Asthma

In children with allergic rhinitis, those with allergic asthma with postnasal drip (PND) coughed more overnight than children with atopic asthma without PND, according to a recent study.

At-risk rates of asthma morbidity in children varied across census tracts in Washington, DC, and were significantly correlated with social determinants of health in each area, according to a recent study.

Providers from an asthma primary care program found telemedicine to be effective in both caring for children with asthma and addressing unmet social needs that may exacerbate their asthma outcomes.

Worse asthma control and higher body mass index (BMI) are associated with lower exercise capacity in patients with severe asthma, especially female patients, according to a recent study.

Patients with asthma hospitalized with COVID-19 in Michigan in 2020 had more severe outcomes after taking certain factors into account, according to a recent study.

Most of the children readmitted to hospitals for asthma in Australia were preschool aged.

Although approved for use among patients with severe or refractory asthma, few studies have investigated its effectiveness among patients with comorbid mild to moderate asthma and chronic rhinosinusitis with nasal polyps (CRSwNP).

Research presented at the European Academy of Allergy and Clinical Immunology Annual Congress show the safety and efficacy of dupilumab across several progressive diseases with underlying type 2 inflammation, including eosinophilic esophagitis (EoE), severe asthma, and severe chronic rhinosinusitis with nasal polyps.

Neighborhood characteristics, race, and ethnicity were found to be risk factors for developing asthma in childhood, suggesting inequities in children’s respiratory health.

Most patients taking a biologic stayed on the therapy, and most saw decreases in exacerbations, a new study has found.

Among patients with severe asthma with low eosinophils untreated with biologics, there is a high burden of disease among those who have suboptimal disease control.

About 70% of caregivers studied reported that they preferred to use the emergency department for treatment for asthma exacerbations, indicating current education is insufficient for managing asthma at home.

Children with severe and poorly controlled asthma generally face a greater risk of sleep-disordered breathing.

High-intensity interval training (HIIT) also improved quality of life and physical activity levels while reducing anxiety and depression levels.

Dupilumab-induced increases in mean eosinophil counts were shown to wane over time in patients with asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and atopic dermatitis (AD), with incidence of eosinophilia not shown to reduce efficacy of the biologic.

Little data exist on the effectiveness of dupilumab in Black and Hispanic children, even though severe asthma disproportionately affects these populations.

Dupilumab was associated with reductions in exacerbations and oral corticosteroids (OCS) dosage, as well as improved lung function, in patients with OCS-dependent asthma with and without comorbid chronic rhinosinusitis with nasal polyps.

A survey of patients and health care providers found both groups favor at-home administration of biologics when possible.

Dupilumab improved lung function and reduced severe asthma exacerbation rates in children with moderate to severe asthma with or without atopic comorbidities.

Pediatric patients with asthma and their caregivers are faced with significant health and cost burdens, and biologics provide an opportunity to improve quality of life and asthma control, according to a panel of experts.

Patients with comorbid chronic rhinosinusitis (CRS) with nasal polyps and severe asthma reported significant improvement in their sense of smell when treated with the biologics omalizumab, mepolizumab, reslizumab, or benralizumab, with no significant differences observed between the treatment groups.

In this new study, researchers wrote of the implications that detailed an association between asthma and exposure to particulate matter less than or equal to 2.5 mcm.

Patients with aspirin-exacerbated respiratory disease (AERD) who initiated treatment with dupilumab as an add-on asthma or chronic rhinosinusitis with nasal polyps therapy reported rapid clinical improvement that was sustained after 3 months.

Using an inhaled glucocorticoid in addition to usual care reduced the rate of severe asthma exacerbations and improved other markers of disease severity.

The study is the first to find an association between adults with asthma and the risk of obesity developing later.