Opinion

Video

Preventive Strategies and Emerging Therapies for Bronchiectasis

Panelists discuss how preventing bronchiectasis exacerbations involves understanding a patient’s past exacerbation pattern, implementing comprehensive airway clearance, patient education, and early intervention.

Clinical Brief: Preventive Strategies for Bronchiectasis

Main Discussion Topics

  • Past exacerbation patterns strongly predict future exacerbations.
  • Patient education about early recognition of exacerbations is crucial.
  • Understanding the consequences of exacerbations motivates prevention.

Key Points for Physicians

  • Review detailed exacerbation history through patient interviews and pharmacy dispensing records.
  • Implement and review bronchiectasis action plans at each visit.
  • Educate patients about the following:
    • Signs and symptoms of exacerbation
    • Increasing airway clearance frequency during early exacerbation
    • Importance of prompt notification and sputum submission
  • Emphasize that exacerbations cause progressive airway damage (“time is lung”)
  • Monitor for sarcopenia and nutritional issues, which can worsen outcomes.

Notable Insights

Beyond airway damage, the systemic effects of exacerbations (sarcopenia, nutritional deficits, increased frailty) can significantly impact long-term prognosis, particularly in older patients.

Clinical Significance

A proactive approach to bronchiectasis management emphasizing exacerbation prevention and early intervention can significantly reduce progressive airway damage and systemic complications.

Newsletter

Stay ahead of policy, cost, and value—subscribe to AJMC for expert insights at the intersection of clinical care and health economics.

Related Videos
EHA 2025 Congress Recap | Image Credit: Venngage
Related Content
AJMC Managed Markets Network Logo
CH LogoCenter for Biosimilars Logo