Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com

C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

By Jared Kaltwasser

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com

Novel Biomarkers May Inform Prognosis in SCLC

By AJMC Contributor

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

By Rose McNulty

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center

ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

By Mary Caffrey

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com

5 Key FDA Approval Dates Mark a Milestone-Filled May

By Brooke McCormick

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

December 19th 2019

Future of BCC and CSCC Therapy

December 19th 2019

Second-Line Systemic Treatment of BCC

December 19th 2019

Systemic Therapy in BCC

December 19th 2019

Electing for Surgery in the Management of BCC

December 19th 2019

Overview of Basal Cell Carcinoma

December 19th 2019

Toxicity Profile and Pseudoprogression

December 19th 2019

PD-1 and Other Systemic Treatment Options for CSCC

December 19th 2019

Using Immunotherapy in CSCC

December 19th 2019

Systemic Treatment of CSCC

December 19th 2019

Standard of Care for CSCC

December 19th 2019

Overview of Cutaneous Squamous Cell Carcinoma

December 18th 2019

Radiation Oncologist Discusses Concerns With Incoming CMS Payment Model

Allison Inserro

As CMS prepares to move forward with new models of value-based cancer care, a radiation oncologist, speaking at the Institute for Value-Based Medicine®, discussed her findings regarding whether accountable care models had an effect on cancer care spending.

December 18th 2019

Hope and Some Skepticism Whether Oncology Payment Models Will Work

Allison Inserro

Coverage from the Institute for Value-Based Medicine® session held in Nashville, Tennessee.

December 18th 2019

Risk of Heart Failure Greater in Patients With AML, ALL on Anthracyclines

Maggie L. Shaw

In cases of acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL), there is a greater risk of symptomatic heart failure in the first year following initiation of anthracycline treatment.

December 17th 2019

Government-Insured Patients With Breast Cancer Face a Higher Risk of Death

Gianna Melillo

Patients with breast cancer who have government insurance face a higher risk of death, according to a retrospective study presented at the 2019 San Antonio Breast Cancer Symposium on December 13.

December 17th 2019

From the Editor-in-Chief: Lead, Follow, or Get Out of the Way

Joseph Alvarnas, MD

Dr Alvarnas is editor-in-chief of Evidence-Based Oncology.™ He is vice president of Government Affairs, senior medical director for Employer Strategy, and associate clinical professor, Hematology & Hematologic Cell Transplantation, City of Hope, Duarte, Califonia.

December 16th 2019

Provider Perspective: Stephen M. Schleicher, MD, MBA, Addresses Accountability Versus Control in Oncology Care First

Mary Caffrey

An article Schleicher co-wrote in JAMA Oncology, which appeared the day before the announcement of Oncology Care First, offered insights into the need for changes to the original OCM.

December 16th 2019

Provider Perspective: Kashyap Patel, MD, Sees Collaboration Going Into Oncology Care First

Mary Caffrey

Kashyap Patel, MD, the chief executive officer of Carolina Blood and Cancer Care Associates—a leading OCM practice—and associate editor of Evidence-Based Oncology™ (EBO), said he’s optimistic about Oncology Care First.

December 16th 2019

Can Cancer Care Lead the Way Toward a Value-Based Future?

Keely Macmillan, MPH

A senior vice president of Archway Health discusses challenges and opportunities of the proposed Oncology Care First model.

December 12th 2019

Anthracycline, Radiation Treatment for Childhood Cancer Shown to Increase Risk of Adult Breast Cancer

Maggie L. Shaw

There was a 37% increase in childhood cancer survival between 1975 and 2010. With more children receiving chemotherapy and radiation to treat their diseases, leading to more survivors, awareness has grown of the belated effects of those treatments once patients reach adulthood.

December 11th 2019

Outcome Measures for Oncology Alternative Payment Models: Practical Considerations and Recommendations

Jakub P. Hlávka, PhD Pei-Jung Lin, PhD Peter J. Neumann, ScD

This review presents a set of evidence-based outcome measures for oncology alternative payment models, drawing on evidence from existing and proposed quality measures.

December 11th 2019

Supplemental MRI of Very Dense Breast Tissue Finds Early Cancers, at Higher Risk of False Positives

Gianna Melillo

A recent study published in The New England Journal of Medicine says that women with dense breast tissue who undergo supplemental magnetic resonance imaging (MRI) tests have lower rates of interval cancers than those who receive only mammography tests, although they also had higher rates of false positive tests.

December 8th 2019

Jennifer Atkins Describes Blue Cross Blue Shield's Commitment to Innovations in Oncology

Blue Cross Blue Shield is dedicated to maintaining local relationships to ensure they can provide the best care continuum to patients, said Jennifer Atkins, MBA, vice president of Network Solutions at Blue Cross Blue Shield.

December 7th 2019

NHS Staffing Shortages Behind Delays in Cancer Diagnoses for Patients in UK

Gianna Melillo

Patients waited about 2 months longer than necessary for a cancer diagnosis in the United Kingdom, according to a study published this week.

December 4th 2019

Patients With Chemotherapy-Induced Cardiomyopathy Show Improvements in LVEF After Cardiac Resynchronization Therapy

Maggie L. Shaw

Heart issues in patients with cancer and survivors can present themselves months or years after treatment.

November 29th 2019

This Week in Managed Care: November 29, 2019

This week, the top managed care news included research that may hold the key to slowing progression of multiple sclerosis; Humana says it is saving billions of dollars through value-based care; the challenges of rural healthcare delivery.

November 28th 2019

Top 5 AJMC® Articles of November 2019

Here are the top 5 articles for the month of November.

November 27th 2019

AJMC® Research Roundup: November 2019

Here are 5 interesting findings from the November 2019 issue of AJMC®.

November 27th 2019

ASCO Updates Patient-Centered Oncology Payment Model

Maggie L. Shaw

After a request for additional input from oncologists, practice administrators, payer representatives, and experts in physician payment and business analysis, ASCO has issued updated guidance on PCOP. With CMS’ Oncology Care Model set to end in 2021, the current draft of ASCO’s Community-based Oncology Medical Home model would be an option to take its place.

November 25th 2019

Dr James Hamrick Offers Advice for Providers Looking to Implement Patient Engagement Programs

The biggest advice I would give to practices and care teams trying to really engage patients more is be innovative, explained James Hamrick, MD, senior medical director at Flatiron Health.

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