Oncology

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Tarlatamab Safety Varies Between Clinical and Real-World SCLC Trials

By Hayden E. Klein

May 6th 2025

The bispecific T-cell engager tarlatamab demonstrated favorable antitumor activity in a small cohort with small cell lung cancer (SCLC), but it was also linked to higher rates of serious adverse events like cytokine release syndrome than seen in clinical trials.

CureCancer | Image Credit: © MMPhoto21-sotck.adobe.com

COA 2025: Insight, Innovation, and Independent Strength

By Maggie L. Shaw

May 5th 2025

Community Oncology Reacts to Trump's Drug Pricing Executive Order

By Maggie L. Shaw

May 2nd 2025

Melanoma & Skin Cancer Awareness Month | Image credit: Waseem Ali Khan - stock.adobe.com

5 Things You Should Know About Skin Cancer

By Pearl Steinzor

May 2nd 2025

stethoscopewithcompass | Image Credit: © Talaj-stock.adobe.com

Patient Navigation Is Nonnegotiable in Cancer Care

By Maggie L. Shaw

May 1st 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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Dr Bruce Quinn Describes How Europe and the US Regulate Diagnostic Tests Differently

November 20th 2015

Dr Bruce Quinn Describes How Europe and the US Regulate Diagnostic Tests Differently

While the FDA could regulate diagnostic tests the way they are in Europe-through simple verification that the test is accurate-the FDA has not chosen to do that and comes closer to requiring clinical utility, explained Bruce Quinn, MD, PhD, senior director at FaegreBD Consulting.

Dr Julie Vose Weighs in on Value Calculators, MACRA

November 20th 2015

Dr Julie Vose Weighs in on Value Calculators, MACRA

Julie M. Vose, MD, MBA, FASCO, president of the American Society of Clinical Oncology (ASCO), and keynote speaker at this year's Patient-Centered Oncology Care meeting, discusses addressing cost of care, using value calculators, and the Medicare Access and CHIP Reauthorization Act.

November 20th 2015

What We're Reading: CMS Wants to Penalize Doctors for Prostate Tests

What we're reading, November 20, 2015: CMS wants to penalize doctors for ordering routine prostate-cancer screening tests; lawmakers, patients, and advocates call for head of Drug Enforcement Agency to be fired; and specialty drug costs exceed household incomes.

November 20th 2015

FDA Seems Poised to Regulate LDTs in Oncology, but Is That a Good Thing?

Mary K. Caffrey

A panel that discussed the prospect of FDA regulation of diagnostic tests in oncology helped open Patient-Centered Oncology Care November 19, 2015, in Baltimore, Maryland.

November 20th 2015

ASCO President Reviews Post-SGR Challenges for Oncologists

Surabhi Dangi-Garimella, PhD

At the Patient-Centered Oncology Care 2015 meeting, held November 19-20, 2015, in Baltimore, Maryland, keynote speaker Julie M. Vose, MD, MBA, FASCO, president of the American Society of Clinical Oncology provided perspectives on the challenges faced by oncologists as the healthcare system transitions to define and incorporate value in the care delivered.

November 19th 2015

Addressing the Elephants in the Room: Healing Through Discussion

Samantha Eisenstein Watson, MBA

Collaboration between organizations serving the young adult cancer population benefits all involved

November 19th 2015

Absence of Prescription Coverage Could Prove Catastrophic in Cancer, Study Shows

Surabhi Dangi-Garimella, PhD

Eligibility for prescription coverage and family income significantly influenced women's decisions to continue hormonal therapy and prevent recurrence of breast cancer, the authors found.

November 18th 2015

ASCO Responds to CMS on Reimbursement Changes Under MACRA

Surabhi Dangi-Garimella, PhD

The American Society of Clinical Oncology has made public its detailed guidance to CMS, supporting implementation of physician-focused and other alternative payment models under MACRA.

Joy Larsen Haidle on How the Genetic Testing Landscape Has Changed

November 18th 2015

Joy Larsen Haidle on How the Genetic Testing Landscape Has Changed

After the Supreme Court struck down gene patents, not only is more genetic testing is being offered, but the technology of the test has expanded to the benefit of patients, said Joy Larsen Haidle, MS, CGC, president of the National Society of Genetic Counselors.

November 18th 2015

Sandoz Biosimilar to Amgen's Neulasta Filed for Regulatory Approval

Surabhi Dangi-Garimella, PhD

This is the company's third biosimilar Biologics License Application in the United States.

November 17th 2015

Tagrisso Approved, but Can Patients With EGFR-Mutant NSCLC Afford It?

Surabhi Dangi-Garimella, PhD

The drug is estimated to cost close to $13,000 per month.

November 17th 2015

FDA Regulation of LDTs: A Report Justifies the Need for It

Surabhi Dangi-Garimella, PhD

It is time to regulate laboratory-developed tests that cost Medicare $9.7 billion in the year 2012 alone.

November 16th 2015

Daratumumab Approval Yields the First Monoclonal Antibody, and Another Option, in Multiple Myeloma

Surabhi Dangi-Garimella, PhD

The drug was approved based on results of 2 open-label studies that showed reduction in tumor burden of patients who had previously received multiple lines of therapy.

