Jared Kaltwasser

Patients with BRAF-V600 mutated metastatic melanoma have new treatment options to consider, but scientists are still waiting on additional data to help choose which first-line treatments are best for which patients.

Patients over the age of 65 had similar rates of serious adverse events, and nearly identical progression-free survival, when compared with younger patients.

A review of cases using MRI with and without contrast agent found perfect or near-perfect agreement in most cases when evaluating patients with short stature for growth hormone deficiency.

The new study, based on an analysis of existing literature and a replication cohort, helps clarify the role of a variant in microRNA-146a.

By year 5 of therapy with disease-modifying anti-rheumatic drugs (DMARDs), only about one-third of patients with psoriatic arthritis (PsA) were expected to be continuing with their therapy.

People who suffered trauma as a child appear to be at a higher risk of fibromyalgia, although it is unclear exactly why.

Patients with systemic lupus erythematosus (SLE) said they still suffered significant pain and fatigue, even though they reported high rates of satisfaction with their therapies.

This new analysis aimed to pinpoint more rigorous predictors of mortality, and it was able to identify “excellent” but not “outstanding” ones, according to the investigators.

Autophagy inhibition could help patients who develop resistance to BRAF inhibitors, but a new review shows important questions remain.

Randomized controlled trials on asthma hospitalization prevention are limited, but patient and caregiver education should be a top priority, investigators said.

A new report suggests corticosteroids likely are not a panacea for ocular surface disease, a potential adverse effect of trabeculectomy.

Patients with axial spondyloarthritis waited the longest, according to new research.

Among patients who suffer an in-hospital cardiac arrest, acute kidney injury (AKI) raised the risk of all-cause in-hospital mortality from about 30% to more than 60%.

A new mathematical model highlights the challenges of preventing Clostridioides difficile transmission in the hospital.

A study suggests that for patients with chronic kidney disease (CKD), the more components of metabolic syndrome present, the higher that patient’s risk of adverse cardiovascular outcomes.

Results from the FUTURE 5 study show that more than 80% of patients had no radiographic progression of psoriatic arthritis, regardless of dose cohort or whether a loading dose was used.

A new report could eventually help investigators better understand which patients with diffuse large B-cell lymphoma (DLBCL) are most likely to respond to certain therapies.

A recent study found half of hospitalized children received a flu vaccination when their providers used a clinical decision support tool; however, that is still lower than the 63% national average for all children.

Most patients said they had received instruction on how to use their inhalers from a pharmacist or physician, but only 21% said they had received instruction from both.

A recent study aimed to understand whether psoriasis and psoriatic arthritis are independent risk factors for coronary calcification and coronary artery disease. It found both correlate with higher rates of calcification, but only psoriasis was linked with severe calcification and disease.

New strategies are currently being investigated to find out how to avoid resistance to immune checkpoint inhibitors and BRAF/MEK inhibitors.

More than three-quarters of patients with rheumatic diseases quarantined and kept social distance during the pandemic, according to a new global survey.

Patients with nephrotic syndrome were far more likely than healthy controls to suffer end-stage kidney disease, particularly if they had focal segmental glomerulosclerosis or membranous nephropathy.

Nearly 9 in 10 children given intravenous (IV) magnesium for refractory asthma ended up being admitted to the hospital, but new research suggests that may be partly due to a lack of clarity about the therapy’s safety profile.

An uptick in modeling and genomic data caused by the COVID-19 pandemic could lead to important infection-prevention measures in health care settings.

A new prospective cohort study suggests joint pain, rather than skin pain or disease severity, correlates with greater use of analgesics.

The new report compared the benefits of sodium-glucose co-transporter 2 (SGLT2) inhibitors with those of other glucose-lowering drugs and found lower rates of heart disease and mortality.

Although body weight affected pharmacokinetics, the investigators said dosing adjustments based on weight were not warranted.

A new report finds roughly three-quarters of patients with ankylosing spondylitis, psoriatic arthritis, and rheumatoid arthritis used painkillers, although biologics appear to curb the need for nonsteroidal anti-inflammatory drugs, in particular.