Authors
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A Value Proposition for Pragmatic Clinical TrialsThe authors examine the origin, benefits, and challenges of pragmatic clinical trials to assess the ultimate value of this research design.
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Biosimilars at ASH 2019: Data on Truxima and Competitors for EculizumabResults for Truxima, recently launched in the United States, and complement inhibitors were presented at the 61st American Society of Hematology Annual Meeting and Exposition.
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The FLU-FIT Program: An Effective Colorectal Cancer Screening Program for High Volume Flu Shot ClinicsOffering home fecal immunochemical tests to eligible patients during influenza vaccination clinic increases colorectal cancer screening rates.
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Cost-effectiveness Evaluation of a Home Blood Pressure Monitoring ProgramA technology-based, pharmacist-run home blood pressure monitoring program improves health outcomes by investing $20.50 per mm Hg systolic blood pressure lowered and $3300 per life-year gained.
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FDA Oncology Center of Excellence Moves Forward on Coordinated Clinical Reviews, Integrated Approach to the Clinical Evaluation of Oncology ProductsAn overview of the FDA's Oncology Center of Excellence-a collaborative approach to the clinical approval process.
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A Mid-South Chronic Disease Registry and Practice-Based Research Network to Address DisparitiesThe authors report the experience of one of the first Southern US communities to develop a comprehensive health care data repository for tracking processes and outcomes of care and identifying areas of greatest need.
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Screening Cardiac Surgery Patients for MRSA: An Economic Computer ModelRoutine preoperative MRSA screening of cardiac surgery patients could provide substantial economic value to third-party payers and hospitals under a wide range of circumstances.
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Variation in the Cost of Medications for the Treatment of Colorectal CancerUsing data from a nationwide registry, this study revealed significant variation in the use and cost of contemporary regimens for colorectal cancer.
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Improving Medication Understanding Among Latinos Through Illustrated Medication ListsA randomized controlled trial found that plain-language, illustrated medication lists improved medication understanding among Latinos.
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Health Insurance Literacy: Disparities by Race, Ethnicity, and Language PreferenceRacial/ethnic minorities are disproportionately at risk for adverse health and financial consequences due to lower health insurance literacy compared with white enrollees.
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Benefits and Risks of Live Attenuated Influenza Vaccine in Young ChildrenUse of live attenuated influenza vaccine in young children has a favorable benefit-risk profile.
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Geographic Variation in Surgical Outcomes and Cost Between the United States and JapanCompared with Japan, the United States has substantially less geographic variation in surgical outcomes, but it has higher variation in cost.
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Impact of Emergency Physician–Provided Patient Education About Alternative Care VenuesPostvisit phone education from an emergency physician and/or mailed information about alternative venues of care reduced subsequent emergency department (ED) utilization for low-acuity treat-and-release adult ED patients.
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Physician Practice Variation Under Orthopedic Bundled PaymentThis study demonstrates that variation reduction is an important, but not requisite, component of organizational success under orthopedic bundled payment.
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Compliance, Persistence, and Switching Patterns for ACE Inhibitors and ARBsThis drug-utilization study in a prescription database of more than 50,000 patients analyzed compliance, persistence, and switching behavior for ACE inhibitors and ARBs.
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Referrals and the PCMH: How Well Do We Know Our Neighborhood?A descriptive analysis of specialty referral patterns in an academic, internal medicine patient-centered medical home (PCMH).
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An Intervention for VA Patients With Congestive Heart FailureAn intervention of variable intensity for congestive heart failure showed some improvements but no survival effect, suggesting a tradeoff between intervention cost and intensity and survival benefit.
