OneOncology Partners With OpenEvidence to Give Physicians Access Within Clinical Workflows

OpenEvidence, an AI-powered medical search platform used by 65% of US physicians, today announced a partnership with OneOncology, a physician-led national platform that supports independent medical specialty practices in 565 care locations.

The OpenEvidence platform collects and organizes peer-reviewed research from major medical journals to support point-of-care decisions. According to a statement from OneOncology, the partnership will embed OpenEvidence into certain clinical applications used across OneOncology’s platform, allowing physicians to use OpenEvidence for clinical evidence retrieval, reference and research.

“The integration is designed to make it easier for physicians at OneOncology partner practices to access OpenEvidence directly within their clinical workflows,” the statement said.

The collaboration is expected to expand, allowing deeper integration with OneOncology’s structured genomic data assets and clinical trials matching systems, “aligning evidence, precision oncology insights, and research opportunities at the point of care,” the statement continued.

OpenEvidence told NBC News in May 2026 that nearly two-third of all physicians, or 650,000 doctors, use the AI platform; independent evaluators confirm it was used for 27 million encounters in April alone, according to data provided by the company.

Community physicians at practices affiliated with OneOncology serve 1.5 million patients in the United States nationwide. These include oncologists, who care for more than half of all patients cancer in locations close to where they live, offering biomarker-driven treatments and, increasingly, clinical trials that were once limited to academic centers.

“Independent physicians across the OneOncology network treat a wide array of cancers across stages, bringing the latest research and treatment options to patients close to home,” Davey Daniel, MD, OneOncology’s chief medical officer, said in the statement. “As physicians who read constantly and stay engaged with emerging science, OpenEvidence will help our partners efficiently access the latest, best-available research and evidence, improving the physician experience and supporting better patient outcomes.”

“Integrating OpenEvidence directly into my workflow will make it easier to access the information I need at the point of care,” said Emily Z. Touloukian, DO, FASCO, president and CEO of Coastal Cancer Center in Myrtle Beach, South Carolina.

“Oncology is where the information problem in medicine is most acute: the literature moves fast, treatment decisions are increasingly personalized, and the stakes are as high as they get,” saidTravis Zack, MD, PhD, chief medical officer, OpenEvidence.

“OneOncology’s partner practice physicians have built a network that brings clinical trials, leading treatment pathways and physician-led innovation into the community. Building OpenEvidence directly into that workflow means the latest evidence, OneOncology’s treatment pathways and relevant trials all converge at the point of care.”

Reference

Hoffman E. OneOncology and OpenEvidence partner to improve cancer care nationwide. News release. August 6, 2026. OneOncology. https://www.oneoncology.com/blog/oneoncology-and-openevidence-partner-to-improve-cancer-care-nationwide