Colorectal Cancer

Latest News

ctDNA analysis | Image credit: Thaweechai - stock.adobe.com
ctDNA Response Predicts Outcomes in MSI-H mCRC Immunotherapy

June 18th 2025

Early circulating tumor DNA (ctDNA) changes predict survival in mismatch repair or microsatellite instability–high (dMMR/MSI-H) metastatic colorectal cancer (mCRC) treated with immune checkpoint inhibitors (ICIs).

FIT test CRC - Paul Maguire - stock.adobe.com
Starting Colorectal Cancer Screening at Age 40 Cuts Death Risk by 39%, Study Finds

June 12th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com
Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

June 6th 2025

CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
Blood Test Detects 79% of Colorectal Cancers in Screening Study

June 3rd 2025

The authors emphasized the need for further research into improving the diagnostic performance of both blood- and stool-based tests, particularly to enhance early lesion detection. | Image credit: SewcreamStudio - stock.adobe.com
FIT Outperforms Blood-Based cfDNA Test in Detecting Precancerous Colorectal Lesions

May 31st 2025

More News

FIT test CRC - Paul Maguire - stock.adobe.com
January 6th 2025

When to Stop Colorectal Cancer Screening?

Pearl Steinzor
How does age, sex, comorbidity, and screening history influence the cost-effectiveness of continuing colorectal cancer (CRC) screening in older adults?
Top 5 CRC Articles of 2024
December 27th 2024

Top 5 Most-Read Colorectal Cancer Articles of 2024

Julia Bonavitacola
The most-read articles focused on the new colonoscopy guidelines, the relationship between diabetes and colorectal cancer, and the rate of colonoscopies performed.
FDA Approved
December 20th 2024

FDA Approves Encorafenib With Cetuximab and mFOLFOX6 for Metastatic CRC

Julia Bonavitacola
Patients with the BRAF V600E mutation and metastatic colorectal cancer (CRC) can be treated with a combination of encorafenib with cetuximab and mFOLFOX6.
Colorectal cancer | Image credit: SewcreamStudio - stock.adobe.com
December 18th 2024

Bevacizumab Biosimilar Equally Effective in Metastatic Colorectal Cancer

Julia Bonavitacola
Compared with originator bevacizumab, the biosimilar version of bevacizumab had equal efficacy when used to treat metastatic colorectal cancer.
Top 5 News Articles 2024
December 16th 2024

Top 5 Most-Read News Articles of 2024

Julia Bonavitacola
In 2024, the most-read news articles published on the website of The American Journal of Managed Care® included FDA approvals, colonoscopy guidelines, and a list of drugs facing shortages.
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
December 13th 2024

Treatment Combinations Based in Immune Checkpoint Inhibitors Provide Survival Benefits in CRC

Julia Bonavitacola
Patients with heavily pretreated microsatellite stable metastatic colorectal cancer (CRC) had survival benefits after using combinations based in immune checkpoint inhibitors.
Stool test | Image credit: luchschenF - stock.adobe.com
December 10th 2024

Mass-Mailed Stool Tests Helped Improve Odds of Adherence, CRC Test Return

Julia Bonavitacola
Older adults on Medicare Advantage had improved adherence and odds of a test return when a stool test was mailed to them for screening of colorectal cancer (CRC).
Rectal cancer | Image credit: Anatomy Insider - stock.adobe.com
December 6th 2024

Rectal Cancer Has Better Short-Term Outcomes With Robotic Abdominoperineal Resection

Julia Bonavitacola
Laparoscopic abdominoperineal resection had worse short-term outcomes when compared with robotic resection, according to a review.
Respiratory system | Image credit: PIC4U - stock.adobe.com
December 2nd 2024

CRC Incidence Risk Associated With Changes in Cardiorespiratory Fitness

Julia Bonavitacola
Changes in cardiorespiratory fitness from youth to adulthood was associated with colorectal cancer (CRC) incidence risk.
Colorectal cancer | Image credit: Sebastian Kaulitzki - stock.adobe.com
November 25th 2024

Racial, Ethnic Disparities Persist in Mortality for Patients With Early-Onset CRC

Julia Bonavitacola
Native Hawaiian and non-Hispanic Black individuals had the highest burden of mortality among patients with early-onset colorectal cancer (CRC).
VUMC logo | Image: VUMC
November 21st 2024

Innovating Cancer Care Through Equity and AI: Vanderbilt’s Vision

Maggie L. Shaw
Coverage from the IVBM event with Vanderbilt-Ingram Cancer Center in Nashville, Tennessee.
FIT | Image credit: Paul Maguire - stock.adobe.com
November 19th 2024

Commercial FIT Capable of Similar Diagnostic Results as New Stool DNA Test

Julia Bonavitacola
Lowering the positivity threshold for a high-quality fecal immunochemical test (FIT) can increase sensitivity of noninvasive screening for colorectal cancer in a more economical way.
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
November 11th 2024

Smoking a Risk Factor for CRC in Black African Patients

Julia Bonavitacola
Risk factors of colorectal cancer (CRC) include both smoking and a combination of smoking and alcohol in African patients.
CRC | Image credit: mi_viri - stock.adobe.com
November 7th 2024

Disparities Persist in CRC Screening, Management Between High-, Low-Income Countries

