Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com
C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com
Novel Biomarkers May Inform Prognosis in SCLC

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com
Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center
ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com
5 Key FDA Approval Dates Mark a Milestone-Filled May

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

Hands holding green lymphoma ribbon | Image credit: sulit.photos - stock.adobe.com
October 9th 2024

Childhood Lymphoma: Raising Awareness for Early Detection and Better Outcomes

Pearl Steinzor
It is important to educate and bring awareness to childhood lymphoma, its symptoms, treatment options, and the need for support.
Cancer screening | Image credit: kenchiro168 - stock.adobe.com
October 3rd 2024

Fear of Recurrence Is Common Among Adult Survivors of Childhood Cancer

Pearl Steinzor
Adults who survived childhood cancer experience elevated fear that their primary cancer will recur or that a subsequent malignant neoplasm will develop, according to a new study.
Managing AEs of Cannabis Use in Patients With Cancer
September 29th 2024

Managing AEs of Cannabis Use in Patients With Cancer

Laura Joszt, MA
There are some short-lived, common adverse events for patients using cannabis, but also some more dangerous, less common ones in chronic users, explained Marie Parish, PharmD, BCOP, of Mayo Clinic.
dr linda bosserman
September 27th 2024

Expanding Access to Innovative Cancer Treatments

Brooke McCormick
Linda Bosserman, MD, PhD, FASCO, FACP, of City of Hope, discusses the implementation of cutting-edge cancer treatments, emphasizing the need for effective information sharing and collaboration to improve cancer care access for diverse populations.
dr andrew leitner
September 26th 2024

Increasing Access to Supportive Oncology Care Can Drive Health Equity

Brooke McCormick
Andrew Leitner, MD, of City of Hope, discusses the challenges of integrating supportive care into cancer treatment and proposes solutions to improve access for patients from underserved communities.
Closing Gaps in Value-Based Cancer Care
September 25th 2024

Closing Gaps in Value-Based Cancer Care

Brooke McCormick
Linda Bosserman, MD, PhD, FASCO, FACP, of City of Hope, emphasizes the need for a sustainable health care system that balances cost with care so patients can achieve the best survival and quality of life after a cancer diagnosis.
Ted Okon, MBA
September 24th 2024

New FTC Lawsuit Against PBMs Has Broad Implications for Pharmaceuticals, Ted Okon Says

Julia Bonavitacola Skylar Jeremias
Ted Okon, MBA, executive director of the Community Oncology Alliance, spoke with The American Journal of Managed Care® about how the Federal Trade Commission's (FTC) lawsuit against pharmacy benefit managers (PBMs) could affect the future of pharmaceuticals and oncology.
dr andrew leitner
September 24th 2024

Spotlighting the Critical Role of Supportive Care in Cancer Treatment

Brooke McCormick
Andrew Leitner, MD, City of Hope, highlights the essential role of supportive care in improving the quality of life of patients with cancer undergoing treatment.
Chemotharapy graphic-tashatuvango-stock.adobe.com.jpeg
September 23rd 2024

Higher Risk of Heart Events in Older Cancer Survivors Linked to Chemotherapy

Pearl Steinzor
New research highlights increased stroke, heart attack, and heart failure risks in cancer survivors, especially those treated with chemotherapy.
Glenn Balasky during a video interview
September 22nd 2024

AI in Cancer Care Can Be Powerful, but There Will Be Learning Curves, Says Glenn Balasky

Alexandra Gerlach Laura Joszt, MA
Demonstration projects to show accurate use of artificial intelligence (AI) in cancer care are important to prevent a loss of credibility in the technology, explained Glenn Balasky, executive director, Rocky Mountain Cancer Centers.
dr joseph alvarnas
September 22nd 2024

Precision, Personalization, and Equity: Key Trends Shaping the Future of Cancer Care

Brooke McCormick
Joseph Alvarnas, MD, of City of Hope, discusses how he envisions the future of cancer care over the next decade.
dr joseph alvarnas
September 20th 2024

IVBM Chair Summarizes Key Takeaways on Value-Based Oncology Care

Brooke McCormick
Joseph Alvarnas, MD, of City of Hope, recaps yesterday's Institute for Value-Based Medicine® (IVBM) event on value-based oncology care, emphasizing patient-centered approaches and how attendees can apply these insights in their daily practice.
AJMC
September 20th 2024

Systemic Treatments for Advanced Prostate Cancer: Relationship Between Health Insurance Plan and Treatment Costs

Deborah R. Kaye, MD, MS Hui-Jie Lee, PhD Alexander Gordee, MA Daniel J. George, MD Charles D. Scales Jr, MD, MSHS Peter A. Ubel, MD M. Kate Bundorf, PhD, MBA, MPH
The authors examine how insurer and patient out-of-pocket payments for advanced prostate cancer differ by drug and health plan type and describe the relationship between these payments and utilization.
Incorporating Discussions of Cannabis Use Into Oncology Care Visits
September 15th 2024

Incorporating Discussions of Cannabis Use Into Oncology Care Visits

Laura Joszt, MA
The legalization of recreational marijuana in Minnesota has created daily conversations about how to incorporate the use of cannabis into treatment plans for patients with cancer, explained Marie Parish, PharmD, BCOP, of Mayo Clinic.
Cancer health care concept-wladimir1804-stock.adobe.com
September 13th 2024

