Colorectal Cancer

Latest News

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Genomic Profiling in Colorectal Cancer Reveals Prognostic Markers

September 11th 2025

Next-generation sequencing shows limited survival benefit but identifies key mutations that may inform future treatment strategies.

CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
Improving Colorectal Cancer Prognosis With Tumor Deposit-Based N-Staging

September 9th 2025

Rideshare | Image credit: terovesalainen - stock.adobe.com
Rideshare Cuts Colon Cancer Deaths, Saves Costs After Abnormal FIT, Study Finds

September 4th 2025

CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
AI Model Using EHR Data Predicts 5-Year Survival in Colorectal Cancer

August 19th 2025

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Comfort, Targeted Nursing Boost Recovery in Colorectal Surgery

August 18th 2025

More News

Aging | Image credit: smolaw11 - stock.adobe.com
March 11th 2025

Biological Aging Linked to Colorectal Cancer Risk Regardless of Gender

Pearl Steinzor
Biological age, rather than chronological age, may be a stronger predictor of colorectal cancer risk—especially in older adults.
US Supreme Court | Image credit: Craig - stock.adobe.com
March 7th 2025

Supreme Court Case Could Threaten Free Colorectal Cancer Screenings

Pearl Steinzor
The American College of Gastroenterology warns millions may lose access to life-saving colorectal cancer screenings.
Colorectal Cancer Awareness Month | Image credit: ananaline - stock.adobe.com
March 7th 2025

5 Things to Know About Colorectal Cancer

Pearl Steinzor
Here are key facts, risk factors, and life-saving screening recommendations for colorectal cancer prevention and treatment.
Colonoscopy | Image credit: shevchukandrey - stock.adobe.com
March 4th 2025

Updated Guidelines Refine Best Practices for Colonoscopy Bowel Prep

Pearl Steinzor
The US Multi-Society Task Force updates 2014 recommendations, emphasizing split-dose prep, diet flexibility, and quality tracking.
Blue cancer ribbon | Image credit: Chinnapong - stock.adobe.com
February 26th 2025

Cetuximab Plus Chemotherapy May Improve Colorectal Cancer Outcomes

Pearl Steinzor
When combined with chemotherapy, cetuximab shows promising efficacy for optimizing treatment strategies for patients with metastatic colorectal cancer.
Yogurt | Image credit: pilipphoto - stock.adobe.com
February 24th 2025

Eating Yogurt May Help Reduce Colorectal Cancer Risk

Pearl Steinzor
People who regularly consumed yogurt had lower rates of colorectal cancer–positive Bifidobacterium.
CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
February 21st 2025

Specialists Boost Patient Acceptance of Longer Colonoscopy Intervals

Pearl Steinzor
Study results show most patients prefer more frequent colonoscopies, but specialist recommendations drive acceptance of extended intervals.
Calcium sources | Image credit: tima-miroshnichenko - pexels.com
February 17th 2025

Calcium Intake Linked to Reduced Colorectal Cancer Risk, Study Finds

Pearl Steinzor
Higher calcium intake was associated with reduced colorectal cancer risk across tumor sites and calcium sources, according to one study.
Colorectal cancer | Image credit: mi_viri - stock.adobe.com
February 12th 2025

Evaluation System Reduces Ineffective Hospital Days in Colorectal Cancer Care

Pearl Steinzor
Researchers have developed an evaluation protocol index to optimize postoperative recovery.
Flatiron Health, Exact Sciences Announce Deal to Speed Evidence Generation With MRD Test
February 6th 2025

Flatiron Health, Exact Sciences Announce Deal to Speed Evidence Generation With MRD Test

AJMC Staff
The companies announced the deal in a statement February 5, 2025, noting that the first patient had enrolled in a prospective clinical study using the test to monitor cancer recurrence across multiple solid tumor types.
United by Unique | Image credit: UICC
February 4th 2025

On World Cancer Day, NCCN Patient Advocates Share What Makes Their Journeys Unique

Mary Caffrey
World Cancer Day also marks the start of the ‘United by Unique’ campaign, which seeks to highlight how each person’s journey with cancer is unique, even though the patients, caregivers, and health care teams who are touched by cancer are united by shared goals.
Colorectal cancer - mi_viri - stock.adobe.com.
February 4th 2025

How Prior Malignancy Impacts Survival in Metastatic Colorectal Cancer

Pearl Steinzor
New data showed that prior malignancy may influence survival outcomes in patients with metastatic colorectal cancer, highlighting the need for standardized treatment approaches.
CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
January 23rd 2025

Unlocking Early Colorectal Cancer Detection With Artificial Intelligence

Pearl Steinzor
With high-sensitivity and strong negative predictive value, this artificial intelligence (AI)-powered tool enhances early colorectal cancer (CRC) detection and risk stratification in primary care.
Waist circumference measurement | Image credit: thatinchan - stock.adobe.com
January 21st 2025

Obesity Metrics May Better Reflect CRC Link Than BMI

Pearl Steinzor
Waist circumference and waist-to-hip ratio show stronger links to colorectal cancer (CRC) than body mass index (BMI), a new study has found.
FDA Approved
January 17th 2025