Julia Bonavitacola
Low- and high-income countries had significant disparities in screening for colorectal cancer (CRC) due to limited access to screening and treatment in low-income countries.
Colorectal cancer | Image credit: Sebastian Kaulitzki - stock.adobe.com
November 5th 2024

Overall, Progression-Free Survival in Colon Cancer Indicated Through Visceral Proteins

Julia Bonavitacola
Ratios of visceral proteins can act as independent indicators for both overall and progression-free survival in patients with colon cancer.
Jeffrey Reese Contributor
November 4th 2024

Contributor: An Urgent Call to Action as Colorectal Cancer Rates Skyrocket Among Young People

Jeffrey Reese
As rates of CRC skyrocket in young individuals, means of addressing the growing problem must be considered.
Blood test | Image credit: angellodeco - stock.adobe.com
October 29th 2024

Net Results Vary When Using Cell-Free DNA Blood Tests for CRC Screening

Julia Bonavitacola
Results could vary between having a net benefit or harm based on the balance between achieving screening in individuals who otherwise wouldn’t and using cell-free DNA blood tests in favor of more effective methods of screening for colorectal cancer (CRC).
Robot-assisted surgery | Image credit: Monopoly919 - stock.adobe.com
October 25th 2024

Robotic Systems Possess Positive Outcomes, Safety in Colorectal Surgery

Julia Bonavitacola
Surgery for colorectal cancer has been both positive and challenging when using robotic-assisted surgeries.
Fecal immunochemical test | Image credit: Paul Maguire - stock.adobe.com
October 22nd 2024

FIT Completion, Yield Rates in CRC Screening Similar After New Screening Guidelines

Julia Bonavitacola
Patients were found to have similar completion and yield rates for the fecal immunochemical test (FIT) at both 45 years and 50 years, making screening for colorectal cancer (CRC) effective in younger patients.
Calculating cost | Image credit: joyfotoliakid - stock.adobe.com
October 10th 2024

Cost Effectiveness Varies in TAS-102 Plus Bevacizumab Third Line Treatment

Julia Bonavitacola
Patients with refractory metastatic colorectal cancer could use trifluridine/tipiracil (TAS-102) plus bevacizumab as a cost effective third line treatment in China but the same was not found in the United States and United Kingdom.
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
October 7th 2024

CRC Screening Increases in Patients Aged 45 to 49 After USPSTF Recommendation

Julia Bonavitacola
The updated guidelines from the US Preventive Services Task Force (USPSTF) have led to an increase in screening for colorectal cancer (CRC) in individuals aged 45 to 49 years.
Doctor talking to older adult | Image credit: rocketclips - stock.adobe.com
October 4th 2024

Preference for CRC Testing Associated With Anticipated Decision Regret, Medical Maximizing

Julia Bonavitacola
Increased time spent on discussing testing for colorectal cancer (CRC) was associated with patient satisfaction in older adults.
Colorectal cancer | Image credit: Orawan - stock.adobe.com
October 1st 2024

Ultrasound Method Linked With Improved Survival in Patients With CRC Liver Metastases

Julia Bonavitacola
Patients with colorectal cancer (CRC) liver metastases had reduced risk of intrahepatic recurrence when using intraoperative contrast-enhanced ultrasounds.
Sleep | Image credit: terovesalainen - stock.adobe.com
September 24th 2024

Proper Sleep Duration, Ease of Getting Up Protective Against CRC

Julia Bonavitacola
Colorectal cancer (CRC) could be affected by various factors involved in sleep, including snoring.
Colorectal cancer | Image credit: Sebastian Kaulitzki - stock.adobe.com
September 17th 2024

OS Disparity, Driver Gene Variations by Race and Ethnicity Seen in CRC

Julia Bonavitacola
A substantial overall survival (OS) disparity by race and ethnicity was found in patients with colorectal cancer (CRC), with socioeconomic status and tumor molecular features largely contributing to the difference in OS.
Colorectal cancer | Image credit: mi_viri - stock.adobe.com
September 12th 2024

Updated Colonoscopy Guidelines Have Implications on Doctors, Patients Alike

Julia Bonavitacola
An update to the colonoscopy guidelines released by the American College of Gastroenterology and the American Society for Gastrointestinal Endoscopy could have implications on how colonoscopies are measured in the future.
Rectal cancer | Image credit: Anatomy Insider - stock.adobe.com
September 10th 2024

Quality of Life Lower in Patients Without Rectal Cancer Recurrence Receiving Radiotherapy

Julia Bonavitacola
Patients who received radiotherapy without a recurrence of rectal cancer had significantly lower quality of life compared with patients who did not receive radiotherapy.
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
September 4th 2024

Low Mortality Rates Found After CRC Surgery by Recently Trained Physicians

Julia Bonavitacola
Educational principles implemented after 1998 may have led to lower mortality rates in patients with colorectal cancer (CRC) receiving care from doctors trained after that point.
Blood test | Image credit: angellodeco - stock.adobe.com
August 28th 2024

Clinical Potential Found in Multiomics Liquid Biopsy for CRC Detection

Julia Bonavitacola
Early-stage detection of colorectal cancer (CRC) could be achieved using a noninvasive multiomics liquid biopsy test, according to a recent study.
Endoscopy | Image credit: romaset - stock.adobe.com
August 22nd 2024

New Recommendations, Quality Indicators for Colonoscopy Released

Julia Bonavitacola
The new guidelines are another method of keeping a high-quality standard for colorectal cancer screening.
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