Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com

C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

By Jared Kaltwasser

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com

Novel Biomarkers May Inform Prognosis in SCLC

By AJMC Contributor

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

By Rose McNulty

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center

ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

By Mary Caffrey

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com

5 Key FDA Approval Dates Mark a Milestone-Filled May

By Brooke McCormick

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

October 28th 2020

A Closer Look at 3 Oncology Payment Reform Projects

Mary Caffrey

Evolution and collaboration are the fundamentals of bringing oncology payment reform plans to fruition, say 3 professionals on the front lines.

October 28th 2020

Cancer Does Not Stop for COVID-19, but Reform Becomes a Challenge

Rose McNulty

During a session on day 1 of the Community Oncology Alliance (COA) Virtual Payer Exchange Summit on Oncology Payment Reform, a panel of experts discussed the ways COVID-19 continues to impact cancer care and payment reform.

October 25th 2020

Dr Andre Goy Discusses Potential Benefits of Earlier Use of CAR T Therapies

Andre Goy, MD, chairman, director, and chief of the Division of Lymphoma at John Theurer Cancer Center in Hackensack, NJ, discussed the potential benefits of using CAR T-cell therapies as a second-line treatment.

Avalere Webinar on Oncology Care and Payment Reform

October 22nd 2020

Experts Discuss Oncology Care and Payment Reform in Avalere Webinar

Rose McNulty

Experts in cancer care and payment discussed the future of oncology care in a panel discussion hosted by Avalere Health on October 21, 2020.

October 21st 2020

Dr David Jackman on Dana Farber's Clinical Pathway Development Process

At Dana Farber Cancer Institute, essential steps to developing clinical pathways include engaging physicians to buy-in, finding the optimal platform to store data, and displaying resulting content in a supportive and efficient way.

October 16th 2020

Hodgkin Lymphoma Patients Face Noncancer Death Risk Despite Modern Therapies

Rose McNulty

A study and accompanying editorial from the Journal of Clinical Oncology found that Hodgkin lymphoma survivors still face a higher risk of non-cancer death than the general population.

Sara L. Douglas, PhD, RN, Case Western Reserve University

October 11th 2020

Dr Sara Douglas: Distance Caregivers of Patients With Cancer Have Distinct Needs

Distance caregivers have unique needs, explained Sara L. Douglas, PhD, RN, the Gertrude Perkins Oliva Professor in Oncology Nursing, associate dean for research, the Frances Payne Bolton School of Nursing, Case Western Reserve University.

October 10th 2020

Phase 2 Trial to Study Palbociclib in Early Stage Breast Cancer Based on ctDNA Monitoring

Rose McNulty

Natera’s Signatera ctDNA test will determine study eligibility and treatment effectiveness in HR-positive, HER2-negative breast cancer patients.

October 4th 2020

Dr Karen Winkfield on Improving Minority Access, Education for Precision Oncology

Addressing gaps in testing and education within precision oncology can assist in improving access to patients of color and other underserved populations.

September 30th 2020

Counties Experiencing Persistent Poverty Have Higher Cancer Mortality Rates

Gianna Melillo

Throughout the United States, counties experiencing persistent poverty have disproportionately higher rates of cancer mortality, according to a study published in Cancer Epidemiology, Biomarkers & Prevention.

Maura Abbott, PhD, AOCNP, CPNP, RN, Columbia University School of Nursing

September 29th 2020

Dr Maura Abbott Explains How Vaccine Form Determines Patient Contraindications

Form will determine in which patient populations, and why, a vaccine is not indicated for administration, said Maura Abbott, PhD, AOCNP, CPNP, RN, assistant professor of nursing at the Columbia University School of Nursing.

September 28th 2020

Addressing Cancer Disparities Requires Asking Questions and Putting Aside Assumptions

Laura Joszt, MA

Speakers at Patient-Centered Oncology Care® highlighted injustices in the US health care system, the risk of financial toxicity, and how providers can do a better job to ensure their patients achieve health equity, during a panel discussion.

September 23rd 2020

Dr Kashyap Patel Discusses COVID-19 Implications for PCOC® 2020

The uncertainties precipitated by the coronavirus disease 2019 (COVID-19) pandemic around cancer care delivery are a challenging topic to be further addressed at this year’s Patient-Centered Oncology Care® 2020 virtual meeting.

