheumatoid arthritis and play a key role in the development of inflammatory arthritis, according to immunologists at Friedrich-Alexander-Universität Erlangen-Nürnberg.

The first patient has been treated in a phase 2b dose-confirmation study of AMT-061, an investigational gene therapy for the treatment of patients with severe and moderately severe hemophilia B. Once the dosing of AMT-061 is confirmed, the safety and efficacy of the therapy will be evaluated in the global phase 3 HOPE-B clinical trial.