February 23rd 2023
February 23rd 2023
In Vitro Diagnostic Test Accurately Predicts Response to Treatment in Breast Cancer
December 8th 2018BioNTech AG, a drug developer that specializes in cancer immunotherapies, announced last month new results from a clinical performance evaluation study of a molecular in vitro diagnostic test for quantitative detection of mRNA expression of certain genes.
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Study Shows Women Could Benefit From Mammography Screening at Age 30
November 30th 2018In a study presented at the annual meeting of the Radiological Society of North America (RSNA), researchers found that starting mammography screening at age 30 may benefit women with at least 1 of 3 risk factors: dense breasts, a personal history of breast cancer, or a family history of breast cancer.
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Breast Cancers Recruit Cells From Bone Marrow to Increase Their Growth, Study Says
November 26th 2018Fibroblasts play a role in the spread of cancer, and a recent study showed that breast tumors can boost their growth by recruiting bone marrow–derived mesenchymal stromal cells to primary breast tumors
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Review Looks at Role Lipocalin 2 Might Play in Spread of Breast Cancer
November 17th 2018A recent review looked at the role lipocalin 2 (LCN2), a secreted glycoprotein that transports small lipophilic ligands, might play in metastatic triple-negative breast cancer (TNBC) and the possibility of potential LCN2-targeting agents.
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Radiologists Should Inform Patients When BAC Is Detected at Mammography
November 10th 2018Researchers recently reported findings from a study designed to determine patient attitudes about mammographic reporting of breast arterial calcification (BAC), result of the BAC communication, and subsequent action.
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Using AI to Process Mammography Results in Place at Massachusetts General
November 7th 2018Massachusetts General Hospital (MGH) is using artificial intelligence (AI) to process screening mammographies after a retrospective study found that AI can measure breast density—a risk factor for having tumors that could be missed during a scan—at the screening level of an experienced radiographer.
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Rare Breast Cancer Genetic Risk Linked to Greater Chance of Missed Tumors
November 2nd 2018A new study offers insights into ways to improve breast cancer screening with a new understanding of how genetic risk variants affect disease progression and mode of detection. The study found that the presence of certain rare mutations was indicative of increased risk from interval breast cancers and death.
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Study Tries to Pinpoint Factors Predicting Pain After Breast Cancer Surgery
October 30th 2018As with other kinds of surgery, patients undergoing operations for breast cancer can experience persistent postsurgical pain, which can negatively affect quality of life. Researchers in Tokyo conducted a study to see if they could determine the predictive value and accuracy of an acute pain trajectory, measured by pain intensity at 1 day after the surgery and pain prevalence at 6 months later.
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Palbociclib Plus Fulvestrant Increases OS in HR+, HER2-Negative Breast Cancer
October 26th 2018A recent trial sought to assess the effect of palbociclib on overall survival (OS) and the efficacy of subsequent therapy in patients with hormone receptor–positive (HR+), HER2-negative advanced breast cancer.
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Shorter Treatment Option Studied for HER2 Early Breast Cancer
October 20th 2018Women with HER2-positive early breast cancer with small tumors have similar disease-free survival and lower risk of cardiac toxicity with a 9-week course of adjuvant trastuzumab compared with those treated for 1 year, according to a study presented at the ESMO 2018 Annual Congress. A second study showed that a 6-month course of adjuvant trastuzumab was cost-effective compared to 12 months.
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Study Examines Impact of Deviating From NCCN Guidelines for Metastatic Breast Cancer
October 13th 2018A recent study looked at regimens concordant with the National Comprehensive Cancer Network (NCCN) Guidelines for Metastatic Breast Cancer (MBC) in order to describe categories of nonconcordant treatments; evaluate patient- and provider-level factors associated with nonconcordance; and determine the impact of nonconcordance on mortality, Medicare spending, and rates of healthcare utilization.
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Adherence to NCCN Breast Cancer Guidelines Improves Outcomes
October 6th 2018In a study presented at the American Society of Clinical Oncology Quality Care Symposium last month, researchers looked to assess the adherence to National Comprehensive Cancer Network (NCCN) guidelines in the neoadjuvant treatment of breast cancer and the impact on outcomes.
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Second Opinions Beneficial for Patients With Breast Cancer
October 6th 2018A recent retrospective analysis examined changes in diagnosis after a second opinion for patients with breast cancer from a multi-disciplinary tumor board review at a National Cancer Institute-designated cancer center.
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Patient Navigation Programs Need to Address Gender, Race in Breast Cancer, Study Says
September 29th 2018Black women are more likely to be diagnosed at a later stage of breast cancer in part due to barriers to timely screening mammography, a study reported, leading to a disparity in mortality and survival outcomes.
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Lack of Discussion Around Cancer Treatment Costs Leads to Financial Toxicity
September 29th 2018Earlier this week, 3 studies were released that investigated the financial difficulties seen in patients living with cancer. Such difficulties are referred to as “financial toxicity,” which was studied in patients with metastatic breast cancer and older patients, as well as the conversations about cost of care that women with breast cancer have with their physicians.
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Clinical Outcomes and Healthcare Use Associated With Optimal ESRD Starts
Optimal end-stage renal disease (ESRD) starts were associated with lower 12-month morbidity, mortality, and inpatient and outpatient utilization in an integrated healthcare delivery system.
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More Data Necessary to Determine Best Treatment Option in Basal Cell Carcinoma
September 21st 2018Although many different treatments exist for basal cell carcinoma (BCC), many methods have not been compared in head-to-head randomized trials. A review recently published in Annals of Internal Medicine looked to evaluate the comparative effectiveness and safety of treatments in adults with BCC.
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Are Integrated Practice Units Working in Breast Cancer Clinical Pathways?
September 19th 2018Researchers examining how well integrated practice units (IPU) are implemented across 7 cancer centers in Europe found there was no clear, consistent strategy for developing and implementing IPUs, in an analysis that focused mostly on breast cancer clinical pathways.
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