Oncology

Latest News

Dordaviprone is indicated for recurrent H3 K27M-mutant diffuse midline glioma, an ultra-rare, aggressive brain tumor primarily affecting children. | Image credit: wladimir1804 - stock.adobe.com

FDA Approves Dordaviprone as First and Only Treatment for Aggressive Form of Glioma

By Rose McNulty

August 6th 2025

Dordaviprone (Modeyso) is now approved to treat recurrent H3 K27M-mutant diffuse midline glioma, an ultra-rare, aggressive brain tumor primarily affecting children.

Gen Li, PhD, MBA, president and founder of Phesi

Real-World Data, Digital Patient Profiles Are Revolutionizing Trial Design, Patient Recruitment: Gen Li, PhD, MBA

By Pearl Steinzor
Gen Li, PhD, MBA

August 4th 2025

Value-based care. | Image Credit: irissca - stock.adobe.com

Legal Navigation Services Key to Addressing Disparities in Cancer Care

By Cameron Santoro

July 31st 2025

Radiotherapy can work synergistically with immunotherapy by reprogramming the tumor microenvironment. | Image credit: Crystallight-stock.adobe.com

Brain Radiotherapy Plus ICIs Boost Survival in SCLC With Brain Metastases

By Jared Kaltwasser

July 30th 2025

As SCLC continues to pose a therapeutic challenge due to rapid progression and early metastasis, the convergence of immunotherapy and precision radiation holds promise to extend survival and improve outcomes. | Image credit: mi_viri - stock.adobe.com

Chemoimmunotherapy Shows Promise for Limited-Stage SCLC in Real-World Study

By AJMC Contributor

July 29th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

Continuing Medical Education

August 13th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology

August 13th 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

More News

February 24th 2015

Study Warns Against Use of VEGF Inhibitors in Advanced Kidney Cancer

Interim analysis of a clinical trial evaluating adjuvant sorafenib, sunitinib or placebo in patients with advanced renal cell carcinoma found the recurrence rates and the disease-free survival were similar between all three treatment regimens.

February 23rd 2015

First HDAC Inhibitor, Developed by Novartis, Approved for Multiple Myeloma

Study results showed participants receiving Farydak with bortezomib and dexamethasone saw a progression-free survival for about 10.6 months,compared to 5.8 months in participants treated with bortezomib and dexamethasone alone.

February 23rd 2015

Coalition of Leading Cancer Centers Aims to Improve Personalized Treatment

"The growth of ORIEN coincides with President Obama's announcement and the recognition that molecularly targeted medicine holds tremendous promise for all disease, particularly cancer," said Michael Caligiuri, MD, director of The Ohio State University Comprehensive Cancer Center and CEO of the James Cancer Hospital and Solove Research Institute.

February 23rd 2015

BMS Deals Set to Boost Company's Oncology Pipeline

The deals, with Flexus and Rigel, will add another molecule to the company's immunotherapy pipeline and also provide access to a TGF-beta receptor inhibitor to be used in combination with Yervoy and Opdivo.

February 23rd 2015

Taiho's NDA for mCRC Under FDA Review

The TAS-102 RECOURSE trial met the primary efficacy endpoint of statistically significant improvement in overall survival versus placebo, and the results of the trial form the basis of the NDA.

February 23rd 2015

Expert Analysis on Managing mCRC

At the 26th International Congress on Anti-Cancer Treatment in Paris, France, earlier this month, oncologists deliberated on the current understanding of metastatic colorectal cancer and the available treatment options. Recent work has shown that there are 4 or 5 different subtypes of the disease, which may call for personalized therapeutic strategies.

February 21st 2015

Managed Care Minute: February 21, 2015

A one-minute look at managed care news during the week of February 16, 2015, including extended open enrollment under the Affordable Care Act and shared decision-making for cancer treatments.

February 20th 2015

Celgene's Revlimid Receives Expanded Approval in Europe Following Similar FDA Approval

After the FDA approved lenalidomide for use in chemotherapy-naive multiple myeloma (MM) patients, the European Commission has followed suit. Revlimid was approved today by EC in MM patients, previously untreated and transplant-ineligible.

February 20th 2015

Study Underscores the Potential of Mobile Health App in Healthcare Decisions

The study, conducted at the Columbia University School of Nursing, found that mobile apps with decision support features resulted in significantly higher diagnosis rates than apps with only bare-bones tools for recording results from a patient exam.

