Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com

C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

By Jared Kaltwasser

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com

Novel Biomarkers May Inform Prognosis in SCLC

By AJMC Contributor

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

By Rose McNulty

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center

ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

By Mary Caffrey

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com

5 Key FDA Approval Dates Mark a Milestone-Filled May

By Brooke McCormick

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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January 24th 2015

Managed Care Minute: January 24, 2015

A one-minute look back at the week of January 19, 2015, in managed care, including Marilyn Tavenner's departure from CMS and oncology drug pricing.

January 23rd 2015

Bayer Wants Patient Engagement in Early Drug Development

Bayer is collaborating with MD Anderson in Texas to develop a questionnaire that will query a patient's disease-related symptoms, a step to include PROs in early drug development which could help reduce adverse effects in the final product.

January 23rd 2015

Panel Discussion: Payer, Provider, and Patient Roles for Understanding the End-of-Life Care Equation: Cost vs Survival Time vs Quality of Life

Amy Berman, BS, RN, Bruce Feinberg, DO, and Patti Forest, MD, MBA, sit on the first panel discussion at Patient-Centered Oncology Care 2015 and discuss advanced directives and end-of-life care.

January 23rd 2015

Segment 7 - Final Thoughts About Which Patients, Which Drugs, and Which Treatment Timeline

January 23rd 2015

Segment 6 - Patient-Reported Outcomes and Other Important Measures

January 23rd 2015

Segment 5 - Surrogate End Points in Clinical Trials: The Right Information?

January 23rd 2015

Segment 4 - Healthcare Policy: Its Impact on Innovation and Financial Waste

January 23rd 2015

Segment 3 - Justifying Costs: A Request for More Evidence

January 23rd 2015

Segment 2 - Comparative Effectiveness Research and Innovation: Do They Clash?

January 23rd 2015

Segment 1 - The Value of Innovation in Oncology Care

January 23rd 2015

Making the Grade on Survivorship: How are Payers Performing?

As cancer care becomes more powerful and people survivor longer, cancer is becoming a chronic disease that patients need to learn how to live with and remain productive. Although the role of payers in survivorship isn't fully baked yet, there is more focus in the area, according to Ira Klein, MD, MBA, FACP, chief medical officer at Aetna.

January 23rd 2015

When Is the Right Time for Palliative Care?

The Patient-Centered Oncology Care 2014 meeting started off with a talk by Marian Grant, DNP, RN, CRNP, of the University of Maryland School of Nursing, on the topic of palliative care. Although palliative care is appropriate for patients of all ages and in any stage of a serious illness and can be provided alongside curative or disease-modifying treatments, she says she often gets called in very late to offer palliative care to patients.

January 23rd 2015

Early Detection, Cutting Edge Treatments for Breast Cancer Patients

In 2 interviews with Physicians' Education Resource, LLC, award-winning journalist Joan Lunden and Patrick I. Borgen, MD, of Maimonides Medical Center in Brooklyn, NY, discuss breast cancer in advance of the 32nd Annual Miami Breast Cancer Conference.

January 23rd 2015

Vitiligo Could Be a Marker of Efficacy for Melanoma Drugs, Study Indicates

The retrospective analysis conducted in stage 3 and 4 immunotherapy-treated melanoma patients found that the development of vitiligo could serve as a clinical marker for effective antimelanoma immunity and improved clinical outcome.

January 23rd 2015

After Hep C, Express Scripts Aims to Influence Oncology Drug Costs

CMO Steven Miller has already started working with oncologists as the company plans the process of steering physicians to use preferred drugs.

January 22nd 2015

Telehealth Intervention Improved QoL Among Head and Neck Cancer Patients

A telehealth intervention experiment in head and neck cancer patients was found to relive some posttreatment distress symptoms.

January 22nd 2015

The Value of Ultrasound in Breast Cancer Detection

A study conducted in Connecticut showed that ultrasound identified an additional 3.2 women in a 1000 with breast cancer, following a negative mammogram. This has raised a debate on the utility of a screening ultrasound.

January 22nd 2015

Progesterone-Based Contraceptives May Increase the Risk of Gliomas: Danish Study

The study found an increased risk of cancer, contradicting some earlier evidence that suggests the opposite.

January 21st 2015

State of the Union Calls for More Investments in Personalized Medicine

Laura Joszt, MA

In Tuesday night's State of the Union address, President Barack Obama did not spend a lot of time discussing healthcare, but he did highlight medical research and a growing field of medicine by announcing his new Precision Medicine Initiative.

January 21st 2015

ASCO Announces Partner for Groundbreaking CancerLinQ Platform

Mary K. Caffrey

A major technical partner is announced for the long-awaited HIT initiative that will give oncologists a data-derived "second opinion" right from their desktops, with the earliest versions scheduled to come online this year.

January 21st 2015

Patient Navigation Programs a Tremendous Boost for Patient-Centered Care in Oncology

Karyl Blaseg, RN, MS, OCN, writes about the important role of patient navigators in preventing healthcare disparities and promoting patient-centered care among cancer patients.

January 21st 2015

Rigid Cancer Cells Prevent Metastasis, Study Finds

Existing cancer therapies are geared toward massacring tumor cells, but researchers propose a different strategy: subtly hardening cancer cells to prevent them from invading new areas of the body. They devised a way of screening compounds for the desired effect and have identified a compound that shows promise in fighting pancreatic cancer.

January 20th 2015

Amy Berman, RN, Discusses the Importance of Patient-Centered Care in Oncology

For people who have cancer, patient-centered care is particularly important because their life is changing, said Amy Berman, RN, BS, senior program officer at the John A. Hartford Foundation, who also has stage 4 breast cancer.

January 20th 2015

ASCO Declares CLL Regimens Cancer

In it's report, "Clinical Cancer Advances 2015: ASCO's Annual Report on Progress Against Cancer," published in the Journal of Clinical Oncology, 4 newly approved treatments for CLL were predicted to have a dramatic impact on patients with the disease.

January 20th 2015

Potential New Cancer Biomarkers Discovered

The study conducted at the Michigan Center for Translational Pathology studied IncRNAs and their role in cancer.

January 20th 2015

Bigger Regulatory Challenges in Diagnostics Than in Therapeutics, Industry Expert Says

Mary K. Caffrey

January 20th 2015

Best of ASH Presentations: Platelets, Lenalidomide for MDS, and Sorafenib in AML

Surabhi Dangi-Garimella, PhD

January 20th 2015

Improved Cancer Care Through Innovation

Surabhi Dangi-Garimella, PhD

January 20th 2015

Payers Look to CER for Improved Healthcare Decisions

Surabhi Dangi-Garimella, PhD

January 20th 2015

Data Show High Response Rate to Ibrutinib Combination for Patients With Hard-to-Treat MCL

Mary K. Caffrey

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