Steven D. Nathan, MD
Articles
Unmet Needs in IPF- and ILD-Related Pulmonary Hypertension and Emerging Therapy for IPF
Steven Nathan, MD, discusses additional noteworthy data from CHEST 2024 on emerging therapies for IPF and PAH and highlights his excitement for ongoing research focused on improving early detection, personalized treatments, and improving long-term patient outcomes.
Key Insights on the Use of Inhaled Treprostinil in Treating CTD-PAH
Steven Nathan, MD, discusses how the study on inhaled treprostinil for CTD-PAH demonstrates its comparable efficacy to intravenous and subcutaneous forms, with a better safety profile, which could lead to improved patient adherence and management of CTD-PAH.
Insights on Managing Cough Symptoms in Patients With IPF
Steven Nathan, MD, discusses how the findings from the study on oral nalbuphine extended release suggest that this treatment may offer an effective option for managing IPF-related cough, providing significant relief in terms of both frequency and severity, which could shift current management strategies by introducing a more targeted, pharmacologic approach to addressing one of the most challenging symptoms of IPF.
Evaluating Cough Relief With Oral Nalbuphine in Patients With IPF
Steven Nathan, MD, discusses the abstract “Analysis of Relief-of-Cough in Patients With Idiopathic Pulmonary Fibrosis Treated With Oral Nalbuphine Extended Release,” which aimed to assess the effectiveness of oral nalbuphine extended release in providing relief from chronic cough in patients with IPF; the study used a clinical trial design to evaluate cough severity, with results showing that nalbuphine significantly reduced cough frequency and intensity, offering a potential new treatment option for managing this common and debilitating symptom of IPF.
Implications of IPF Survival Data for Clinical Practice and Early Intervention
Steven Nathan, MD, discusses how the data from the IPF-PRO Registry highlights the critical relationship between early diagnosis and prognosis in IPF, revealing that FVC percent predicted, oxygen use, BMI, and age are key indicators of long-term survival, underscoring the importance of early identification, and personalized treatment plans to improve patient outcomes.
Key Predictors of Survival in IPF: Findings From the IPF-PRO Registry
Steven Nathan, MD, discusses the abstract “Predicting Long-Term Survival in Patients With Idiopathic Pulmonary Fibrosis: Data From the IPF-PRO Registry,” which aimed to identify key predictors of long-term survival in IPF using data from the IPF-PRO Registry; the study employed a classification and regression tree model to analyze variables such as FVC percent predicted, oxygen use, BMI, and age, and found that factors such as oxygen use and FVC levels were strong predictors of survival beyond 5 years.
CHEST 2024: Updates in IPF and PAH Care
Coming into CHEST 2024, Steven Nathan, MD, discusses how the largest unmet needs in the treatment and management of IPF and PAH include improving early diagnosis, addressing symptom management (particularly chronic cough), and developing more effective, accessible therapies to enhance long-term patient outcomes.
