Oncology

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The findings suggest that inhibition of midkine might be a meaningful tool to improve treatment outcomes in SCLC. | Image credit: Pixel-Shot - stock.adobe.com

July 24th 2025

New data show midkine expression is heightened in small cell lung cancer, suggesting the growth factor may be an important therapeutic target.

The FDA has issued a complete response letter for RP1 plus nivolumab for advanced melanoma after a PD-1 inhibitor–containing regimen. | Image credit: ra2studio - stock.adobe.com

RP1 Plus Nivolumab Receives CRL for Advanced Melanoma

By Chris Ryan

July 24th 2025

David Nguyen, MD | Image Credit: Tufts Medicine

It Take a Village in Cancer Care: A Q&A With David Nguyen, MD

By Maggie L. Shaw
David Nguyen, MD

July 23rd 2025

In Data Race, Flatiron Health Touts Tripling of Global Oncology Research Network

By Mary Caffrey

July 23rd 2025

Emerging therapies, including immune checkpoint inhibitors and antibody-drug conjugates, could significantly impact SCLC treatment, authors of a recent review concluded. | Image credit: Vitalii Vodolazskyi - stock.adobe.com

Is a New Era of SCLC, LCNEC Treatments on the Horizon?

By AJMC Contributor

July 23rd 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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July 25th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology

July 25th 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

More News

January 12th 2016

Kentucky's Bevin Tells Feds He's Dismantling Exchange

Mary Caffrey

Rates of uninsured dropped faster than almost anywhere in the nation, but Kynect is part of "Obamacare," and the new Republican Governor Matt Bevin has vowed that it must go. Advocates have a lot of questions about how hard-to-target populations will be reached and whether grant funds will have to be repaid.

January 12th 2016

PBMs Can Help Bend the Cost Curve: Express Scripts' Tim Wentworth

Surabhi Dangi-Garimella, PhD

At the J P Morgan Healthcare Conference, Express Scripts' president Tim Wentworth shared the solutions being developed by the pharmacy benefit manager to improve patient access while reducing cost to payers.

January 11th 2016

Illumina Attempts Cancer's Holy Grail: A Pan-Cancer Liquid Biopsy Test

Surabhi Dangi-Garimella, PhD

Grail, which has raised over $100 million from Illumina and the venture capital firm Arch Venture Partners, has also secured investments from Bill Gates, and Jeffrey P. Bezos.

January 11th 2016

Dr Crystal S. Denlinger on Cardio-Oncology Follow-Up

New guidelines from the National Comprehensive Cancer Network regarding cardiac toxicity for patients with cancer or cancer survivors should have cancer institutions talking about how to implement cardiac follow-up for patients, said Crystal S. Denlinger, of FOx Chase Cancer Center.

January 11th 2016

Vice President's Focus on Moonshot Initiative During Last Year in Office

Surabhi Dangi-Garimella, PhD

Following a personal tragedy, vice president Joe Biden has sworn to dedicate his last year in office to help boost cancer research.

January 11th 2016

What We're Reading: Drug Shortages Rise Sharply in EDs

AJMC Staff

What we're reading, January 11, 2016: drug shortages in the emergency departments have quadrupled since 2008; the government has done little to verify people enrolling after Obamacare deadline under special enrollment categories; and Pfizer increased the prices of 100 drugs.

January 10th 2016

Top Healthcare News: New Dietary Guidelines and Cancer Treatment Advances

The latest developments across the healthcare landscape and key upcoming conferences to attend.

January 10th 2016

Dr Charles Bane on the Impact of Rising Expenditures on Practices

The increase in medical expenditures and the move to new care models in oncology will necessitate a change in culture for practice staff, said Charles Bane, MD, Dayton Physicians Network in Ohio.

January 9th 2016

Trial Tests Safety of Promising Therapy for Patients With Type 1 Diabetes

Jessica Men

A recent safety trial has found a promising new therapy for type 1 diabetes that uses patients’ own regulatory T-cells instead of the usual immunosuppressive drugs to protect beta cells.

January 9th 2016

This Week in Managed Care: January 9, 2016

Top managed care stories include Sanofi ending its deal to market Afrezza, Aetna cut ties with America's Health Insurance Plans, and a new study found bankruptcy looms large for cancer survivors.

January 8th 2016

Are We Finally Ready to Rethink Prescription Drug Pricing?

Leigh Purvis, MPA

It's time to finally put an end to “what the market will bear” as a method of pricing prescription drugs.

