Colorectal Cancer

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ctDNA analysis | Image credit: Thaweechai - stock.adobe.com
ctDNA Response Predicts Outcomes in MSI-H mCRC Immunotherapy

June 18th 2025

Early circulating tumor DNA (ctDNA) changes predict survival in mismatch repair or microsatellite instability–high (dMMR/MSI-H) metastatic colorectal cancer (mCRC) treated with immune checkpoint inhibitors (ICIs).

FIT test CRC - Paul Maguire - stock.adobe.com
Starting Colorectal Cancer Screening at Age 40 Cuts Death Risk by 39%, Study Finds

June 12th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com
Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

June 6th 2025

CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
Blood Test Detects 79% of Colorectal Cancers in Screening Study

June 3rd 2025

The authors emphasized the need for further research into improving the diagnostic performance of both blood- and stool-based tests, particularly to enhance early lesion detection. | Image credit: SewcreamStudio - stock.adobe.com
FIT Outperforms Blood-Based cfDNA Test in Detecting Precancerous Colorectal Lesions

May 31st 2025

More News

Colorectal Cancer | Image credit: Dr_Microbe - stock.adobe.com
April 26th 2024

Lower Incidence of Anastomotic Leakage Linked to PGA Sheets

Julia Bonavitacola
Polyglycolic acid (PGA) sheets could help reduce rates of anastomotic leakage, which is a leading cause of mortality in colorectal cancer surgeries.
Doctor holding large intestine | Image credit: Orawan - stock.adobe.com
April 23rd 2024

Nomogram Model Could Predict Survival in Stage III CRC

Julia Bonavitacola
New data show that survival in patients living with postoperative colorectal cancer (CRC) could be predicted using a nomogram model.
Colorectal Diagram | Image credit: mi_viri - stock.adobe.com
April 18th 2024

Low-Volume Hospitals Had Higher Reoperation Rate, Postoperative Complications in CRC

Julia Bonavitacola
Patients opting for elective colorectal surgery to address colorectal cancer (CRC) could have different rates of reoperation and postoperative complications based on the size of the hospital.
Telephone | Image credit: chinnarach - stock.adobe.com
April 16th 2024

Screening Program Contributed to Increased Screening Completion for CRC

Julia Bonavitacola
Screening completion increased when using sequential automated and personalized strategies for colorectal cancer (CRC) in different demographic groups.
Processed foods | Image credit: Daisy Daisy - stock.adobe.com
April 9th 2024

Ultraprocessed Foods, Ice Cream Associated With Mortality in CRC Survivors

Julia Bonavitacola
Among patients who have survived colorectal cancer (CRC), there was an association between increased mortality due to CRC or cardiovascular disease and higher intake of ice cream and ultraprocessed foods.
Colorectal cancer | Image credit: peterschreiber.media - stock.adobe.com
April 5th 2024

Prognostic Significance May Exist for CRC Tumor Sites

Julia Bonavitacola
A new study found that tumor sites in stage I-III colorectal cancer (CRC) could affect recurrence-free survival and survival after recurrence in patients.
Diagram of Intestines | Image credit: LIGHTFIELD STUDIOS - stock.adobe.com
April 2nd 2024

Surgeries for CRC Affected by COVID-19 Pandemic

Julia Bonavitacola
A decrease in surgeries to address colorectal cancer (CRC) could lead to unknown consequences, including intensifying challenges faced by the patients.
Colorectal cancer | Image credit: Sebastian Kaulitzki - stock.adobe.com
March 25th 2024

Cetuximab Effective in Patients With CRC After Induction Chemotherapy

Julia Bonavitacola
A study found that cetuximab along or with chemotherapy was an effective option in patients with metastatic colorectal cancer (CRC).
Couple with Doctor | Image credit: Chinnapong - stock.adobe.com
March 20th 2024

Posttraumatic Growth Intervention Improved Psychological, Physical Health in Patients With CRC and Spouses

Julia Bonavitacola
Patients with colorectal cancer (CRC) and spousal caregivers were found to benefit from a couple-based posttraumatic growth intervention visits in a randomized controlled study.
Blood test | Image credit: filin174 - stock.adobe.com
March 15th 2024

Cell-Free DNA Test Has High Sensitivity for Colorectal Cancer

Julia Bonavitacola
A blood-based test using cell-free DNA had high sensitivity for colorectal cancer, high specificity for advanced neoplasia, and some sensitivity for advanced precancerous lesions.
Colorectal Cancer | Image credit: mi_viri - stock.adobe.com
March 14th 2024

Disease-Free, Overall Survival Lower in Patients With CRC Treated With PE, CRS/HIPEC

Julia Bonavitacola
Patients with stage IV colorectal cancer (CRC) had lower overall and disease-free survival if they had a pelvic exenteration (PE) or cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC).
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
March 7th 2024

Early Screening Model Displays High Accuracy in Predicting CRC

Julia Bonavitacola
A prediction model using age, body mass index, lifestyle, waist circumference, and family history had high accuracy when used to predict colorectal cancer (CRC) in China.
Large intestine in doctor's hands | Image credit: Orawan - stock.adobe.com
March 4th 2024

Heald Anal Stent Effective in Reducing Anastomotic, Rectal Stump Leaks After CRC Surgery

Julia Bonavitacola
Patients who had surgery for colorectal cancer (CRC) were able to avoid anastomotic or rectal stump leaks by using a Heald anal stent.
Frail woman using walker | Image credit: Paul Maguire - stock.adobe.com
February 26th 2024

