Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com

C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

By Jared Kaltwasser

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com

Novel Biomarkers May Inform Prognosis in SCLC

By AJMC Contributor

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

By Rose McNulty

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center

ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

By Mary Caffrey

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com

5 Key FDA Approval Dates Mark a Milestone-Filled May

By Brooke McCormick

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

January 20th 2015

Hepatitis C Pricing Wars a Poster Child for Oncology

The CEO of Kite Pharma plans to initiate early conversations with insurers, even before the launch of a clinical trial of their experimental drug, to ensure smooth sailing once the product is approved and launched.

January 19th 2015

Identifying Biomarkers to Detect Lung Cancer in Patient Spit

Researchers at the University of Maryland are evaluating the value of a person's spit to screen for lung cancer, replacing the traditional and recently recommended CT scan.

January 19th 2015

MET Amplification a Viable Screen for NSCLC, Study Claims

A study published in Clinical Cancer Research found that 33% of lung cancer biopsies evaluated had a gain of function amplification in the MET receptor tyrosine kinase.

January 19th 2015

Results Project Savings for Payers With Novel Oral Anticoagulants

Mary K. Caffrey

January 19th 2015

SPIRIT 2: Dasatinib Superior to Imatinib in Newly Diagnosed CML

Surabhi Dangi-Garimella, PhD

January 19th 2015

CML Updates: Defining MMR and Results of the DASISION Trial

Surabhi Dangi-Garimella, PhD

January 19th 2015

Sessions Report Phase 2 Results of Pomalidomide Combinations

Mary K. Caffrey

January 19th 2015

Promising Results for Elotuzumab Presented in Session on Multiple Myeloma

Mary K. Caffrey

January 19th 2015

Early Treatment, Monoclonal Antibodies Discussed in Multiple Myeloma

Mary K. Caffrey

January 19th 2015

ASH Presents Second Round of Tests, Treatments to Question Under Choosing Wisely Initiative

Mary K. Caffrey

January 19th 2015

Care Plans to Reduce Healthcare Utilization in Sickle Cell Disease

Surabhi Dangi-Garimella, PhD

January 19th 2015

Poster Presentations Cover Therapeutic Options in CML

Surabhi Dangi-Garimella, PhD

January 19th 2015

Pharmacists Ease Cancer Patients' Financial Burdens

A new study on the effects of cancer patients' financial burdens suggests that pharmacists can play a role in easing or preventing some of their stress.

January 19th 2015

Healthcare Costs in Need of Solutions: Experts at ASH Agree

Surabhi Dangi-Garimella, PhD

January 19th 2015

Session on Survivorship Outlines Surveillance Strategies in Non-Hodgkin Lymphoma

Mary K. Caffrey

January 19th 2015

Ibrutinib Demonstrates Significant Responses for Patients With Hard-to-Treat CLL/SLL, Phase 2 Data Show

Mary K. Caffrey

January 19th 2015

Study Suggests Method of Reducing Blood Clots Without Risking Bleeding

Mary K. Caffrey

January 16th 2015

UCLA Study Unveils Mechanism of Melanoma Drug Resistance

Researchers have uncovered how melanoma becomes resistant to a promising new drug combo therapy utilizing BRAF+MEK inhibitors in patients after an initial period of tumor shrinkage.

January 16th 2015

Study Indicates Improved Survival in CRC Despite Lower Surgery Rates

The research, published in JAMA Surgery, analyzed data collected from NCI's SEER database, between 1988 till 2010, on stage 4 CRC patients who had surgery or not for primary tumor resection. Survival data on these patients was then analyzed and associated with their surgical status.

January 16th 2015

Predictive Value of Diagnostic Tests

January 16th 2015

Development and Use of Diagnostic Testing

January 16th 2015

Predictive Value of Diagnostic Testing

January 16th 2015

Clinical Utility of Genomic Testing

January 16th 2015

Use of Molecular Tests That Assess Risk of Recurrence

January 15th 2015

Spanish Team Identifies Gene Variant Responsible for Susceptibility to Peripheral Neuropathy

The authors of the research say that this information could be especially valuable for the Spanish population: "Even though these variants are rare or not frequent in the population, their frequency is greater in Spain than in other countries."

January 15th 2015

Metabolic Syndrome A Significant Risk Factor in Endometrial Cancer, Study Finds

Overall, metabolic syndrome was associated with a 39 percent to 103 percent increased risk of endometrial cancer in women 65 and older, according to the study.

January 15th 2015

Patients With Metastatic Colorectal Cancer Having Less Surgery, Yet Survival Rates Improving

With the dawn of the modern era of new chemotherapeutic and biologic agents available for managing their disease, patients with metastatic colorectal cancer are undergoing less surgery for the removal of their primary tumors.

January 15th 2015

Can We Follow the European Model to Curb Drug Costs, Asks Dr Peter Bach

In an Ope-Ed in The New York Times , Peter Bach, MD, from the Memorial Sloan Kettering Cancer Center, questions the rising drug prices and contemplates solutions.

January 14th 2015

ASCO Staff Raising Healthcare Issues with Federal and State Legislators

Members of the ASCO Government Relations Committee are busy meeting Members of Congress as well as State Affiliates to address a number of healthcare issue early in the year.

January 14th 2015

Cancer Treatments the Next Big Area for Cost Saving Opportunities

Laura Joszt, MA

Involving the pharmacy benefits manager earlier in the decision-making process could lead to cost savings on cancer treatments, Express Scripts Chief Executive Officer George Paz said at the J.P. Morgan Healthcare Conference in San Francisco, California.

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