Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com

C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

By Jared Kaltwasser

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com

Novel Biomarkers May Inform Prognosis in SCLC

By AJMC Contributor

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

By Rose McNulty

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center

ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

By Mary Caffrey

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com

5 Key FDA Approval Dates Mark a Milestone-Filled May

By Brooke McCormick

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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November 22nd 2019

Dr Joshua Ofman: Early Detection of Cancer Is Vital to the Progression of Oncology Care

GRAIL has generated enormous innovations in oncology care over the past 2 decades and will continue this trend through exploring 1 of oncology’s biggest opportunities, early detection of cancer, said Joshua Ofman, MD, chief of Corporate Strategy and External Affairs at GRAIL Inc.

November 20th 2019

What We're Reading: Vaping Ban Bill; Anal Cancer Rates; Medical Bill Protections

AJMC Staff

A House committee approves a bill to ban all flavored tobacco products; anal cancer rates are on the rise; the debate continues over competing healthcare measures.

November 16th 2019

Nina Chavez on Whether Biosimilars Will Offer Cost Savings in Oncology

Nina Chavez, MBA, FACMPE, chief operating officer, New Mexico Oncology Hematology Consultants, Ltd., discusses if she thinks biosimilars will play a role in lowering costs in coming years.

November 13th 2019

Dr James Hamrick on Challenges With Understanding, Acting on What Constitutes Value for Patients

James Hamrick, MD, senior medical director at Flatiron Health, discusses some of the biggest challenges with trying to understand what constitutes value for patients and then turning that into actionable information.

November 12th 2019

Erich Mounce: Providing Relevant Data to Provider Practices Encourages Growth

Providing providers with relevant data on quality of care and profitability allows them to adjust their practices efficiently, said Erich Mounce, chief operating officer, OneOncology.

November 12th 2019

Multimodality Cancer Care and Implications for Episode-Based Payments in Cancer

Suhas Gondi, BA Alexi A. Wright, MD, MPH Mary Beth Landrum, PhD Jose Zubizarreta, PhD Michael E. Chernew, PhD Nancy L. Keating, MD, MPH

Most patients receiving multimodality cancer care receive care from different practices. Therefore, episode-based payments in oncology must hold multiple providers accountable for costs and quality.

November 12th 2019

Money, Mandate Are Keys to FDA's Drive for Use of Real-World Evidence, Gottlieb Says

Mary Caffrey

Former FDA Commissioner Scott Gottlieb, MD, who has returned to the American Enterprise Institute, left FDA in April after 2 whirlwind years that saw a record pace of approvals and policy actions that covered everything from high drug prices to teen vaping. He spoke Friday in Philadelphia at Patient-Centered Oncology Care®, the annual meeting of oncology reimbursement stakeholders held by The American Journal of Managed Care®.

November 10th 2019

Podcast: This Week in Managed Care—Life After the Oncology Care Model and Other Health News

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

November 8th 2019

Tracy Bahl: Unifying Interests to Improve Oncology in a Consolidated Way Can Improve Patient Care

Consolidating unified interests for improved cancer care can enhance efficiency and quality of care for patients, said Tracy Bahl, MBA, president and chief executive officer of OneOncology.

November 8th 2019

This Week in Managed Care: November 8, 2019

This week, the top managed care news included CMS started planning for life after the Oncology Care Model; a judge blocked a rule requiring immigrants to have health coverage; Election Day brought news for Medicaid work rules.

November 6th 2019

Electronic PROs a Proposed Feature of Successor Model in Oncology Care

Mary Caffrey

Oncology care groups have praised the multipayer Oncology Care Model (OCM) for transforming cancer care through greater focus on care navigation, palliative care, survivorship, and keeping patients out of the emergency department. But there are complaints that practices can be penalized for elements beyond their control—notably, the soaring cost of state-of-the-art immunotherapies that were not on the market when the OCM was conceived.

November 5th 2019

Bobby Green: Data Utilization Crucial in Choosing Methods of Effective Care

By continuing to gather data on specific genomic data and profiles, we can heighten knowledge of applied treatment information on patient conditions, said Bobby Green, MD, chief medical officer at Flatiron.

November 1st 2019

Dr Lawrence Shulman Outlines the Potential of Value-Based Care in Oncology

Lawrence N. Shulman, MD, director of the Center for Global Cancer Medicine at the Abramson Cancer Center, and professor of Medicine at the Hospital of the University of Pennsylvania, discusses how value-based care can advance the quality of oncology care that it isn't currently.

