Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com

C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

By Jared Kaltwasser

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com

Novel Biomarkers May Inform Prognosis in SCLC

By AJMC Contributor

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

By Rose McNulty

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center

ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

By Mary Caffrey

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com

5 Key FDA Approval Dates Mark a Milestone-Filled May

By Brooke McCormick

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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March 14th 2014

Sorting Through Screening Protocols for Colorectal Cancer

Who should receive genetic counseling and screening for colorectal cancer (CRC)? And how early should annual colonoscopies happen once those at risk are identified? These are important questions with equally important and complex answers.

March 14th 2014

Protecting Bone Health During Cancer Care

Life-saving therapies that halt cancer can take a toll on the skeletal system, leaving survivors with bone loss or more serious injuries such as broken wrists, ribs, or hips. Watchful attention, screening, and therapy are needed to prevent these outcomes.

March 5th 2014

NCCN Updates Guidelines for Hereditary Colon Cancer Testing

The National Comprehensive Cancer Network (NCCN) has revised its medical guidelines to expand Lynch syndrome screening. Lynch syndrome is the most common cause of hereditary colon cancer in adults.

March 3rd 2014

Integrating Genetic Counseling Into an Oncology Practice Can Benefit High-Risk Families

Genetic counseling-including testing and risk assessment-is one of the most rapidly growing areas of oncology and has become the standard of care for patients with a personal and family history of breast, ovary, or colon cancer.

February 26th 2014

Ed Pezalla, MD, MPH, Discusses How Health Plans are Engaging Patients in Decision-Making

Ed Pezalla, MD, MPH, national medical director for pharmacy policy and strategy, office of the CMO, Aetna, says payers and health plans are preparing for patient-centered care by utilizing digital tools. Everything from virtual people to cost search tools are used to assist employed and general patient populations. Dr Pezalla says many of these tools will also be used in the public and private health insurance exchanges to help people make decisions as they purchase health plans.

February 25th 2014

Health Insurance Exchanges: Challenges and Opportunities for Pharma

Dennis Falci, MBA, director, US managed markets training, sales training and leadership development, Sanofi-Aventis SA, says it's no secret-Health Insurance Exchanges are a hot topic in health news.

February 24th 2014

Evolving Strategies for the Management of Multiple Myeloma: A Managed Care Perspective

Ira M. Klein, MD, MBA, FACP Ralph V. Boccia, MD, FACP Eric Cannon, PharmD, FAMCP William J. Cardarelli, PharmD Bo Gamble, BSBA Linda House, RN, BSN, MSM David H. Howard, PhD Mary Malloy, BA, CA

February 21st 2014

Cancer Patients Benefit from Early Palliative Care Intervention

Katie Sullivan

A 4-year study assessing the impact of early outpatient palliative care versus standard oncology care in a variety of advanced cancers found promising results. The researchers observed that when palliative care teams collaborated earlier in the course of illness, it improved patients' quality of life and satisfaction.

February 20th 2014

Clinical Utility in Prostate Cancer Testing

Katie Sullivan

Belgian cancer testing group MDxHealth recently announced an agreement with US health organization Prime Health Services to extend access to its prostate cancer test to 144 million insured people. MDxHealth suggests that collaboration will permit faster reimbursement for cancer testing.

February 20th 2014

Prostate Cancer Test Shows Role of 'Clinical Utility'

How Can Molecular Diagnostic Companies Show Value if Insurers Won't Pay?

February 17th 2014

Making Cancer Care More Affordable

Katie Sullivan

Researchers from the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center in Baltimore suggest that controlling the costs to treat cancer without increasing risk to patients requires a collaborative approach.

February 14th 2014

Three Ways to Make Cancer Care More Affordable

The malady of rising medical costs is acute, especially in the field of oncology. As populations age, new cancer cases are expected to reach 21.4 million in 2030, while treatment costs are projected to increase 40 percent by 2020.

February 14th 2014

Are Oncology Clinical Pathways Coming to Medicare?

Oncology clinical pathways have helped health plans deliver quality care while keeping an eye on costs. The lack of standardization in pathways can be cumbersome on a busy oncology practice. If Medicare adopts a pathways model, it could offer a framework for broader use.

February 13th 2014

FDA Grants Accelerated Approval for Ibrutinib for CLL

Surabhi Dangi-Garimella, PhD

The US Food and Drug Administration (FDA) on Wednesday granted accelerated approval for the expanded use of ibrutinib, marketed as Imbruvica, for chronic lymphocytic leukemia (CLL) patients who have previously received at least one therapy. The therapy is notable for its relative lack of toxic effects.

