
In a small study, evidence suggested 8-Hydroxy-2'-deoxyguanosine levels negatively correlated with a test of exercise endurance.
Jared is a freelance writer for The American Journal of Managed Care® (AJMC®), and previously worked as a senior editor for HCPLive® at MJH Life Sciences®.
He has an MA from University of Sioux Falls. You can connect with Jared on LinkedIn.

In a small study, evidence suggested 8-Hydroxy-2'-deoxyguanosine levels negatively correlated with a test of exercise endurance.

Patients whose endurance increases will likely have a higher quality of life and ability to carry out daily functions, the authors said.

The report suggests remission and disease activity state alone are not the most important risk factors in pregnant women with well-controlled systemic lupus erythematosus.

Evidence suggests higher levels of iron in pulmonary macrophages heightens the risk of infectious exacerbations.

The research suggests a computed tomography-readable biomarker could help clinicians better understand individual cases of chronic obstructive pulmonary disease.

A new retrospective analysis proposes cutoff values that could help physicians identify patients at highest risk of severe kidney complications.

The study found 1 in 5 physicians felt acne had a negative impact on their working lives.

New evidence suggests macrophage regulation could be an important area of inquiry in systemic lupus erythematosus, but the research is in its early stages.

The 30-day readmission rate among patients receiving post-hospitalization at-home interventions was roughly half the rate of a control group.

Graft-versus-host disease (GVHD) is common, yet it is poorly understood and its symptoms can be difficult to recognize.

As noninvasive ventilation grows in popularity, new research examines when the therapy works, and when clinicians should be cautious.

The new study suggests certain sub-categories of patients are at particularly high risk.

The study points to the challenges of treating chronic obstructive pulmonary disease in a remote region in a country with a high smoking rate.

The patient had no obvious pulmonary symptoms, but a routine chest X-ray helped investigators arrive at the diagnosis.

The new research is aimed at a patient group often left out of research studies.

The new recommendations for systemic lupus erythematosus (SLE) use disease activity index scores and evaluator’s global assessment measures, but they do not include serology.

A new study comparing intensive care unit stays among patients with Parkinson disease and controls without the disease found the former have more severe illness, but both groups have similar survival rates.

A new study characterizes the rate of allergic contact dermatitis among patients given skin adhesives.

A new report finds patients with systemic lupus erythematosus and 5 other autoimmune disorders face an increased risk of gastric cancers.

A total of 92 gene variants were sequenced, 41 of which were novel.

The patient experienced lasting improvement when belimumab was added to her regimen after 2 years.

Women with systemic lupus erythematosus (SLE) were twice as likely to experience carotid plaque buildup during the 5 years of this study.

In a new review article, investigators outline the challenges to studying the disease, but also point to big data as an important tool moving forward.

Investigators found anti-ribosomal P protein antibodies, a serological marker for systemic lupus erythematosus (SLE), were linked with higher ferritin levels, independent of interleukin 6 levels.

Despite the increase in relapse risk, 2-year survival for patients with graft-versus-host disease (GVHD) who received matched sibling donor (MSD) allogeneic hematopoietic cell transplant (allo-HCT) administered post-transplant cyclophosphamide remained similar compared with patients receiving cyclosporine A with methotrexate prophylactically.

Patients who took supplements had improvements, although they did not become apparent until patients had been taking supplements for a year.

Children with uncontrolled asthma had a 3- to 6-times the risk of hospitalization for COVID-19, the investigators found.

Fifty-one therapies have been approved for rare neurological diseases since the FDA passed the Orphan Drug Act in 1983.

Patients with SLE had higher levels of Wnt5A if they were experiencing active disease.

A new case report highlights a patient who presented with seizure-like symptoms but was later diagnosed with the rare lysosomal storage disorder.

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