February 20th 2015

UCLA Study Points to Need for Informed Decision-Making in Prostate Cancer

The study evaluated SEER data of over 37,000 prostate cancer patients and found an overwhelming majority of patients (58%) received radiation treatment regardless of overall disease prognosis. The lead study author hopes these findings enlighten the public and allow physicians to make an informed decision when it comes to the best treatment option for men who may or may not benefit from radiation therapy in the long run.

February 20th 2015

FDA Authorizes Sale of First Direct-to-Consumer Genetic Test

Developed by the company 23andMe, the test identifies carriers of a gene mutation that could determine the susceptibility of a person's offspring to Bloom Syndrome.

February 19th 2015

Study Results Challenge CMS Position on Follow-Up Scans in Cancer Patients

Published in the Journal of Nuclear Medicine, the authors show that a fourth and subsequent follow-up PET/CT scan in lung cancer patients was associated with treatment change.

February 19th 2015

Biomarker That Could Predict Survival After CRC Surgery Discovered

Research scientists at the Macquarie University and Concord Repatriation General Hospital in Australia have discovered that expression of the cell surface protein uPAR can predict survival after colorectal cancer (CRC) surgery. The study found that patients expressing uPAR may have undetectable cancer metastasis and dramatically poorer survival.

February 19th 2015

Gardasil 9 Offers Broader Protection, a Global Study Reports

Published in the New England Journal of Medicine, the multinational study found that Gardasil 9, 100% effective against 9 strains of HPV, can prevent the occurrence of 85%-90% of HPV-related cancers.

February 18th 2015

Phyllis Torda Championed Improved Quality Measurement Guidelines in Oncology

On February 16, after living with metastatic breast cancer, Phyllis Torda, 63, vice president of the Quality Solutions Group at the National Committee for Quality Assurance, passed away.

February 18th 2015

Balancing Value, Pathways, and Innovation in Healthcare

As specialty drug costs, formulary wars, and reimbursement models grab headlines everyday, we need to take a step back and visualize how all of this might impact innovation and whether the patient stands to lose in the process.

February 18th 2015

FDA Expands Indication for Revlimid in Multiple Myeloma

Laura Joszt, MA

The combination of Revlimid with dexamethasone, previously approved for treatment in patients with multiple myeloma who received at least 1 prior treatment, has received FDA approval for use in newly diagnosed multiple myeloma patients.

February 18th 2015

Study Identifies Potential Biomarker for Cabazitaxel Response in CRPC

The study published in Clinical Cancer Research elucidated an in vitro mechanism that could explain why cabazitaxel is more effective in some prostate cancer patients. The study also identified a biomarker that could provide precision medicine for a subset of patients.

February 17th 2015

Oncologist to Launch Social Media Campaign Against Cost of Cancer Drugs

Following his collaboration with other research scientists to protest the cost of cancer drugs, Hagop Kantarjian, MD, from the MD Anderson Cancer Center has now turned to patients.

February 17th 2015

Doctors Need to Be Tech Savvy, Report Suggests

The survey, conducted by salesforce.com, showed that 71% patients want their doctor to use a mobile application to schedule appointments, share health data, and manage preventive care; 60% patients reported an interest in using telehealth in place of in-person visits.

February 17th 2015

Cancer Patients Associated Shared-Decision Making With Quality Care

Laura Joszt, MA

Cancer patients with less involvement in their treatment decisions are less likely to report excellent quality of care even if they prefer physician-controlled decisions, according to a study in JAMA Oncology.

February 17th 2015

Study Urges Lung Cancer Trials to Include Survivors

The study, published in the Journal of the National Cancer Institute, found that having a prior cancer diagnosis did not affect outcomes among the patients with advanced lung cancer, which means these patients should be allowed to take part in clinical trials of new lung cancer treatments.

February 16th 2015

Improving the Value of Immune-Based Therapies

Richard W. Joseph, MD

February 16th 2015

Issues Impacting Stakeholder Adoption of Immuno-Oncology

Bruce Feinberg, DO

February 16th 2015

New Standards of Care in the Management of Prostate Cancer

Surabhi Dangi-Garimella, PhD

February 16th 2015

Payers Evaluate the Clinical Utility of Diagnostic Tests

Surabhi Dangi-Garimella, PhD

February 16th 2015

Innovation and the Role of Alternative Markers of Efficacy

Sejal Saraiya, PharmD

February 16th 2015

The Use and Implementation of Standardized Treatment Pathways

Sejal Saraiya, PharmD

February 16th 2015

Arguments Taking Shape For and Against FDA Regulation of Diagnostic Tests

Mary K. Caffrey

February 16th 2015

HHS Announces New Oncology Care Management Initiative

Laura Joszt, MA

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