Oncology

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Tarlatamab Safety Varies Between Clinical and Real-World SCLC Trials

By Hayden E. Klein

May 6th 2025

The bispecific T-cell engager tarlatamab demonstrated favorable antitumor activity in a small cohort with small cell lung cancer (SCLC), but it was also linked to higher rates of serious adverse events like cytokine release syndrome than seen in clinical trials.

CureCancer | Image Credit: © MMPhoto21-sotck.adobe.com

COA 2025: Insight, Innovation, and Independent Strength

By Maggie L. Shaw

May 5th 2025

Community Oncology Reacts to Trump's Drug Pricing Executive Order

By Maggie L. Shaw

May 2nd 2025

Melanoma & Skin Cancer Awareness Month | Image credit: Waseem Ali Khan - stock.adobe.com

5 Things You Should Know About Skin Cancer

By Pearl Steinzor

May 2nd 2025

stethoscopewithcompass | Image Credit: © Talaj-stock.adobe.com

Patient Navigation Is Nonnegotiable in Cancer Care

By Maggie L. Shaw

May 1st 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

Dr Robert Green Explains Challenges, Promise of Big Data in Oncology

December 8th 2015

Dr Robert Green Explains Challenges, Promise of Big Data in Oncology

The challenge with data in oncology is making sense of it and connecting it in a way that clinicians can make insights that inform the care they provide patients in real time, said Robert J. Green, MD, vice president of clinical strategy and senior medical director at Flatiron Health.

December 8th 2015

Novel Combinations in Multiple Myeloma and Lymphoma

Michael R. Page, PharmD, RPh Surabhi Dangi-Garimella, PhD

Results from a subgroup analysis of the phase 3 ENDEAVOR study and a phase 2 study in diffuse large B cell lymphoma patients were presented at the annual meeting of the American Society of Hematology.

December 8th 2015

ASH Leverages Recommendations From Other Medical Organizations, Advising Hematologists to Choose Wisely

Surabhi Dangi-Garimella, PhD

Members from the American Society of Hematology (ASH)'s Choosing Wisely Task Force presented 5 recommendations on Monday, December 7, 2015, at the 57th annual meeting of ASH, in Orlando, Florida.

December 7th 2015

Do Hematologists Believe APMs Afford Fair Value? An Open Discussion at ASH

Surabhi Dangi-Garimella, PhD

On the second day of the annual meeting of the American Society of Hematology, physicians got together to discuss the real-world needs of alternate payment models in hematology.

December 7th 2015

Study Shows Academic Hospitals More Adept at Caring for ALL Patients

Surabhi Dangi-Garimella, PhD

During a health outcomes session on the second day of the American Society of Hematology meeting, data presented from a study conducted at the University of Nebraska Medical Center suggested that the site of care bears a significant influence on the outcomes of patients with acute lymphoblastic leukemia.

December 6th 2015

Importance of Patient-Reported Outcomes and Quality-of-Life Measures in Myeloid Disease

Surabhi Dangi-Garimella, PhD

Two posters presented at the annual meeting of the American Society of Hematology discussed patient-reported outcomes measures and quality-of-life indicators as supportive tools for treatment in individuals being treated for acute myeloid leukemia and myelodysplastic syndrome.

December 6th 2015

How Do You Develop, and Successfully Incorporate, PROs in Hematology? Experts Chime in at ASH

Surabhi Dangi-Garimella, PhD

Presenters at an education session, titled Patient-Reported Outcomes in Hematology, addressed the importance of embracing the patient perspective in healthcare delivery, on the second day of the annual meeting of the American Society of Hematology, being held December 5-8, in Orlando, Florida.

December 5th 2015

Experts Share Concepts of Quality Measures and Pay-for-Performance at the Annual ASH Meeting

Surabhi Dangi-Garimella, PhD

At the annual meeting of the American Society of Hematology, providers brooded over implications of quality measures and how they will influence clinical practice in the coming years.

December 5th 2015

New Hematology Drugs: Progress and Challenges Discussed at the 57th ASH Meeting

Surabhi Dangi-Garimella, PhD

An early session on the first day of the annual meeting and exposition of the American Society of Hematology, being held December 5-8, 2015, in Orlando, Florida, saw presentations on the promise of newly approved hematology/oncology agents, in addition to the challenges that clinicians face in treating patients with these drugs.

December 4th 2015

5 Things to Look for at the Annual Meeting of the American Society of Hematology

Surabhi Dangi-Garimella, PhD

As the annual meeting of the American Society of Hematology kicks off on Saturday, December 5, 2015, a lot of new clinical data will be presented, practice-changing treatments will be introduced, and new healthcare policies will be discussed.

December 3rd 2015

What Is the True Financial Impact of Prescription Medications? Advera Health Explains

Surabhi Dangi-Garimella, PhD

In a study published in the Journal of Managed Care & Specialty Pharmacy, the authors present a rating system that includes downstream costs following treatment to estimate the real-world financial impact of the drug.

December 2nd 2015

Antidepressant Use Safe for Stress in Breast Cancer, Says Kaiser Study

Surabhi Dangi-Garimella, PhD

An exhaustive study published by Kaiser Permanente in the Journal of the National Cancer Institute has confirmed that antidepressants do not cause recurrence in breast cancer patients treated with tamoxifen.

December 2nd 2015

Stress a Significant Determinant of Breast Cancer Outcomes

Surabhi Dangi-Garimella, PhD

A study published in the journal Breast Cancer Research and Treatment cognitive-behavioral stress management introduced early in care management can improve breast cancer outcomes.

December 1st 2015

Consider Race Prior to Neoadjuvant Breast Cancer Chemotherapy, Oncologists Recommend

Surabhi Dangi-Garimella, PhD

A new study suggests that a poor response to neoadjuvant chemotherapy-frequently administered to black, Hispanic, and Asian women-could dictate survival rates in breast cancer.