February 12th 2014

Value of the Mammogram Questioned

Katie Sullivan

The value of the mammogram is being questioned after 1 study found that the mortality rates resulting from breast cancer were the same in women who got screened and those who did not.

February 7th 2014

Expanded DNA Testing Might Allow Personalized Breast Cancer Treatment

Testing the entire genetic makeup -- or all the DNA -- of tumor cells from women with advanced breast cancer may help identify patients who could be helped by specific treatments, according to new research.

February 6th 2014

CVS Wins Plaudits for Vowing to Stop Tobacco Sales

Drugstore giant CVS Caremark's decision to stop selling tobacco products at its stores is being hailed as a victory among public health advocates, a move they predict will force CVS competitors to follow suit as they look to play a growing part in the delivery of the country's healthcare.

February 6th 2014

Co-payment Coupons and Patient Assistance Programs: Just 1 Piece of the Specialty Drug Management Puzzle

Pat Gleason, PharmD, FCCP, BCPS, director of health outcomes, Prime Therapeutics, and Shelley Sanchez, senior director of specialty product development, Prime Therapeutics, presented on 1 approach to managing the specialty drug benefit, which includes optimizing the use of PhARMA manufacturer coupons and patient assistance programs (PAPs).

February 6th 2014

Implications of the Health Insurance Exchange Marketplace and State Law Trends on Commercial Pharmacy

Presenters in this talk focused on how the creation of health insurance exchanges (HIEs) and other federal and state regulations will impact the provision and administration of pharmacy benefits.

February 6th 2014

Healthcare Industry Transformation to Meet Employer Demand for Managing Specialty Pharmacy Costs

According to Howard K. Crowley, head of pharmacy strategic initiatives, Aetna Pharmacy Management, a Towers Watson/ National Business Group on Health survey found that 29% of employers rank the rising costs of specialty drugs as a top challenge to keeping health benefit coverage affordable.

February 5th 2014

Pharmacy Benefit Management Institute Conference Highlights - Part 2

Katie Sullivan

This week AJMC is covering session highlights from the PBMI Annual Drug Benefit conference.

January 30th 2014

Chris Belmont Discusses How Hospitals Manage Health Information

Chris Belmont, vice president and chief information officer, MD Anderson Cancer Center, says the right timing and the right context are essential to effective health data management.

January 28th 2014

Karen Lewis, MS, MM, CGC, Discusses Oncology and Genetic Testing

Karen Lewis, MS, MM, CGC, says the goals of Healthy People 2020 are developed by looking at a variety of key areas in healthcare, and then choosing the most actionable items to improve the overall health of the general population.

January 27th 2014

Doctors, Older Patients Rethink Cancer Treatments

Experts in treating older cancer patients say it's important to think of each patient individually, not to assume that because someone has reached a certain age that he or she isn't going to be able to withstand surgeries, radiation or chemotherapy.

January 23rd 2014

COA and ASCO Issue Joint Statement on Oncology Payment Reform

COA and ASCO are issuing a joint statement on payment reform in cancer care. The goal is to improve the lives of individuals with cancer, in part by developing and supporting payment systems based on evidence-based medicine and measures of quality and value in cancer care.

January 22nd 2014

Drugmakers See Innovation Justifying Further Price Rises

As U.S. consumers are asked to shoulder more prescription drug costs, drugmakers say prices for brand-name medicines will keep rising, mainly because use of their products reduces other healthcare costs.

January 21st 2014

Amy Berman, BS, RN, Discusses Patient-Centered Oncology Care

Amy Berman, BS, RN, says that all too often, people end up in the hospital because they don't know where else to go for treatment.

January 17th 2014

Custom-Fit Treatments for Prostate Cancer

In a bid to improve treatment for men with high-risk prostate cancer, some researchers want to take a page from the playbook for breast cancer.

January 16th 2014

Scott Ramsey, MD, PhD, on Health Economics and Outcomes Research in Oncology

Scott Ramsey, MD, PhD, Fred Hutchinson Cancer Research Center, says that right now, only a small portion of health economics and outcomes research (HEOR) fits into the oncology model.

January 13th 2014

Comorbidities and Cardiovascular Disease Risk in Older Breast Cancer Survivors

Reina Haque, PhD, MPH Marianne Prout, MD Ann M. Geiger, PhD Aruna Kamineni, PhD Soe Soe Thwin, PhD Chantal Avila, MA Rebecca A. Silliman, MD, PhD Virginia Quinn, PhD Marianne Ulcickas Yood, DSc

Effective management of the comorbidities of diabetes and hypertension may increase survival in older breast cancer survivors.

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