FDA Approves Sotorasib Plus Panitumumab for KRAS G12C-Mutated Metastatic CRC

Julia Bonavitacola
The combination treatment specifically targets KRAS-mutated metastatic colorectal cancer (CRC) to improve progression-free survival.
Blood sample collection | Image credit: luchschenF - stock.adobe.com
January 16th 2025

Prioritizing Blood-Based Colorectal Cancer Tests May Lead to Higher Costs, Worse Outcomes

Pearl Steinzor
Despite the availability of several noninvasive tests for colorectal cancer, prioritizing blood-based tests may result in higher costs and worse population-level outcomes.
CRC concept | Image credit: SewcreamStudio - stock.adobe.com
January 13th 2025

Ethnic Disparities Identified in Colorectal Cancer Diagnoses, Study Finds

Pearl Steinzor
New research examines how ethnicity impacts colorectal cancer diagnosis, early-onset colorectal cancer (CRC) prevalence, and stage at diagnosis.
Colorectal cancer | Image credit: mi_viri - stock.adobe.com
January 9th 2025

Limited Benefits of ctDNA Testing in Colorectal Cancer Surveillance, Study Finds

Pearl Steinzor
Adding serial circulating tumor DNA (ctDNA) assays to standard of care imaging surveillance had limited clinical benefits in patients with resected colorectal cancer (CRC).
FIT test CRC - Paul Maguire - stock.adobe.com
January 6th 2025

When to Stop Colorectal Cancer Screening?

Pearl Steinzor
How does age, sex, comorbidity, and screening history influence the cost-effectiveness of continuing colorectal cancer (CRC) screening in older adults?
Top 5 CRC Articles of 2024
December 27th 2024

Top 5 Most-Read Colorectal Cancer Articles of 2024

Julia Bonavitacola
The most-read articles focused on the new colonoscopy guidelines, the relationship between diabetes and colorectal cancer, and the rate of colonoscopies performed.
FDA Approved
December 20th 2024

FDA Approves Encorafenib With Cetuximab and mFOLFOX6 for Metastatic CRC

Julia Bonavitacola
Patients with the BRAF V600E mutation and metastatic colorectal cancer (CRC) can be treated with a combination of encorafenib with cetuximab and mFOLFOX6.
Colorectal cancer | Image credit: SewcreamStudio - stock.adobe.com
December 18th 2024

Bevacizumab Biosimilar Equally Effective in Metastatic Colorectal Cancer

Julia Bonavitacola
Compared with originator bevacizumab, the biosimilar version of bevacizumab had equal efficacy when used to treat metastatic colorectal cancer.
Top 5 News Articles 2024
December 16th 2024

Top 5 Most-Read News Articles of 2024

Julia Bonavitacola
In 2024, the most-read news articles published on the website of The American Journal of Managed Care® included FDA approvals, colonoscopy guidelines, and a list of drugs facing shortages.
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
December 13th 2024

Treatment Combinations Based in Immune Checkpoint Inhibitors Provide Survival Benefits in CRC

Julia Bonavitacola
Patients with heavily pretreated microsatellite stable metastatic colorectal cancer (CRC) had survival benefits after using combinations based in immune checkpoint inhibitors.
Stool test | Image credit: luchschenF - stock.adobe.com
December 10th 2024

Mass-Mailed Stool Tests Helped Improve Odds of Adherence, CRC Test Return

Julia Bonavitacola
Older adults on Medicare Advantage had improved adherence and odds of a test return when a stool test was mailed to them for screening of colorectal cancer (CRC).
Rectal cancer | Image credit: Anatomy Insider - stock.adobe.com
December 6th 2024

Rectal Cancer Has Better Short-Term Outcomes With Robotic Abdominoperineal Resection

Julia Bonavitacola
Laparoscopic abdominoperineal resection had worse short-term outcomes when compared with robotic resection, according to a review.
Respiratory system | Image credit: PIC4U - stock.adobe.com
December 2nd 2024

CRC Incidence Risk Associated With Changes in Cardiorespiratory Fitness

Julia Bonavitacola
Changes in cardiorespiratory fitness from youth to adulthood was associated with colorectal cancer (CRC) incidence risk.
Colorectal cancer | Image credit: Sebastian Kaulitzki - stock.adobe.com
November 25th 2024

Racial, Ethnic Disparities Persist in Mortality for Patients With Early-Onset CRC

Julia Bonavitacola
Native Hawaiian and non-Hispanic Black individuals had the highest burden of mortality among patients with early-onset colorectal cancer (CRC).
VUMC logo | Image: VUMC
November 21st 2024

Innovating Cancer Care Through Equity and AI: Vanderbilt’s Vision

Maggie L. Shaw
Coverage from the IVBM event with Vanderbilt-Ingram Cancer Center in Nashville, Tennessee.
FIT | Image credit: Paul Maguire - stock.adobe.com
November 19th 2024

Commercial FIT Capable of Similar Diagnostic Results as New Stool DNA Test

Julia Bonavitacola
Lowering the positivity threshold for a high-quality fecal immunochemical test (FIT) can increase sensitivity of noninvasive screening for colorectal cancer in a more economical way.
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