October 31st 2019

Bradley Prechtl Explains the Importance of Dispelling Patient Misconceptions of Clinical Trials

I think there is a lot of confusion, especially in the patient community, about clinical research., explained Bradley Prechtl, MBA, chief executive officer of Florida Cancer Specialists and the American Oncology Network.

October 31st 2019

Dr Jeremy Whalen Outlines the Development and Application of Medical Strategies for Efficient Care

Referencing patients as attributable examples of necessary care has assisted in developing strategies for pharmacy and medication benefits, said Jeremy Whalen, PharmD, BCOP, Specialty Clinical Program Director for Oncology at Prime Therapeutics.

October 30th 2019

Unlocking Data Key to Value-Based Agreements With Pharma

Mary Caffrey

Proposed changes to the Stark Law that would make collaboration easier have purposely excluded pharmaceutical manufacturers, according to speakers at the Community Oncology Alliance Payer Exchange Summit.

October 30th 2019

CMS' Innovation Leader Touts Value of Physician Feedback

Mary Caffrey

The Oncology Care Model is a leading innovation in the move from fee-for-service to value-based reimbursement in large part because CMS has made adjustments based on physician feedback, according to an agency official who addressed the Community Oncology Alliance Payer Exchange Summit.

October 29th 2019

Moving Into the Future of Cancer Care Through OCM 2.0

Mary Caffrey

What would a successor to the Oncology Care Model (OCM) look like? Community oncologists discuss at the Payer Exchange Summit sponsored by the Community Oncology Alliance.

October 28th 2019

Erich Mounce: Investing in a Robust Electronic Medical Record Key to Measuring Practice Performance

Even without input from the Oncology Care Model, community practices can measure performance data through a robust electronic medical record like Flatiron, said Erich Mounce, chief operating officer, OneOncology.

October 25th 2019

From the Editor-in-Chief: Reality Isn't That Simple

Joseph Alvarnas, MD

Reality seems so simple. We just open our eyes and there it is. But that doesn’t mean it is simple. Penn and Teller

October 25th 2019

Kathy W. Oubre Outlines the Full Breadth of Financial Assistance Offered at Pontchartrain Cancer Center

As costs for cancer care continue to rise, Pontchartrain Cancer Center does benefit and cost analyses for all patients before they start therapy and also takes into account any social needs they might have, said Kathy W. Oubre, MS, chief operating officer at Pontchartrain Cancer Center.

October 23rd 2019

Bobby Green: Communicating With Oncologists Increases Understanding of Clinic Needs

By communicating with oncologists, Flatiron enhances their understanding of potential issues in clinics and how technology can enhance clinical workflow, said Bobby Green, MD, chief medical officer at Flatiron.

October 23rd 2019

Tesh Khullar Outlines Efforts Needed to Make Sure Providers Are Comfortable Prescribing Biosimilars

Tesh Khullar, senior vice president & advisor, Flatiron Health, explains what efforts are needed to make sure providers are comfortable prescribing biosimilars.

October 20th 2019

Dr Michael Kolodziej on Succeeding in the Evolving Cancer Care Landscape

We learn most when we have benchmarking and we can examine our own processes of care, explained Michael Kolodziej, MD, vice president and chief innovation officer at ADVI Health, Inc.

October 20th 2019

Podcast: This Week in Managed Care—New Long-term Opioid Use Guidelines and Other Health News

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

October 20th 2019

AJMCtv October 2019

Jaime Rosenberg

AJMC®TV interviews let you catch up on what’s new and important about changes in healthcare, with insights from key decision makers—from the clinician, to the health plan leader, to the regulator.

October 20th 2019

Medical World News

AJMC Staff

Managed care and clinical updates in cancer treatment.

October 20th 2019

Institute for Value-Based Medicine: Philadelphia Region, Fall 2019

Matthew Gavidia Jaime Rosenberg

Speakers from major area cancer centers and Independence Blue Cross addressed progress in implementing value-based care initiatives during a session held September 19, 2019.

October 20th 2019

Conference Coverage: NCCN Policy Summit September 2019

Jaime Rosenberg

Speakers at the September 12, 2019, Policy Summit of the National Comprehensive Cancer Center, held in Washington, DC, addressed what practices have learned from experience with the Oncology Care Model and what steps must occur to standardize patient reported outcomes to incorporate them into reporting.

October 18th 2019

AJMC® in the Press, October 18, 2019

AJMC Staff

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

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