Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com

C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

By Jared Kaltwasser

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com

Novel Biomarkers May Inform Prognosis in SCLC

By AJMC Contributor

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

By Rose McNulty

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center

ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

By Mary Caffrey

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com

5 Key FDA Approval Dates Mark a Milestone-Filled May

By Brooke McCormick

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Watch Now

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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June 19th 2020

From the Editor-in-Chief: Bigger Questions of Systems, Viruses, and the Lives of Real People

Joseph Alvarnas, MD

As I recall the early days of the HIV/AIDS pandemic, what stands out most is its profound human cost and the courage of those who helped our society transcend it. We are in the midst of a time in which the human toll of COVID-19 and the enormity of the path ahead are clear.

June 17th 2020

Conference Coverage: Community Oncology Alliance

Maggie L. Shaw Mary Caffrey

Coverage from the Community Oncology Alliance Virtual Meeting, held April 23-24, 2020.

June 17th 2020

How to Optimize Cancer Therapy When Coronavirus Hits the Fan

Afsaneh Barzi, MD, PhD Sarmad Sadeghi, MD, PhD

The American Society of Clinical Oncology recommends that cancer survivors who have completed their treatment and are under surveillance with no known evidence of disease are to be kept out of care facilities to avoid developing COVID-19.

June 16th 2020

FDA Grants Accelerated Approval to Lurbinectedin in Metastatic Small Cell Lung Cancer

AJMC Staff

Investigators reported in Lancet Oncology that second-line treatments are needed in small cell lung cancer, as few options exist for these patients once first-line therapy fails.

June 11th 2020

Claims Identification of Patients With Severe Cancer-Related Symptoms

Richard W. DeClue, PhD, MPH Dana Drzayich Antol, MS Adrianne W. Casebeer, PhD, MS, MPP Todd Michael, PharmD, RPh Marina Sehman, PharmD Andrew Renda, MD, MPH Sarika Ogale, PhD Stephen Stemkowski, PhD, MHA Bryan Loy, MD

The authors established a claims-based mechanism for identifying patients with lung cancer with more severe patient-reported cancer-related symptoms who could benefit from engagement with health care programs.

June 11th 2020

Aaron Lyss on What the Next Oncology Payment Model Should Include

Benchmarking, accountability, bilateralism, and scalability are the 4 parameters critical to successful alternative payment models in oncology, said Aaron Lyss, MBA, director of strategy and business development at Tennessee Oncology.

June 6th 2020

Aaron Lyss Outlines Lessons Learned From Data Analytics

In each performance period of the Oncology Care Model for which we've received data, we've seen different aspects of care that we can improve upon in the following 6 months, said Aaron Lyss, MBA, director of strategy and business development at Tennessee Oncology.

May 30th 2020

Aaron Lyss Discusses Practice Transformation Under the OCM

The Oncology Care Model (OCM) has helped practices develop their capacity to use data for continuous quality improvement, said Aaron Lyss, MBA, director of strategy and business development at Tennessee Oncology.

May 29th 2020

Lili Brillstein on Mandatory, Voluntary Payment Models

There will never be all mandatory payment models or all value-based models, but we can craft a value-based model around just about anything as long as everybody agrees on what the criteria is, said Lili Brillstein, CEO of Brillstein Collaborative Consulting, and former Director for Episodes of Care at Horizon Blue Cross Blue Shield of New Jersey.

May 18th 2020

Lili Brillstein Outlines Challenges of Incorporating Value-Based Care in Oncology

New technologies and quick drug approvals contribute to the challenges of incorporating value-based care in oncology, said Lili Brillstein, CEO of Brillstein Collaborative Consulting, and former Director for Episodes of Care at Horizon Blue Cross Blue Shield of New Jersey.

May 7th 2020

Kelly Filchner Highlights Obstacles, Benefits of Transitioning Patients From Cancer Care to PCPs

Raising awareness on the involvement of primary care providers can assist cancer survivors in transitioning from oncology care, said Kelly Filchner, MSN, director at Fox Chase Cancer Center Partners.

May 5th 2020

Dr Ray Page on Balancing Innovations and Cost in Cancer Care

Transformational changes in cancer care can bring forth important innovations, but all those come at a cost, said Ray Page, DO, PhD, president and director of research at The Center for Cancer and Blood Disorders.

May 1st 2020

AJMC® in the Press, May 1, 2020

AJMC Staff

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

May 1st 2020

This Week in Managed Care: May 1, 2020

The Supreme Court says insurers are owed $12 billion under the Affordable Care Act; a study finds those with cancer are at higher risk from coronavirus disease 2019 (COVID-19); a survey shows millions would avoid seeking care for COVID-19 due to cost.

May 1st 2020

Dr Ray Page Discusses Delays in Reporting OCM Results

Delays in reporting Oncology Care Model results from performance periods creates tremendous uncertainty, said Ray Page, DO, PhD, president and director of research at The Center for Cancer and Blood Disorders.

April 30th 2020

Kelly Filchner Notes Barriers Preventing Integration of Primary Care Providers Into Oncology Care

Innovations to promote communication between primary care providers, oncologists are vital to delineate distinct roles in oncology patient management, said Kelly Filchner, MSN, director at Fox Chase Cancer Center Partners.