From Policy to Practice: NCCN Summit Explores Equity in the Cancer Workforce

Giuliana Grossi
The National Comprehensive Cancer Network Policy Summit emphasized the importance of integrating diversity, equity, and inclusion into the oncology workforce to improve cancer care outcomes and address disparities while navigating legal and societal challenges.
Addressing Disparities in Long-Term Survivorship and Quality of Life for Young Patients With Breast Cancer
September 13th 2024

Addressing Disparities in Long-Term Survivorship and Quality of Life for Young Patients With Breast Cancer

Alana Hippensteele
Disparities continue in younger patients, raising the need for novel interventions to mitigate challenges associated with younger age at diagnosis.
Dax Kurbegov, MD, senior vice president, Sarah Cannon Cancer Network
September 12th 2024

Dr Dax Kurbegov on Gaps Between Payers, Health Systems, and Providers in Oncology

Rose McNulty
Dax Kurbegov, MD, senior vice president of Sarah Cannon Cancer Network, discussed divides between payers, health systems, and oncology care providers, as well as the impacts these divides can have on patients.
Brain MRI | Image credit: stockdevil - stock.adobe.com
September 11th 2024

TIM3 Targeted Immunotherapy Shows Promise in Pediatric Brain Cancer

Pearl Steinzor
Breakthrough research identifies TIM3 as a key target in MAPK-activated pediatric gliomas, offering new hope for more effective immunotherapy treatments.
AJMC
September 6th 2024

The Feasibility and Equity of Text Messaging to Determine Patient Eligibility for Lung Cancer Screening

Ilona Fridman, PhD Lisa Carter-Bawa, PhD, MPH, APRN, ANP-C Christine M. Neslund-Dudas, PhD Jennifer Elston Lafata, PhD
Text messaging shows promise for assessing smoking status and identifying lung cancer screening eligibility, particularly among middle-aged, educated individuals with medium or high income. However, a multimodal approach is crucial for equitable implementation of such a program.
Doctor and patient with breast cancer. | Image Credit: Pixel-Shot - stock.adobe.com .jpeg
September 3rd 2024

The Connection Between Cancer Treatment Choices and Suicide Mortality

Pearl Steinzor
Patients with cancer who forego surgery have higher suicide incidence than those who undergo treatment, a study finds.
When to Pause Before Recommending Cannabis to Patients With Cancer
September 1st 2024

When to Pause Before Recommending Cannabis to Patients With Cancer

Laura Joszt, MA
Despite lacking some data, there is some information on which patients with cancer shouldn’t be recommended cannabis or certain cannabis products, said Marie Parish, PharmD, BCOP, a gastrointestinal oncology pharmacist with Mayo Clinic.
Matthew Nielsen, MD
August 31st 2024

Using Active Surveillance to Spare Men From Unneeded Prostate Cancer Treatment

Laura Joszt, MA
Advances in technology have made active surveillance in men with prostate cancer possible and prevented treatment for men who don’t need it, said Matthew Nielsen, MD, FACS, chair, Department of Urology, University of North Carolina School of Medicine.
Neal D. Shore, MD
August 28th 2024

Evaluating Which Patients With Prostate Cancer Will Benefit From Triplet Therapy

Laura Joszt, MA
Not all patients will want to take triplet therapy, but those with high-volume prostate cancer who are chemotherapy eligible are usually a good fit, explained Neal D. Shore, MD, FACS.
Value-based care concept | Image credit: momius - stock.adobe.com
August 27th 2024

Thyme Care Strengthens Value-Based Oncology Care With Dr Lalan Wilfong

Pearl Steinzor
Thyme Care welcomes its new senior vice president to lead initiatives in value-based oncology care.
Health care concept on $100 dollar bill | Image credit: ricardoreitmeyer - stock.adobe.com
August 26th 2024

The Role of Community, Structural Factors in Financial Hardship Among Cancer Survivors

Pearl Steinzor
Social vulnerability and economic disadvantages exacerbate financial hardship in cancer survivors, according to one study.
Marie Parish, PharmD, BCOP, screenshot
August 22nd 2024

Using Cannabis as a Bridge for Symptom Management in Cancer

Laura Joszt, MA
Patients with cancer will never completely replace existing pain regimens, but cannabis could be used in conjunction, explained Marie Parish, PharmD, BCOP, a gastrointestinal oncology pharmacist with Mayo Clinic.
Psychologist holding arm of patient in support | Image credit: pressmaster - stock.adobe.com
August 21st 2024

Spouses of Patients With Cancer Face Elevated Suicide Risk, Study Finds

Pearl Steinzor
Spouses of patients with cancer face a significantly higher risk of suicide attempts and suicide death, especially within the first year of diagnosis, according to one study.
FDA approval | Image Credit: cartoon-stock.adobe.com
August 16th 2024

FDA Approves Durvalumab Combination Therapy for Resectable Early-Stage NSCLC

Pearl Steinzor
The newly approved treatment regimen demonstrated a significant reduction in recurrence risk in patients with resectable non–small cell lung cancer (NSCLC).
Andrew Hantel, MD
August 14th 2024

We Need to Lower Barriers to and Burdens of Trial Entry: Dr Andrew Hantel

Kyle Munz
Andrew Hantel, MD, Dana-Farber Cancer Institute, discusses factors contributing to disparities in oncology clinical trial enrollment.
AJMC
August 13th 2024

The Accelerated Approval Program for Oncology Drugs: Celebrating More Than 250,000 Life-Years Gained and Counting

Julie Patterson, PharmD, PhD John Michael O’Brien, PharmD, MPH Jonathan D. Campbell, PhD
This commentary explores how 2 recently published studies evaluating the clinical benefit of the FDA’s accelerated approval program for oncology drugs came to different conclusions.
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