Gianna Melillo

Compared with traditional cardiovascular disease (CVD) risk factors, such as obesity and high triglycerides, migraine with aura is associated with a higher incidence rate of CVD among female health professionals aged at least 45 years, according to a study published in JAMA.

The FDA today granted accelerated approval to the second biomarker-based indication for Merck’s pembrolizumab (Keytruda), an anti-PD-1 therapy, regardless of tumor type. A companion diagnostic to pembrolizumab, FoundationOne CDx was also today approved by the FDA as only approved companion diagnostic to measure tumor mutational burden.

New results from the Diabetes Prevention Program Outcomes Study (DPPOS), presented at the American Diabetes Association’s 80th Scientific Sessions, showed persistent reductions in type 2 diabetes (T2D) development over an average 22-year follow-up period.

New results from the Diabetes Prevention Program Outcomes Study (DPPOS), presented at the American Diabetes Association’s 80th Scientific Sessions, showed persistent reductions in type 2 diabetes (T2D) development over an average 22-year follow-up period.

A study conducted in Boston-area hospitals found low prevalence of asymptomatic coronavirus disease 2019 (COVID-19) infections among pregnant women, while a systematic review concluded maternal transmission of the virus to neonates is uncommon.

Research presented at the American Diabetes Association's 80th Scientific Sessions offers new insights into the future of glycemic control, diabetes self-management, and remote care.

American women die in childbirth at a higher rate than in any other developed country, while non-Hispanic Black women are more than 3 times more likely to have a maternal death than white women in the United States, according to a review presented at the American Diabetes Association’s 80th Scientific Sessions.

Obesity contributes to development of youth-onset type 2 diabetes (T2D) and can lead to detrimental health outcomes in adulthood. Researchers explored this relationship and offered insights on addressing the problem during a session at the American Diabetes Association’s (ADA) 80th Scientific sessions, held virtually due to coronavirus disease 2019 (COVID-19).

Hypertensive disorders account for approximately 25% of excess cases of maternal stroke associated with migraine, according to research published in JAMA Neurology.

Patients hospitalized for coronavirus disease 2019 (COVID-19) who have diabetes account for more than 20% of individuals admitted to intensive care units, according to new guidance published in the Journal of Clinical Endocrinology & Metabolism.

Evidence from 2 randomized clinical trials suggests that long-term intraocular pressure variability does not add substantial explanatory power to a prediction model determining which individuals with untreated ocular hypertension will develop primary open-angle glaucoma, according to a study published in JAMA Ophthalmology.

The Association of Diabetes Care & Education Specialists (ADCES) released a consensus report outlining strategies health care stakeholders can follow to increase access to and utilization of diabetes self-management education and support (DSMES).

Patients with cluster headache are at an increased risk of anxiety and depression, especially in the presence of coexisting migraine, according to a study published in The Journal of Headache and Pain.

Researchers discovered retinal data can predict which individuals have cerebrospinal fluid biomarkers of Alzheimer disease pathology before cognitive decline is detectable, according to a study published in PLOS One.

Researchers created a test to determine which children with Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, And Dihydroorotase (CAD) gene deficiency will benefit from receiving a nutritional supplement previously deemed effective in children with the condition, according to a study published in Genetics in Medicine.

Microperimetric mean sensitivity and deep scotoma points may be useful end points for clinical trials investigating emerging treatments for Stargardt disease, according to a study published in JAMA Ophthalmology.

The subdiagnosis of migraine, but not the presence of vestibular symptoms, can predict balance impairments in migraineurs, according to a study published in The Journal of Headache and Pain.

Bristol Myers Squibb announced the commercial launch of Zeposia (ozanimod) for relapsing multiple sclerosis (RMS). The oral treatment is the first and only approved sphingosine-1-phosphate receptor modulator with no genetic test or first dose observation at initiation.

For individuals with both diabetes and colorectal cancer, high adherence to oral diabetes medication was associated with a significantly reduced risk of overall mortality compared with lower adherence, according to a study published in Cancer Epidemiology, Biomarkers & Prevention.

Research has established an association between social risk factors and child health outcomes, while professional medical organizations have endorsed screening for such factors in clinical settings. Providing an in-person patient navigator to address family social needs leads to a decrease in child health care utilization, according to a study published in JAMA Network Open.

Strabismus is associated with reduced functional vision and eye-related quality of life (ER-QOL) in children, according to a study published in JAMA Ophthalmology. Because of this, when defining management goals, the association of strabismus with functional and ER-QOL in children should be considered.

Insulin out-of-pocket costs remained relatively flat between 2006 and 2017 among privately insured patients, despite increased insulin prices paid by insurers, according to research published in JAMA Internal Medicine.

Between 1997 and 2012, the inpatient burden of migraine cost rapidly increased in the United States, according to a study published in PRS Global Open.

Medicaid expansion was associated with a decrease in nonprofit hospitals’ burden of providing uncompensated care, according to a study published in JAMA Network Open. However, hospitals did not redirect this financial relief toward spending on additional community benefits.

Researchers in India were able to successfully use retinal diagnostics via smartphone adaptors to detect a diabetes-related eye disease, according to a study published in Ophthalmology.

Surgical decompression of supraorbital and supratrochlear nerves may aid migraineurs experiencing moderate to severe chronic frontal migraine who do not respond to medications, according to a study published in Plastic and Reconstructive Surgery (PRS) Global Open.

Migraineurs’ brains experience disrupted functional connectivity (FC) between subregions in the sensorimotor areas and cortex, according to a study published in The Journal of Headache and Pain.

In the first report of its kind, researchers examined the combined effect of liraglutide and propranolol on the hearts of patients with both type 2 diabetes and cirrhosis.

Refractive evaluation should be considered for working-age adults with eye disease and reduced visual acuity, especially if they are new to seeking care for low vision, according to a study published in JAMA Ophthalmology.

A deep learning model appears to be useful in classifying images to provide corneal information and preliminarily identify corneas at risk for refractive surgery, according to a study published in JAMA Ophthalmology.