April 25th 2020

PBMs and Community Oncology: "We Just Can't Let Them Get Away With What They're Doing"

Mary Caffrey

Despite the immediate distraction from coronavirus disease 2019 (COVID-19), panelists at the 2020 Virtual Community Oncology Conference said community oncologists must keep pressure on pharmacy benefit managers (PBMs) as the 2020 campaign heats up—lest they lose the momentum to rein PBM practices within the umbrella of drug pricing reform.

April 25th 2020

COA Consensus: Telemedicine Is Here to Stay, but Practice Transformation Could Stall

Mary Caffrey

The bright spot of telemedicine's success during the coronavirus disease 2019 pandemic cannot overshadow the stresses on patients and practices, which will both have ongoing challenges when the pandemic ends, said panelists during a legislative update on day 2 of the 2020 Virtual Community Oncology Conference, convened by the Community Oncology Alliance.

April 24th 2020

This Week in Managed Care: April 24, 2020

This week, the top managed care news included HHS' plans to allocate the remaining $70 billion in COVID-19 funding to providers; an analysis finding aggressive social distancing measures economically justified; highlights from this week's virtual Community Oncology Conference.

April 24th 2020

Dr Michael Diaz Discusses Feedback From Practices in 2-Sided Risk

Oncology practices in 2-sided risk arrangements have reported mixed results, pointing to the need for more time to make the transition, said Michael Diaz, MD, president of Community Oncology Alliance.

April 23rd 2020

Kelly Filchner on Importance of PCPs in Improving Coordination of Care for Cancer Survivors

Many patients when they start their cancer therapy get so ingrained in the cancer world that their oncologist just becomes their main point of contact, but we have to do a better job at letting the patients know that the PCP still is an integral part of their care, said Kelly Filchner, MSN, director at Fox Chase Cancer Center Partners.

April 22nd 2020

Dr Dinesh Kapur on Value of Community Oncology, Developing AI Tools for Patient Care

Allison Inserro

The American Journal of Managed Care® (AJMC®) recently spoke with Dinesh Kapur, MD, of Eastern Connecticut Hematology and Oncology, also known as ECHO, an advanced community oncology conference. Kapur spoke about how the value of community oncology, clinicial trials, and how staff are spending remote work days developing artificial intelligence (AI) tools for predictive patient analytics to improve care.

April 20th 2020

COVID-19 Upends Drug Purchasing Patterns, and More Disruption Likely, IQVIA Expert Says

Mary Caffrey

Douglas M. Long, MBA, vice president of industry relations for IQVIA, surveyed the effects of COVID-19 as he kicked off AMCP eLearning Days, a webinar series held in place of the annual meeting of the Academy of Managed Care Pharmacy (AMCP).

April 20th 2020

Kathy Oubre: Witnessing Growing Cancer Survivorship Is a Privilege

Maggie L. Shaw

In this preview interview for this year’s virtual 2020 Community Oncology Conference, The American Journal of Managed Care® speaks with Kathy Oubre, MS, chief operating officer of Pontchartrain Cancer Center in Louisiana, on why it is her privilege to work with patients who have cancer, as well as her thoughts on telehealth after the pandemic and why being in a hurricane-prone area necessitates healthcare that is flexible.

April 18th 2020

Dr Lalan Wilfong: Groundbreaking Research to Be Presented at COA's 2020 Virtual Conference

Individuals should register for Community Oncology Alliance's virtual meeting to hear "amazing" speakers present groundbreaking research, said Lalan Wilfong, MD, medical oncologist and vice president of value-based care and quality programs at Texas Oncology.

April 15th 2020

Dr Michael Diaz Outlines Important Lessons Learned From the OCM

Networking with other practices, sharing ideas, and getting physicians involved in the process can aid community practices moving to alternative payment models (APMs), said Michael Diaz, MD, president of Community Oncology Alliance.

April 12th 2020

Medical World News: April 2020

AJMC Staff

Policy, clinical, and targeted therapy updates in oncology.

April 12th 2020

CONFERENCE COVERAGE: Association of Community Cancer Centers 2020

Maggie L. Shaw

The Association of Community Cancer Centers held its 46th Annual Meeting and Cancer Center Business Summit March 4 to 6 in Washington, DC.

April 11th 2020

In Florida, Serving the Senior Population in Oncology Means Working Together

Mary Caffrey

“Quest for Value: Advancing Oncology Value-based Care,” this year’s first installment in the Institute for Value-Based Medicine (IVBM) from The American Journal of Managed Care®, zeroed in seniors, a population that’s growing not just in Florida but across the United States. Older Americans are more likely to develop cancer, but thanks to better detection and treatment, they are more likely to survive cancer, too.

April 8th 2020

NCCN Guidelines May Aid US Biosimilar Uptake, Cancer Experts Say

Skylar Jeremias

Payers view the National Comprehensive Cancer Network (NCCN) guidelines as a gold standard for making reimbursement decisions, according to a panel of experts who spoke recently about biosimilar uptake.

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