Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com
C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com
Novel Biomarkers May Inform Prognosis in SCLC

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com
Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center
ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com
5 Key FDA Approval Dates Mark a Milestone-Filled May

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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Segment 5 - An Ideal Patient Portal
November 3rd 2016

Segment 5 - An Ideal Patient Portal

Is there anything like an ideal patient portal that can cater to a broad range of patients? According to Rebekkah Schear, MIA, what patient portals lack is a holistic approach toward the patient.
Segment 4 - Overcoming Barriers With Data Exchange
November 3rd 2016

Segment 4 - Overcoming Barriers With Data Exchange

How can we create more standardized health information platforms that can easily exchange patient information?
Segment 3 - Challenges With Oncology Care Navigation
November 3rd 2016

Segment 3 - Challenges With Oncology Care Navigation

Cancer is a complex disease to treat an patients can be overwhelmed by the number of care providers that they have to consult with. In this scenario, care navigators can provide significant support to patients and their family members.
Segment 2 - Documenting the Treatment Plan
November 3rd 2016

Segment 2 - Documenting the Treatment Plan

Panelists discuss the need for documenting a treatment plan early in patient care.
Segment 1 - Patient-Centered Care and Shared Decisions in Oncology
November 3rd 2016

Segment 1 - Patient-Centered Care and Shared Decisions in Oncology

Joseph Alvarnas, MD, editor-in-chief of Evidence-Based-OncologyTM spoke with Rebekkah Schear, MIA, and Michael Kolodziej, MD, to discuss the progress and challenges in oncology care.
Dr Andrew L. Pecora Outlines Issues Oncologists Have With Value Frameworks
November 2nd 2016

Dr Andrew L. Pecora Outlines Issues Oncologists Have With Value Frameworks

Oncologists are aware of the various value frameworks that have popped up recently, but they are still in the first phase and many oncologists have issues with the frameworks, said Andrew L. Pecora, MD, FACP, CPE, chief innovation officer professor and vice president of cancer services at the John Theurer Cancer Center.
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November 1st 2016

Chemo Brain May Have a Solution: Insight

Surabhi Dangi-Garimella, PhD
A new study suggests that a Web-based intervention could improve a cancer survivor’s cognitive function post treatment.
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November 1st 2016

CVS Reverses Decision on Physician Dispensing of Oncology Drugs

Surabhi Dangi-Garimella, PhD
CVS Health has reversed its decision on physician dispensing of specialty drugs, originally meant to be implemented by January 1, 2017.
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October 31st 2016

Phase I Study Indicates Pembrolizumab an Option in Heavily Pretreated Hodgkin Lymphoma

AJMC Staff
A small, early-stage study in patients with Hodgkin lymphoma who had failed multiple treatments or relapsed after stem cell transplant indicates that pembrolizumab could be a favorable treatment option in these patients.
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October 31st 2016

Researchers Aren't Taking Advantage of Clinical Trial Data-Sharing Project

Surabhi Dangi-Garimella, PhD
A perspective piece, published by researchers from Rutgers University, laments the lack of interest shown by researchers in a clinical trial data-sharing project launched in January 2014.
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October 28th 2016

Study Results Could Help Strengthen Response to Checkpoint Inhibitors

Surabhi Dangi-Garimella, PhD
An animal study conducted at the Perelman School of Medicine, University of Pennsylvania, has identified a mechanism to strengthen the immune response of T cells in cancer patients who are treated with checkpoint inhibitors.
This Week in Managed Care: October 28, 2016
October 28th 2016

This Week in Managed Care: October 28, 2016

This week, the top stories in managed care included an announcement that premiums on Obamacare plans are set to increase by 25% on average, a discussion of Medicare Advantage growth at America's Health Insurance Plans' National Conference on Medicare, and recommendations for success with the Oncology Care Model.
Dr Scott Gottlieb: PCOC Is a Good Place to Meet Thought Leaders in Oncology
October 28th 2016

Dr Scott Gottlieb: PCOC Is a Good Place to Meet Thought Leaders in Oncology

Patient-Centered Oncology Care offers attendees the opportunity to meet and interact with high-level people from various segments of the healthcare industry, explained Scott Gottlieb, MD, resident fellow at the American Enterprise Institute.
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October 27th 2016

Age Is Not a Risk Factor for Post-Mastectomy Reconstructive Surgery

Surabhi Dangi-Garimella, PhD
Long-term follow-up of women who underwent mastectomy and breast reconstruction subsequent to a breast cancer diagnosis found that the success of the procedure and associated complications were not influenced by the woman’s age.
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October 26th 2016

Will a Payer—Provider Collaboration Guarantee OCM Success?

