
Opinion|Videos|November 19, 2024
Elinzanetant and the OASIS Trials: Quality of Life and Symptom Relief
Key Takeaways
- Elinzanetant showed significant efficacy in reducing VMS frequency and severity, with rapid symptom improvement compared to other treatments.
- The trials highlighted elinzanetant's positive impact on quality of life for women with severe VMS.
Panelists discuss the methodologies of the OASIS 1, 2, and 3 trials that investigated elinzanetant, highlighting key findings regarding its efficacy in reducing the frequency and severity of vasomotor symptoms (VMS) compared with other treatments, as well as its impact on quality of life and the speed at which patients experienced symptom improvement.
Advertisement
Episodes in this series

Video content above is prompted by the following:
- (PINKERTON) Elinzanetant was studied in the
OASIS 1 and 2 trials , and new data onOASIS 3 were just presented at The Menopause Society’s 2024 Annual Meeting. What was the methodology of these studies? - (SMITH) What are the key findings from the OASIS trials in terms of the reduction in frequency and severity of VMS, and how do these compare with other hormonal and nonhormonal treatments?
- How did elinzanetant impact quality of life for women with severe VMS in the OASIS trials?
- How quickly did patients experience an improvement in symptoms?
- (PINKERTON) What notable adverse events were observed in the OASIS trials with elinzanetant?
- (FIFFICK) How do these safety profiles of elinzanetant and fezolinetant compare with traditional treatments?
Advertisement
Related to this article

A traditional Medicare out-of-pocket (OOP) cap could reduce beneficiaries’ costs but increase annual federal spending by $39 billion to $96 billion.

A systemic sclerosis inception cohort and 17-study meta-analysis found a nearly 5-fold increase in lung cancer risk.

Medicare Advantage plans have varied motivations, strategies, and aspirations for addressing health-related social needs among home health beneficiaries, highlighting a need to expand the scope of supplemental benefits.

2026 Nobel Prize in Medicine honors optogenetics pioneers who turn algae light-sensing protein into neural switches, transforming brain mapping and enabling vision-restoration trials.

Medicare's Transforming Episode Accountability Model is projected to save $46.6 million by 2030, with safety-net hospitals potentially receiving the highest reconciliation payments.

A comparison of 2013 and 2022 data shows that cancer costs are not uniformly rising. Costs decreased for metastatic colorectal cancer but increased for both metastatic non–small cell lung cancer and multiple myeloma.

Employer-mandated enrollment in a high-deductible health plan did not reduce use of oral targeted anticancer medications among patients commercially insured between 2007 and 2021.
Advertisement
Advertisement
Trending on AJMC
1
Pipeline Advances in Sjögren Disease Bring Targeted Therapies Closer
2
VBC Risk Is Outpacing Provider Readiness, CMS Must Act
3
FDA Approves Pirtobrutinib for Untreated CLL/SLL Without 17p Deletion
4
Oral Targeted Anticancer Medication Use Following High-Deductible Health Plan Enrollment
5