Overall, Disease-Free Survival Worse in Frail Patients With CRC

Julia Bonavitacola
Patients with colorectal cancer (CRC) who were also frail were found to have worse survival when compared with patients who weren’t frail.
Colorectal cancer | Image credit: SciePro - stock.adobe.com
February 21st 2024

Intensive Surveillance Cost-Effective in Stage II, III CRC

Julia Bonavitacola
Intensive surveillance after resection on patients with colorectal cancer (CRC) was less cost-effective in stage I but most cost-effective in stage II and III disease.
Doctor talking to patient | Image credit: bongkarn - stock.adobe.com
February 14th 2024

Bundling Interventions to Promote CRC, SDOH Screenings Found Feasible, Effective

Julia Bonavitacola
Combining interventions to encourage screenings for colorectal cancer (CRC) and social determinants of health (SDOH) was found to improve screening rates in CRC without decreasing rates of screenings for SDOH.
Black woman in hospital | Image credit: N F/peopleimages.com - stock.adobe.com
February 8th 2024

Non-White Patients With CRC Have Increased Odds of Emergent Resection

Julia Bonavitacola
Emergent colorectal cancer (CRC) resection was found to be more prevalent in patients who identified as non-White.
Colorectal Cancer | Image credit: mi_viri - stock.adobe.com
February 5th 2024

Rectal Surgery, Male Sex Risk Factors for Anastomotic Leakage

Julia Bonavitacola
Several risk factors put patients with colorectal cancer at increased risk of anastomotic leakage after elective surgery.
Colorectal Cancer | Image credit: Dr_Microbe - stock.adobe.com
February 1st 2024

Telehealth, e-Health Psychological Interventions Potentially Promote Sexual Health in CRC

Julia Bonavitacola
Patients with colorectal cancer (CRC) could participate in telehealth and e-health interventions to promote their sexual health, although efficacy of these interventions needs to be further studied.
Adult measuring waist | Image credit: BillionPhotos.com - stock.adobe.com
January 18th 2024

Causal Relationship Found Between Obesity in Metabolic Syndrome and CRC

Julia Bonavitacola
Obesity related to metabolic syndrome was found to have a causal relationship with colorectal cancer (CRC), although this causal relationship did not exist in the opposite direction.
Woman in headscarf | Image credit: Africa Studio - stock.adobe.com
January 17th 2024

American Cancer Society Report Estimates Higher Cancer Incidence in 2024

Julia Bonavitacola
Incidence of colorectal cancer is expected to rise in both male and female patients aged 50 years and younger.
Doctor displaying human intestine | Image credit: mi_viri - stock.adobe.com
January 16th 2024

POSSUM, Other Scoring Systems Unable to Estimate Perioperative Complications in CRC

Julia Bonavitacola
Mortality and morbidity in patients with colorectal cancer (CRC) cannot be accurately predicted using the Physiological and Operative Severity Score for the enumeration of Mortality and Morbidity (POSSUM) in the present day.
Colorectal Cancer | Image Credit: SciePro - stock.adobe.com
January 9th 2024

Risk of Colorectal Cancer Higher in Patients With Chronic Kidney Disease

Julia Bonavitacola
Patients with chronic kidney disease are at a higher risk of developing any stage of colorectal cancer.
Probiotic bottle | Image credit: Aleksandra Gigowska - stock.adobe.com
January 5th 2024

Probiotics Prevent Surgical Site Infections in Patients With CRC

Julia Bonavitacola
Patients with colorectal cancer (CRC) undergoing operations were able to prevent postoperative infections and shorten hospital stays by taking probiotics beforehand.
Intestines | Image credit: mi_viri - stock.adobe.com
January 3rd 2024

Least Differentiation Analysis Reliably Measures LNM Risk in Submucosal Invasive CRC

Julia Bonavitacola
Tumor grading via least differentiation analysis was found to be a way to measure the risk of lymph node metastasis (LNM) in patients with submucosal invasive colorectal cancer (CRC).
Top 5 Most-Read Colorectal Cancer Articles of 2023
December 30th 2023

Top 5 Most-Read Colorectal Cancer Articles of 2023

Julia Bonavitacola
The topics included clinical staging of colorectal cancer, FDA approvals, and a study published in the print version of the American Journal of Managed Care®.
Doctor holding illustration of intestine | Image credit: mi_viri - stock.adobe.com
December 21st 2023

Preventing Prolonged Ileus, Anastomotic Leaks Could Reduce Readmissions in CRC

Julia Bonavitacola
Patients with colorectal cancer (CRC) had reduced readmissions when treatment focused on preventing prolonged ileus, increasing the use of minimally invasive surgery, and preventing anastomotic leaks.
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
December 18th 2023

Adjuvant Chemotherapy Could Improve Prognosis in Patients With CRC

Julia Bonavitacola
Patients aged 80 years and older with colorectal cancer (CRC) could have an improved prognosis at the completion of adjuvant chemotherapy.
Chemotherapy Toxicities in Nonmetastatic CRC Associated With Low Skeletal Muscle
December 14th 2023

Chemotherapy Toxicities in Nonmetastatic CRC Associated With Low Skeletal Muscle

Julia Bonavitacola
Skeletal muscle proved to be significant in calculating chemotherapy toxicities in nonmetastatic colorectal cancer (CRC).
Colorectal cancer screening | Image credit: © Orawan - stock.adobe.com
December 12th 2023

Perforation Not Necessarily Poor Prognostic Factor in Patients With Metastatic CRC

Julia Bonavitacola
Patients with metastatic colorectal cancer (CRC) who experience colon perforation may have similar survival times to those without perforation.
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