Ted Okon Outlines the Importance of Payer-Provider Dialogues

November 30th 2015

Ted Okon Outlines the Importance of Payer-Provider Dialogues

The current dialogue occurring between payers and providers is critical in today's healthcare environment, and it's an interaction that certainly was not happening just 5 or 6 years ago, according to Ted Okon, executive director of the Community Oncology Alliance.

November 30th 2015

FDA's Decision on Elotuzumab Further Expands Options in Multiple Myeloma

Surabhi Dangi-Garimella, PhD

Following the approval of daratumumab earlier this month, multiple myeloma patients now have another opportunity to combat the disease: elotuzumab.

November 30th 2015

Pharmaceutical Advertising Increased Prescription Drug Utilization, Study Reports

Surabhi Dangi-Garimella, PhD

Relaxed direct-to-consumer advertising restrictions for drugs by the FDA in 1997 has precipitated an increase in prescription drug utilization, not just among Medicare enrollees, but also among non-elderly users.

Dr Kavita Patel Outlines How Oncology Is Ripe for Delivery Reform

November 27th 2015

Dr Kavita Patel Outlines How Oncology Is Ripe for Delivery Reform

Oncology, like primary care, is ripe for delivery reform, but it has remained stuck in a fee-for-service mindset, said Kavita Patel, MD, fellow in economic studies and managing director at Brookings Institution.

November 27th 2015

American College of Physicians Recommends More Use of Generic Medications

Surabhi Dangi-Garimella, PhD

The American College of Physicians has published a paper in the Annals of Internal Medicine that advices clinicians to prescribe generic drugs whenever possible.

November 25th 2015

At Thanksgiving, Take Time to Collect Family Medical History

Mary K. Caffrey

Waiting until there's a cancer diagnosis or other crisis is not the time to be taking the family's medical history. Testing companies and genetic counselors encourage families to share information when they are all in one place.

Joy Larsen Haidle Discusses How Patients Should Use Genetic Tests

November 24th 2015

Joy Larsen Haidle Discusses How Patients Should Use Genetic Tests

Patients considering using a genetic test should meet with a genetic counselor first to get a better understanding of the patient's goal for getting the test done and determine the likelihood that a test might be useful, explained Joy Larsen Haidle, MS, CGC, president of the National Society of Genetic Counselors.

November 24th 2015

Another First for Nivolumab: Approved as Frontline for BRaf Wild Type Melanoma

Surabhi Dangi-Garimella, PhD

The approval follows 5 months after Bristol-Myers Squibb submitted phase 3 results of the Checkmate-066 trial for FDA review.

November 23rd 2015

Nivolumab Approved for Third Indication: Advanced Renal Cell Carcinoma

Surabhi Dangi-Garimella, PhD

Two months after being granted a Breakthrough Therapy designation by the FDA for metastatic renal cell carcinoma (mRCC), nivolumab was today approved by regulators for treating mRCC patients who have failed a certain type of prior therapy.

November 23rd 2015

Decade-Long Screening Efforts Bear Fruit for CRC Screening in New York City

Surabhi Dangi-Garimella, PhD

A state-led program, initiated in 2003, has nearly doubled screening colonoscopy rates in New York City and also eliminated racial and ethnic disparities in the process.

November 22nd 2015

Staying Focused on the Cancer Patient, Amid Rising Drug Costs and New Payment Models

Giving cancer patients what they want and need is the goal, but getting there isn't easy, according to healthcare experts who took part in Patient-Centered Oncology Care 2015, presented November 19-20, 2015, by The American Journal of Managed Care. Drug costs demand difficult conversations about value, and changes in the law require oncologists to learn whole new ways to be paid.

November 21st 2015

As Prospect of Risk for Doctors Looms, Cost Conversation Shifts in Cancer Care

Mary K. Caffrey

Three years after Memorial Sloan Kettering Cancer Center refused to add Zaltrap to its formulary due to cost, value is part of the national conversation in cancer care. The new question is what will happen when physicians assume risk.

Dr Scott Gottlieb Worries About More FDA Regulation in Diagnostic Testing

November 21st 2015

Dr Scott Gottlieb Worries About More FDA Regulation in Diagnostic Testing

If the FDA steps in to regulate laboratory-developed tests, it will slow down innovation, add costs to the development of the product, and likely decrease the number of tests that come out, but the public health benefits of increased oversight might be worth it, said Scott Gottlieb, MD, resident fellow at the American Enterprise Institute.

Dr Peter Bach Examines the Problems of the 340B Drug Pricing Program

November 21st 2015

Dr Peter Bach Examines the Problems of the 340B Drug Pricing Program

While the 340B Drug Pricing Program was designed to help facilities that take care of impoverished patients with low-cost drugs, what the program has morphed into is almost the opposite of what it was intended to do, said Peter Bach, MD, MPP, director of Memorial Sloan Kettering's Center for Health Policy and Outcomes.

November 21st 2015

Are PBMs the Answer to Managing the High Cost in Oncology Care?

Surabhi Dangi-Garimella, PhD

A pharmacist who engages in formulary decisions, a medical director for population management for a private health exchange, and an innovations leader at a pharmacy benefit manager, took to the podium at the Patient-Centered Oncology Care meeting on November 20, 2015, to discuss cost-saving strategies in oncology and whether benefit managers can play a role in reining-in some of these costs.

November 20th 2015

End-of-Life and Palliative Care to Be Discussed During AJMC's November 24 Tweetchat

During a tweetchat on November 24 at 3:30 pm EST, Amy Berman, RN, BS, and Judith R. Peres, LCSW-C, will discuss patient-centered care, palliative care, and end-of-life care.

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