Clinical

The FDA said it had received 20 reports in the 15 months since the first of the SGLT2 inhibitor class was approved, and had continued to receive reports since that time. All drugs in the class were included in the safety communication.

The study, published in Cancer, found a 14% higher rate of obesity among childhood cancer survivors in their surveyed population, compared to the federal numbers.

Venous thromboembolism during or after recent hospitalization for medical illness contributes a substantial economic burden to society across all hospital and ambulatory care delivered.

In his own words, "The practice of evidence-based medicine means integrating individual clinical expertise with the best available external clinical evidence from systematic research."

The National Institute of Standards and Technology has released new reference standards that could help diagnostic laboratories standardize their equipment and software to reduce variability in genetic test results between laboratories.

If adopted, the active surveillance threshold would give physicians a tool in the management of men with localized prostate cancer and could spare many aggressive therapy or radiation and its side effects.

Raising awareness of the dangers of mouth and throat cancer increased the number of black men in some of Florida's poorest counties who sought screening for the first time, which could improve survival rates through early detection and treatment.

What one type 1 diabetic has learned from living and coping with diabetes for 42 years.

While the marketing of the first biosimilar to be approved in the US market, Zarxio, has been delayed due to a court order, the FDA is providing guidance to manufacturers to help them effectively navigate the process of product development.

Researchers from the University of Pennsylvania tested interventions on smokers who worked to quit either on their own or in teams, with different reward structures.

Yesterday, the American Society of Clinical Oncology (ASCO) lifted the embargo on nearly 5000 abstracts that will be presented at ASCO's 51st Annual Meeting to be held in Chicago, May 29-June 2. The results from a few of the studies were released via a presscast that saw participation by the chair of ASCO's clinical communications committee, the current ASCO president, and the ASCO president-elect.

The study, conducted by the Global eHealth Unit at the Imperial College London, has found that the majority of insulin dosing apps are unreliable and put patients at risk of getting incorrect doses of insulin. Does this demand an FDA oversight of the apps?

The prices for new hepatitis C and cancer treatments are driving the cost of prescription drugs to new highs for more Americans, according to a new report, which found that 9 of 10 patients with drug costs of $50,000 or more used specialty drugs.

If all 12.7 million US youth with obesity become obese adults, the individual cost on average is just over $92,000, and the societal costs over their lifetimes may exceed $1.1 trillion, according to findings from the Brookings Institute.

A study published in the Journal of Surgical Research has found that surgeons are focusing on life-enhancing procedures for late-stage cancer patients. In their follow-up on 22,000 late-stage cancer patients in the United States between 2006 and 2010, while the use of surgeries declined only slightly, doctors became more likely to restrict surgery to healthier patients.

The diagnostic test, developed by Biodesix, Inc, will help guide treatment decisions in patients with advanced lung cancer.

The "digital phenotype," a catch-all term for the trail of relevant health data people leave behind in their interactions with the internet, social media, and technology, has largely untapped potential for the early detection of various conditions.

The database will allow consumers, healthcare providers, and product manufacturers to access information tracked on medical devices, with the end goal of improving patient safety, improving device postmarket surveillance, and facilitating medical device innovation.

While West Africa is on its way to be nearly Ebola-free, Dr Marie-Paule Kieny, assistant director-general for Health Systems and Innovation with the World Health Organization says that 2 experimental Ebola vaccines being tested on volunteers may not yield sufficient data on efficacy.

A very small segment of the Medicaid-only population-those who are not also eligible for Medicare-accounted for almost half of expenditures for all Medicaid-only enrollees from 2009 to 2011, according to a new report from the Government Accountability Office.

The study, published in the Journal of the National Cancer Institute found that in addition to protecting against 80% of cervical cancers, the new Gardasil-9 has the potential to protect against nearly 19,000 other cancers diagnosed in the United States.

In his blog, a University of Chicago economist says that while non-adherence is a major source of waste in US healthcare-totaling approximately 2.3% of GDP-achieving the optimal level of adherence to treatments is more nuanced than strictly raising adherence rates.

Based on their analysis of a mail-in questionnaire, researchers in Canada found that parents who had their daughters vaccinated differed from those who did not do so in perceived susceptibility to the disease, benefits and barriers of the vaccine, and cues to action.

In this Health Affairs blog, experts provide examples of payment reform in the emergency department that'd move away from the traditional fee-for-service, while at the same time improving outcomes at a lower cost.

Carolinas HealthCare System monitors ICUs in 10 of its hospitals from a command center near Charlotte. The command center is staffed 24/7 with a rotating crew of 7 to 9 nurses and doctors who specialize in critical care.