Colorectal Cancer

Latest News
July 31st 2025

High Adenoma Detection Rates Linked to Lower CRC Rates, Worse Survival

July 30th 2025

Patients Support Personalized Follow-Up After Colon Cancer Surgery, Study Finds

July 29th 2025

Machine Learning Predicts 5-Year Survival in Stage III CRC

July 16th 2025

Colon Age Tool Assesses Early-Onset Colorectal Cancer Risk in Male Veterans

July 14th 2025

Colorectal Cancer Shared Care Model Gains Support From Clinicians

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June 10th 2025

Exploring Amivantamab's Potential in Colorectal Cancer: Dirk Arnold, MD, PhD

March 13th 2025

The Importance of Early Screening, Biomarker Testing, and Support in Colorectal Cancer Care

February 18th 2025

Tackling Colorectal Cancer Care Inequities Through Patient Advocacy Groups

February 7th 2025

Patients With Colorectal Cancer Seek More Say in Treatment, Face Financial Barriers

October 21st 2024

A Look at Cancers Where Biomarkers Are Needed

May 24th 2024

Dr Ajay Goel Explains Effectiveness of Liquid Biopsies, Tissue-Based Biomarkers in Treating CRC

May 21st 2024

Dr Ajay Goel Discusses New Methods of Testing for EOCRC, Recurrence

August 28th 2023

Botensilimab and Balstilimab in Refractory Microsatellite Stable (MSS) mCRC

August 21st 2023

Impact of Microsatellite Stability in Metastatic Colorectal Cancer

April 4th 2023

Utilizing RWE to Address Unmet Needs for CRC

More News

Metformin | Image credit: luchschenF - stock.adobe.com
July 1st 2025

Metformin May Boost PFS in Patients With Metastatic Colorectal Cancer, Study Finds

Pearl Steinzor
Metformin use may enhance progression-free survival (PFS) in patients receiving first-line systemic therapy for patients with metastatic colorectal cancer.
Colorectal cancer awareness | Image credit: Jo Panuwat D - stock.adobe.com
June 27th 2025

5 Reasons Why Colorectal Cancer May Be Rising in Young Adults

Pearl Steinzor
Why is colorectal cancer affecting more young people, and what can be done to prevent it?
Affordable Care Act | Image credit: Yauhen - stock.adobe.com
June 20th 2025

Many Still Pay for Colonoscopy Prep Despite ACA Coverage Mandate

Pearl Steinzor
Widespread noncompliance with federal cost-sharing rules exists, particularly impacting Medicare beneficiaries and patient-preferred prep options, study finds.
ctDNA analysis | Image credit: Thaweechai - stock.adobe.com
June 18th 2025

ctDNA Response Predicts Outcomes in MSI-H mCRC Immunotherapy

Pearl Steinzor
Early circulating tumor DNA (ctDNA) changes predict survival in mismatch repair or microsatellite instability–high (dMMR/MSI-H) metastatic colorectal cancer (mCRC) treated with immune checkpoint inhibitors (ICIs).
FIT test CRC - Paul Maguire - stock.adobe.com
June 12th 2025

Starting Colorectal Cancer Screening at Age 40 Cuts Death Risk by 39%, Study Finds

Pearl Steinzor
Initiating fecal immunochemical test (FIT) screening before age 50 can significantly reduce colorectal cancer incidence and mortality, according to one study.
Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com
June 6th 2025

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

Rose McNulty
Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the CHALLENGE study recommended.
CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
June 3rd 2025

Blood Test Detects 79% of Colorectal Cancers in Screening Study

Pearl Steinzor
A circulating tumor DNA (ctDNA) blood test demonstrated high sensitivity and specificity for colorectal cancer (CRC) detection in a large average-risk population, study finds.
The authors emphasized the need for further research into improving the diagnostic performance of both blood- and stool-based tests, particularly to enhance early lesion detection. | Image credit: SewcreamStudio - stock.adobe.com
May 31st 2025

FIT Outperforms Blood-Based cfDNA Test in Detecting Precancerous Colorectal Lesions

Rose McNulty
Fecal immunochemical testing (FIT) was more accurate than blood-based testing for detecting advanced precancerous colorectal lesions, a comparative study found.
colorectal cancer | Image credit: Rasi - stock.adobe.com
May 30th 2025

Immune-Based Risk Score Shows Strong Predictive Value for CRC Outcomes

Skylar Jeremias
A novel machine learning model enhances colorectal cancer (CRC) prognosis and immunotherapy response prediction by integrating clinical data and immune gene expression.
CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
May 28th 2025

Comorbidities Linked to Emergency Colon Cancer Diagnoses, Study Finds

Pearl Steinzor
Patients with chronic conditions are less likely to be diagnosed via screening and face higher mortality when cancer is detected in emergency settings, according to one study.
ChatGPT | Image credit: irissca - stock.adobe.com
May 16th 2025

ChatGPT Effectively Answers Patient Questions on CRC Screening

Pearl Steinzor
Study findings show ChatGPT-4o provides accurate, complete, and trustworthy responses to patient-generated colorectal cancer (CRC) screening questions.
AJMC
May 15th 2025

Navigation and Clinician Payment Investments Enhance Colorectal Cancer Screening Benefits

Portia J. Zaire, PhD, RN A. Mark Fendrick, MD Jacob E. Kurlander, MD, MS Archana Radhakrishnan, MD, MHS
Investing in patient navigation and clinician incentives ensures colorectal cancer screening completion, improves early detection, reduces disparities, achieves cost savings, and advances population health for all stakeholders.
Health equity | Image credit: Rochu_2008 - stock.adobe.com
May 8th 2025