September 23rd 2020

How Oncology Practices Are Identifying, Addressing Health Needs Amid Pandemic

Through risk stratification and identifying social determinants of health, oncology practices are monitoring the direct and indirect effects of the pandemic, noted Jenifer Leaf Jaeger, MD, MPH, senior medical director of HealthEC.

September 22nd 2020

Dr Joseph Alvarnas on Opportunities Presented by Virtual Format of PCOC® 2020

Through this year's virtual format for Patient-Centered Oncology Care® 2020, participants will be able to attend sessions, ask questions, and gain insight in an immediate, efficient way.

September 19th 2020

More Coffee, Longer Survival? Study Highlights Benefit in Metastatic Colon Cancer

Allison Inserro

Patients with advanced colon cancer who drank 4 or more cups of coffee a day had 36% improved survival odds.

September 18th 2020

AACR Report Highlights Disparities in Cancer and the Need for Health Equity

Laura Joszt, MA

Although innovations in cancer treatment have driven down overall cancer death rates and increased the number of survivors living with cancer, that progress has not benefitted everyone with cancer equally.

September 9th 2020

Equity in Care Delivery Still at Top of PCOC 2020 Agenda, Amid “Undue Burden”

Mary Caffrey

Drs Joseph Alvarnas and Kashyap Patel, co-chairs of Patient-Centered Oncology Care® 2020, discuss what attendees can look forward to at the September 25 meeting.

September 7th 2020

Combatting COVID-19 With Real-World Evidence

Jennifer B. Christian, PharmD, MPH, PhD Matthew W. Reynolds, PhD

A vaccine isn’t the panacea many assume it will be. Even when it becomes available, the virus won’t go away. Real world evidence will be needed to guide decision making.

September 5th 2020

Uptake of Palliative Care in Liver Cancer Needs Improvement, Report Says

Allison Inserro

Hepatocellular carcinoma is rising, and so is the need for increased awareness and use of palliative care, say the authors of a recent review.

August 28th 2020

Tafasitamab Plus Lenalidomide Added to NCCN Guidelines

AJMC Staff

NCCN added tafasitamab plus lenalidomide to their oncology practice guidelines for patients with relapsed or refractory DLBCL not otherwise specified.

August 25th 2020

When the Topic Is Dying: A Conversation With Kashyap Patel, MD

Mary Caffrey

Kashyap Patel, MD, CEO of Carolina Blood and Cancer Care, associate editor of Evidence-Based Oncology, and vice president of the Community Oncology Alliance, discusses his new book.

August 24th 2020

Psychosocial Support for Patients With Cancer Waning as COVID-19 Pandemic Continues

Jaime Rosenberg

A recent survey showed the disruption in cancer care as a result of the pandemic is worrying professionals who provide psychosocial support to patients.

August 16th 2020

Sidebar: CMS Seeks to Fix Medicaid Best-Price Barriers in Value-Based Contracting for High-Cost Therapies in Medicaid

Mary Caffrey

Proposed CMS rules would make it easier for state Medicaid programs to smooth the way for value-based contracts for high-cost gene therapies.

August 13th 2020

Amid Effort to Shrink Cancer Disparities, Authors Say COVID-19 Will Widen Them

Mary Caffrey

As the American Society of Clinical Oncology calls for more aggressive efforts to bring equity to cancer care, authors in JAMA Oncology say COVID-19 is creating wider gaps.

August 2nd 2020

Tafasitamab Combination Approved for Adults With R/R DLBCL

Mary Caffrey

A new treatment option is approved for patients with a common form of non-Hodgkin lymphoma who cannot have an autologous stem cell transplant.

July 21st 2020

American Oncology Network, LLC Announces New Advisory Board Chair and Executive Committee

The American Oncology Network, LLC, has added 5 medical oncologists to its Executive Committee.

July 20th 2020

Access to Care: Burris Says United With Our Patients, We Accelerate Progress Together

Maggie L. Shaw

“We’ve had advancements, but we need to go faster,” said ASCO President Howard A. "Skip" Burris III, MD, as he stressed the importance of advancing therapies for better patient outcomes by addressing obstacles to patients’ care. “Access to care, access to clinical trials, and access to information are really key.”

July 14th 2020

Florida Cancer Specialists Names New CEO

Nathan H. Walcker will succeed Brad Prechtl on August 1, 2020.

July 1st 2020

Don't Delay Cancer Care During COVID-19 Crisis

Amy McNally, MD

Federal and state officials have implemented policies and safeguards to slow transmission of the virus. Most troubling were state moratoriums on “elective” surgical procedures.

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