Clinical

The Swiss drug giant Novartis is looking at alternate pricing models for its heart failure drug Entresto, which is expected to gain FDA approval in August.

A week after JAMA released a report that found more than two-thirds of Americans age 25 years and older are overweight or obese, the American Academy of Pediatrics presented updated guidelines on preventing childhood obesity and recommendations for parents to help their children maintain a healthy weight.

Heterogeneity in Medicaid coverage of the anti-viral agent sofosbuvir is rampant across the United States, with varying reimbursement criteria and lack of conformation to recommendations by professional infectious disease organizations.

Researchers at the University of Michigan Medical School have developed a map of the United States highlighting significant variation in stroke care.

A pediatric long-term care facility in New York initiated an antibiotic-stewardship program to regulate the unnecessary prescribing of antibiotics.

Researchers at the MD Anderson Cancer Center have developed a blood test that can detect very early stages of pancreatic cancer before disease progression.

The JAMA authors recommend that HHS and the US Department of Agriculture pay attention to DGAC's recommendations on fat intake, which do not include an upper limit on total fat consumption.

NICE has updated and redesigned its guideline to support primary care physicians to recognize the signs and symptoms of 37 different cancers and refer people for the right tests faster.

A clinical trial at the University of Alabama will be enrolling patients in the first-ever study of an open-label placebo in cancer.

When evaluating the cost-effectiveness of 4 different interventions to prevent or reduce childhood obesity, researchers found that the benefit of these interventions surpassed the current clinical interventions to treat obesity.

Although drug development is expensive, the high prices being charged for some specialty drugs, like Sovaldi, are not required to induce innovation, Len M. Nichols, PhD, wrote Monday for Morning Consult.

There are 2 strategies for addressing primary medication nonadherence that have seen success, according to Lauren Harner, JD, senior manager for policy at PhRMA.

A study published in the New England Journal of Medicine says a CT scan following a first venous thromboebolism event may not benefit in detecting cancer.

Using mass-spectrometry—based phosphoproteomics, researchers at the Moffit Cancer Center have identified a mechanism by which BRAF/PTEN-null melanoma cells develop resistance to BRAF inhibitors.

In a national study that included 9 million Americans, researchers found that the hospital a patient experiencing post-surgical complications returns to for readmission has an impact on the quality of care the patient receives.

Earlier this week, the FDA heard from various stakeholders and experts from the healthcare industry on how delays in the generic approval process impact healthcare costs.

Researchers at the University of Pennsylvania correlated data from Geographic Information Systems, hospital referral regions, census data, and CDC's State Cancer Profiles, to evaluate whether geographic barriers can prevent access to gynecologic cancer care.

A study published in PLOS ONE found that a higher intake of dietary trans fat correlated with memory loss in men 45 years old and younger.

Despite the increased use of breast-conserving therapy among women with early-stage breast cancer, many women continue to undergo mastectomy, according to a study from researchers at the University of Texas MD Anderson Cancer Center in Houston published in JAMA Surgery.

Scientists at Institut Pasteur in France have repurposed DPP4 inhibitors, used to treat type 2 diabetes mellitus, to boost the body's immune response to tumors.

A report by the American Cancer Society, published in JAMA Internal Medicine, finds smoking significantly increases the risk of cancer-related death.

The findings of inadequate access to providers and outdated information were no surprise to healthcare advocates. Many of the issues are addressed in a giant proposed rule issued by CMS in late May.

Another 2 companies that are using natural language processing and artificial intelligence in their efforts on direct-to-person health coaching.

Published in the Journal of the American Pharmacists Association, the study found a significant improvement in the blood pressure of T2DM patients who were counseled by a pharmacist.

The consensus that drug manufacturers are at fault for high prescription prices comes even though only half the respondents said they were taking medication themselves.