Racial Disparities Exist in Colorectal Cancer Deaths

Pearl Steinzor
Ongoing mortality gaps persist among Black and American Indian/Alaska Native patients with colorectal cancer, despite some overall improvements.
Anatomy of colon model | Image credit: M+Isolation+Photo - stock.adobe.com
April 24th 2025

TyG-BMI Index Predicts Colorectal Cancer Risk, Study Finds

Pearl Steinzor
A new analysis links higher triglyceride-glucose (TyG) and TyG–body mass index (TyG-BMI) levels to increased colorectal cancer (CRC) risk, especially among women, but not mortality.
Vitamin D | Image credit: Galina Zhigalova - stock.adobe.com
April 23rd 2025

Vitamin D’s Potential Role in Colorectal Cancer Prevention, Immune Health

Pearl Steinzor
Emerging research highlights how vitamin D boosts immunity and reduces colorectal cancer (CRC) risk by regulating inflammation and cell growth.
Cancer detection | Image credit: lordn - stock.adobe.com
April 17th 2025

Colorectal, Pancreatic Cancer Rising in Younger Adults

Pearl Steinzor
There has been a sharp increase in colorectal and pancreatic cancer rates among Americans under 55 years, despite declines in older adults, according to a new study.
Hurricane Irma | Image credit: Satoshi Kina - stock.adobe.com
April 14th 2025

Disasters Likely Cause Delays in Early Colorectal Cancer Diagnosis

Pearl Steinzor
Findings from a new study reveal how hurricanes and the pandemic disrupted colorectal cancer (CRC) screenings in Puerto Rico, leading to a rise in late-stage diagnoses.
FDA approved. | Image Credit: Pawel - stock.adobe.com
April 8th 2025

Nivolumab Plus Ipilimumab FDA Approved for MSI-H, dMMR Colorectal Cancer

Pearl Steinzor
The combination of nivolumab with ipilimumab was approved for unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer.
FIT outreach | Image credit: Rix Pix - stock.adobe.com
April 8th 2025

Mailed FIT Outreach Boosts CRC Screening in Medicaid Patients, Study Finds

Pearl Steinzor
Patient navigation and mailed outreach improved colorectal cancer screening rates in rural clinics, but follow-up colonoscopy participation remains low.
Immune checkpoint protein | Image credit: Corona Borealis - stock.adobe.com
March 20th 2025

Data Highlights Factors Impacting Immune Checkpoint Inhibitors in mCRC

Pearl Steinzor
Clinical characteristics were associated with different survival outcomes in patients treated with immune checkpoint inhibitor–based therapy.
Aging | Image credit: smolaw11 - stock.adobe.com
March 11th 2025

Biological Aging Linked to Colorectal Cancer Risk Regardless of Gender

Pearl Steinzor
Biological age, rather than chronological age, may be a stronger predictor of colorectal cancer risk—especially in older adults.
US Supreme Court | Image credit: Craig - stock.adobe.com
March 7th 2025

Supreme Court Case Could Threaten Free Colorectal Cancer Screenings

Pearl Steinzor
The American College of Gastroenterology warns millions may lose access to life-saving colorectal cancer screenings.
Colorectal Cancer Awareness Month | Image credit: ananaline - stock.adobe.com
March 7th 2025

5 Things to Know About Colorectal Cancer

Pearl Steinzor
Here are key facts, risk factors, and life-saving screening recommendations for colorectal cancer prevention and treatment.
Colonoscopy | Image credit: shevchukandrey - stock.adobe.com
March 4th 2025

Updated Guidelines Refine Best Practices for Colonoscopy Bowel Prep

Pearl Steinzor
The US Multi-Society Task Force updates 2014 recommendations, emphasizing split-dose prep, diet flexibility, and quality tracking.
Blue cancer ribbon | Image credit: Chinnapong - stock.adobe.com
February 26th 2025

Cetuximab Plus Chemotherapy May Improve Colorectal Cancer Outcomes

Pearl Steinzor
When combined with chemotherapy, cetuximab shows promising efficacy for optimizing treatment strategies for patients with metastatic colorectal cancer.
Yogurt | Image credit: pilipphoto - stock.adobe.com
February 24th 2025

Eating Yogurt May Help Reduce Colorectal Cancer Risk

Pearl Steinzor
People who regularly consumed yogurt had lower rates of colorectal cancer–positive Bifidobacterium.
CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
February 21st 2025

Specialists Boost Patient Acceptance of Longer Colonoscopy Intervals

Pearl Steinzor
Study results show most patients prefer more frequent colonoscopies, but specialist recommendations drive acceptance of extended intervals.
Calcium sources | Image credit: tima-miroshnichenko - pexels.com
February 17th 2025

Calcium Intake Linked to Reduced Colorectal Cancer Risk, Study Finds

Pearl Steinzor
Higher calcium intake was associated with reduced colorectal cancer risk across tumor sites and calcium sources, according to one study.
Colorectal cancer | Image credit: mi_viri - stock.adobe.com
February 12th 2025

Evaluation System Reduces Ineffective Hospital Days in Colorectal Cancer Care

Pearl Steinzor
Researchers have developed an evaluation protocol index to optimize postoperative recovery.
Flatiron Health, Exact Sciences Announce Deal to Speed Evidence Generation With MRD Test
February 6th 2025

Flatiron Health, Exact Sciences Announce Deal to Speed Evidence Generation With MRD Test

AJMC Staff
The companies announced the deal in a statement February 5, 2025, noting that the first patient had enrolled in a prospective clinical study using the test to monitor cancer recurrence across multiple solid tumor types.
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