The AJMC® Multiple Sclerosis compendium is a comprehensive resource for clinical news and expert insights for the disabling disease that impacts the brain and spinal cord.
May 8th 2024
A prospective study found evidence of serum neurofilament light (sNfL) level increases in patients affected by active forms of relapsing-remitting multiple sclerosis (RRMS); however, these findings were not significant enough to suggest sNfL measurements replace clinical or MRI monitoring of disease activity.
Strategies for the Management and Treatment of ALS: The Value of Early Diagnosis and Clinical Intervention
3.0 Credits / Neurology
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Advancing Targeted Therapies Aimed at Smoldering Disease in Multiple Sclerosis
June 27, 2024 | 1:00 PM & 7:00 PM ET
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Leveraging Managed Care to Optimize Best Practices in the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
1.0 Credit / Neurology
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Improving Outcomes and Quality of Care in Spinal Muscular Atrophy: Updates in Treatment Advances
2.0 Credits / Neurology
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New and Emerging Treatment Strategies for Myasthenia Gravis: The Role of the Specialty Pharmacist
1.0 Credit / Neurology
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Improving Treatment Access for Spinal Muscular Atrophy: How Managed Care Strategies Can Ease Clinical and Caregiver Burden
1.5 Credits / Neurology
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Assessing the Treatment Landscape for Multiple Sclerosis to Better Individualize Care
1.5 Credits / Neurology
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Identifying Standards for Timely Intervention and Treatment in Multiple Sclerosis
January 23rd 2019Prompt diagnosis and timely intervention is key in improving outcomes for patients with multiple sclerosis (MS). A new study in Multiple Sclerosis Journal outlines quality standards for timely, brain health–focused MS care.
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Researchers Use Blood Test to Detect Preclinical Alzheimer Disease Signs
January 21st 2019Researchers used a blood test to look for biomarkers indicative of Alzheimer disease in a group of people with a genetic mutation for a familial form of the disease, and they said the test can predict differences about 16 years before affected patients are expected to begin showing symptoms. The hope is that a blood test could one day be used to identify brain disease for not only Alzheimer disease but also other neurodegenerative conditions, such as multiple sclerosis, traumatic brain injury, or stroke.
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Could Coffee and Caffeine Treat Fatigue in Patients With MS?
January 12th 2019Researchers hypothesized that because coffee and caffeine showed a beneficial effect on daytime tiredness in Parkinson disease, a similar positive effect might be assumed in multiple sclerosis (MS). Investigators compiled a systematic review focused on summarizing the possible effects of coffee and caffeine in MS.
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Ocrelizumab Reduces Progression of Upper Extremity Impairment in Primary Progressive MS
January 8th 2019For patients with multiple sclerosis (MS), upper extremity (UE) impairment is not uncommon, and patients with primary progressive MS tend to have a higher prevalence of UE dysfunction and greater impairment.
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Perceptions of Patients With MS and Caregivers on Daily Activity Performance
January 3rd 2019An evaluation of cognitive function measurements, performance in daily activities, and the perception of cognitive functions in patients with multiple sclerosis (MS) found caregiver perceptions more closely correlate with the test measurements than patient perceptions.
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Genetic Risk Variant Tied to Type of CNS Cell Increases Risk of MS, Study Says
December 29th 2018A genetic risk variant, rs7665090G, located near NFKB1, on astrocytes enhances the accessibility of the central nervous system (CNS) to peripheral immune cells, escalating the risk of autoimmune inflammation and multiple sclerosis (MS), according to the results of a recent study.
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Switching Patients With MS Who Are Stable on Interferon β Has Suboptimal Outcomes
December 29th 2018Patients with multiple sclerosis (MS) who are stable on an interferon β (INFβ) should remain on that therapy rather than switching to another INFβ, according to a study in ClinicoEconomics and Outcomes Research.
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Researchers Identify New, Overlooked Target to Treat Multiple Sclerosis
December 27th 2018Mature oligodendrocytes have been overlooked in the past as a way to treat multiple sclerosis, but a new study has found they might be able to help with remyelinating axons the same as new oligodendrocytes.
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Food Allergies Associated With More Relapses in Patients With MS
December 21st 2018Patients with multiple sclerosis (MS) who also have food allergies have more relapses than patients with no known food allergy, according to a new study published in the Journal of Neurology, Neurosurgery & Psychiatry.
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FDA Warns of Rare Risks of MS Drug Alemtuzumab
December 20th 2018The FDA has issued a warning that rare but serious cases of stroke and tears in the lining of arteries in the head and neck have occurred in patients with multiple sclerosis (MS) who received treatment with alemtuzumab (Lemtrada).
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CDC Launching Surveillance System to Study Multiple Sclerosis, Other Neurological Conditions
December 14th 2018With $5 million appropriated from Congress, CDC is launching a National Neurological Conditions and Surveillance System to help increase understanding of neurological disorders and to further support neurologic research, starting with multiple sclerosis and Parkinson disease.
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International Consensus on Timely Care for Multiple Sclerosis
December 7th 2018Multiple sclerosis (MS) is a progressive neurological disease that requires timely management, and a panel of neurologists has developed an internationally applicable standard of care for timely management in patients with MS.
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Patients Who Stop Taking Gilenya May Experience Worsening of Multiple Sclerosis
December 4th 2018The FDA has issued a safety warning that patients who stopped taking Gilenya experienced worsening of multiple sclerosis, compared with before treatment started or during treatment, in rare cases.
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Sex Hormones May Play an Important Role in Multiple Sclerosis Prevalence and Development
September 29th 2018In a review of sex hormones and their role in the development of multiple sclerosis (MS), Ysrraelit and Correale compiled multiple references to provide clinical details regarding hormones and their respective immunological mechanisms.
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Researchers Tout Behavioral Science to Increase Physical Activity in Patients With MS
September 21st 2018Noting a disconnect between evidence of benefit and uptake of exercise in patients with multiple sclerosis (MS), researchers offer behavioral science, specifically Social Cognitive Theory, as an approach to increasing participation.
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MS-SMART: First Multiarm Efficacy Trial in Progressive MS
September 20th 2018The Multiple Sclerosis-Secondary Progressive Multi-Arm Randomization Trial (MS-SMART) is the first multiarm trial designed specifically to address the unmet need for further identification of neuroprotective drugs in secondary progressive multiple sclerosis.
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B Cell–Mediated T Cell Proliferation Important for MS Pathogenesis
September 15th 2018A recent study has discovered that B cells mediate spontaneous T cell proliferation through the HLA-DR15 haplotype, and this interaction between T cells and B cells may serve as a key factor in understanding the pathogenesis of multiple sclerosis (MS).
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