November 16th 2015

Should We Trust Screening Age Recommendations in Cancer?

Surabhi Dangi-Garimella, PhD

When to screen and how to screen remain controversial issues in prostate cancer.

This Week in Managed Care: November 14, 2015

November 14th 2015

This Week in Managed Care: November 14, 2015

This week in managed care the top stories include pivotal results from the SPRINT study on blood pressure, an analysis on how states successfully enrolled consumers in the insurance marketplace, and experts discuss value-based care.

November 13th 2015

Creating a Supportive Environment Through the Use of Palliative Care

Laura Joszt, MA

Panelist discuss early referral to palliative care, enduring misconceptions, culture considerations, and more at the Fall Managed Care Forum 2015.

November 12th 2015

Smoking Rates Declining but Disparities Evident: CDC Report

Surabhi Dangi-Garimella, PhD

According to the CDC, while smoking rates are seeing a steady decline, rates for uninsured and adults on Medicaid are more than twice those for adults with private health insurance.

November 12th 2015

Learning From Your Daughters About Cancer Prevention

Surabhi Dangi-Garimella, PhD

A study in The European Journal of Public Health finds conversation on preventive vaccination against HPV can motivate participation in preventive screening for cervical cancer.

November 11th 2015

Oral Contraceptives Can Improve Outcomes in Ovarian Cancer

Surabhi Dangi-Garimella, PhD

A retrospective study conducted at the Mayo Clinic found improved OS and PFS in ovarian cancer patients with a history of oral contraceptive use.

November 11th 2015

Narrow Network and Insolvent Exchange Plan Leaves Cancer Patients Scampering for Options

Surabhi Dangi-Garimella, PhD

A forced closing of Health Republic Insurance of New York has left many in need of immediate coverage.

Dr Crystal S. Denlinger Discusses Potential Cardiotoxicity Concerns for Cancer Survivors

November 10th 2015

Dr Crystal S. Denlinger Discusses Potential Cardiotoxicity Concerns for Cancer Survivors

Historically cancer survivorship programs have not emphasized cardiac follow-up and there is not a lot of long-term data on cardiac toxicity in patients who received certain drugs, but that is changing as patients live longer and fuller lives after treatment, explained Crystal S. Denlinger, MD, from the Fox Chase Cancer Center in Philadelphia.

November 10th 2015

Cobimetinib/Vemurafenib Receives FDA Approval in Advanced Melanoma

The approval comes after a priority review of the combination that blocks activity of 2 MAPK proteins: BRAF and MEK.

November 10th 2015

A Cancer Prevention Trial Identifies Predictive Biomarker in Oral Cancer Development

Surabhi Dangi-Garimella, PhD

Published in JAMA Oncology, the trial found an association between loss of heterozygosity and cancer-free survival in patients who had been diagnosed with oral premalignant lesions.

November 9th 2015

Medi-Cal Cancer Patients Perform Worse Than Those on Other Insurance, UC Davis Study

Surabhi Dangi-Garimella, PhD

Heterogeneity in quality of care and cancer patient survival based on insurance coverage are the highlight of a report by researchers at the Institute for Population Health Improvement at the University of California Davis.

November 9th 2015

Exceptional Response in Brain Tumor Patient Instills Confidence in Personalized Medicine

Surabhi Dangi-Garimella, PhD

Treatment of a recurrent brain tumor harboring a BRAF mutation with an inhibitor approved for melanoma resulted in dramatic tumor shrinkage.

November 8th 2015

Advancing the Wave of Democratization of Cancer Care

Emmanuel F. Petricoin III, PhD

Democratizing the complex field of cancer care is not easy. We are providing patients with key information that their own cancer is unique and needs to be treated as such, but there is a great deal of work to be done in putting that knowledge to work.

This Week in Managed Care: November 7, 2015

November 7th 2015

This Week in Managed Care: November 7, 2015

This week in managed care Kentucky elected a new governor who could bring big changes to the state's Medicaid program, researchers reported that costs of dementia in the last 5 years of life surpass even cancer, and the latest Hospital Safety Score report was released.

November 6th 2015

Plavix Does Not Increase the Risk of Cancer

Surabhi Dangi-Garimella, PhD

The FDA's meta-analyses, following results of the DAPT trial in 2014, have found no association between treatment with the blood thinner clopidogrel (Plavix) and increased incidence of, or death due to, cancer.

November 6th 2015

5 Things to Know About Value in Healthcare

Surabhi Dangi-Garimella, PhD

From CMS to private health plans, professional healthcare organizations to patients and advocacy groups, the discussion nowadays seems to end up with value.

Linda House on Considering How a Patient's Needs May Change

November 5th 2015

Linda House on Considering How a Patient's Needs May Change

As patients with cancer live longer and the disease becomes a chronic disease for many, it becomes important for providers to understand how the needs of the patient change from being newly diagnosed to active therapy to long-term therapy, explained Linda House, president of the Cancer Support Community.

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