January 8th 2016

Study Raises Questions on Benefits of Organ Transplant

Surabhi Dangi-Garimella, PhD

Solid-organ transplants increase the risk of death due to cancer compared with the general population, a study published in JAMA Oncology has found.

January 8th 2016

5 Things to Know About the 2015 Dietary Guidelines

Mary Caffrey

The guidelines show the influence of lobbyists, raising questions about how they will be created in future cycles. They will next be updated in 2020.

January 7th 2016

4D CT Could Spare Normal Lung Function in Lung Cancer Patients

Surabhi Dangi-Garimella, PhD

A study by researchers at the University of Colorado Cancer Center is evaluating an imaging method that can help protect normal, healthy lung tissue during radiotherapy treatment in lung cancer patients.

January 7th 2016

Adequate Screening, Prevention, and Treatment Saved 1.7 Million Lives: ACS Report

Surabhi Dangi-Garimella, PhD

A 23% drop in cancer deaths in the United States between 1991 and 2012-which translates into 1.7 million lives saved-was the result of successful cancer prevention, screening, and treatments, says a new report published by the American Cancer Society.

January 6th 2016

Cardiovascular Screening Can Identify Toxic Effects in Adult Cancer Survivors

Surabhi Dangi-Garimella, PhD

A study published in the Annals of Internal Medicine underscores the need for early cardiovascular screening in adult survivors of cancer.

January 6th 2016

After Surviving Cancer, Bankruptcy Looms Large in Working-Age Individuals, Says Kaiser Study

Surabhi Dangi-Garimella, PhD

A new study conducted by researchers at Kaiser Permanente has found that a considerable number of working-age adults who survive cancer and its toxic treatments, end up with substantial medical debts or declare bankruptcy.

January 6th 2016

Combating Patients' Resistance to Targeted Cancer Drugs

Jackie Syrop

Drugs targeting genetic mutations that drive tumor growth have revolutionized treatment for some serious forms of cancer, but the tumors usually become resistant to the drugs’ therapeutic effects and resume growth.

January 5th 2016

7 in 10 Teens Exposed to E-Cigarette Ads, CDC Finds

Mary Caffrey

Public health officials are worried about the increased popularity of e-cigarettes because they could be a gateway to the use of combustible tobacco products.

January 5th 2016

Lack of Paid Sick Leave Places Huge Financial Burden on Patients With Cancer

Jackie Syrop

Patients with cancer who have paid sick leave are almost twice as likely to retain their jobs.

January 5th 2016

With Hands Tied, CMS' NTAP for Blinatumomab Is Ridden With Controversy

Surabhi Dangi-Garimella, PhD

In their Viewpoint in JAMA Oncology, Sanket S. Dhruva, MD, and Vinay Prasad, MD, MPH, have raised objections to CMS’ turnaround on coverage decision for the antibody blinatumomab.

January 4th 2016

Improving Access to Breast Cancer Screening in the Absence of a Mammogram

Surabhi Dangi-Garimella, PhD

Results from the ACRIN 6666 trial have found that breast cancer detection rate using ultrasonography is comparable with mammography.

January 4th 2016

Improving Precision and Outcomes of Cancer Surgery

Surabhi Dangi-Garimella, PhD

An imaging agent that can eliminate the unknown and help instill confidence in a surgeon’s ability to successfully remove all cancerous tissue is being evaluated by surgical oncologists at Duke University.

January 3rd 2016

Age Affects Breast Cancer Patients' Reaction to 2 Drugs

Jackie Syrop

How well postmenopausal patients tolerate tamoxifen and anastrozole for one type of breast cancer varies with age.

January 2nd 2016

Older Women with Breast Cancer Survive Better with Treatment Therapy

Priyam Vora

Women over 65 years of age with early-stage, fast-spreading breast cancer had better chances of surviving if they endured treatment therapy, according to a new study.

January 1st 2016

5 Things to Know About Biosimilars in the New Year

Surabhi Dangi-Garimella, PhD

An update on where the field of biosimilars currently stands.

December 31st 2015

Can Virtual Colonoscopies Be a Reality for Population Screening?

Surabhi Dangi-Garimella, PhD

A study published in the Journal of the National Cancer Institute found that ease of preparation prior to the screening test is an important determinant of colonoscopy uptake.

December 31st 2015

Aspirin May Lower Breast Tissue Density, Lead to Early Detection of Cancer

Jackie Syrop

New data does not support the idea that aspirin has protective qualities and “down-the-road” benefits for breast cancer patients. It may, however, help reduce breast density and improve earlier detection of some breast cancers.

December 30th 2015

Closing Statements

December 30th 2015

Are Patients Aware of Site of Care Differentials?

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