Surabhi Dangi-Garimella, PhD
At the Payer Exchange Summit V, sponsored by the Community Oncology Alliance, oncologists and payers came together to discuss the role of collaboration and data sharing for the successful implementation of the Oncology Care Model.
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October 26th 2016

Employers Express Their Concerns With Cancer Care at the COA Summit

Surabhi Dangi-Garimella, PhD
At the Payer Exchange Summit V, sponsored by the Community Oncology Alliance (COA), 2 employer groups and a provider participated on a panel to provide practical insight into the extraordinary challenges and decisions faced by employers and employees with a cancer diagnosis.
Dr Karen van Caulil on Value-Based Oncology Care Models for Large Employers
October 26th 2016

Dr Karen van Caulil on Value-Based Oncology Care Models for Large Employers

When transitioning towards value-based oncology, large employers should look to value-based models that have worked for other conditions, said Karen van Caulil, PhD, president and CEO of the Florida Health Care Coalition. These successful payment models include patient-centered medical homes, bundled payments, and accountable care organizations.
Barry Russo Discusses Challenges of Juggling OCM and MIPS
October 26th 2016

Barry Russo Discusses Challenges of Juggling OCM and MIPS

Many oncology practices are still trying to understand the new Oncology Care Model (OCM) structure and focus on data reporting as they simultaneously prepare to adapt to the Merit-based Incentive Payment System (MIPS), said Barry Russo, CEO of The Center for Cancer & Blood Disorders.
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October 25th 2016

Pembrolizumab Is FDA-Approved as First-Line for PD-L1—Positive NSCLC

AJMC Staff
Patients newly diagnosed with non—small cell lung cancer (NSCLC) that expresses the programmed death ligand-1 (PD-L1) protein now have a new treatment option: pembrolizumab (Keytruda).
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October 25th 2016

Strategies for OCM Implementation at the COA Payer Summit

Surabhi Dangi-Garimella, PhD
What are some of the challenges that clinical practices will face as they implement the Medicare Oncology Care Model (OCM)? What are some of the strategies that have worked for practices using similar payment models? These were some of the questions discussed at the Payer Exchange Summit V.
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October 25th 2016

How Can Practices Seek Success With Oncology Payment Reform?

Surabhi Dangi-Garimella, PhD
At the Payer Exchange Summit V, sponsored by the Community Oncology Alliance, held October 24-25, 2016, in Tyson’s Corner, Virginia, Bruce Gould, MD, presented an overview of how cancer care has improved over the years, what the challenges are, and how practices can adapt to payment reform.
Dr Marianne Fazen on Why Cancer Is a Major Concern for Employers
October 25th 2016

Dr Marianne Fazen on Why Cancer Is a Major Concern for Employers

Employers face tough decisions about rising costs, high-quality care, coordination of benefits, and workplace accommodations when employees are diagnosed with cancer, but they will always want to support those employees as best they can, according to Marianne Fazen, PhD, president and CEO of the Texas Business Group on Health.
Dr Kashyap Patel Discusses Challenges of OCM Implementation
October 25th 2016

Dr Kashyap Patel Discusses Challenges of OCM Implementation

Adopting the Oncology Care Model (OCM) is a challenging task for oncology practices that have to redesign their practices, but the shift from volume-based to value-based care is the way of the future, said Kashyap Patel, MD, of the Carolina Blood & Cancer Center.
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October 24th 2016

Prior Authorization Pilot Reduced Health Plan's Cancer Drug Costs by 20%

Surabhi Dangi-Garimella, PhD
Including a real-time decision support tool in the prior authorization process significantly reduced the cost of therapy for UnitedHealthcare, while complying with nationally accepted guidelines established by the National Comprehensive Cancer Network.
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October 24th 2016

Geographical Disparities Exist With US Smoking Prevention Policies

Surabhi Dangi-Garimella, PhD
Analysis by researchers from the American Cancer Society has found that US southern states rank at the top when it comes to death from cigarette smoking.
This Week in Managed Care: October 21, 2016
October 21st 2016

This Week in Managed Care: October 21, 2016

The top stories in managed care included Vice President Joe Biden's released his report on the Cancer Moonshot initiative, complaints were filed against 7 insurers for discriminating against people with HIV, and Pfizer announced it plans to launch its Remicade biosimilar in November.
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October 21st 2016

5 Approaches for Improved Collaboration in Oncology Care

Surabhi Dangi-Garimella, PhD
Communication gaps complicate healthcare and can devastate the prognosis of a patient undergoing cancer treatment. Here are a few ways to overcome inconsistencies with cancer care delivery
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October 20th 2016

Obesity: A Growing Burden for Cancer Survivors

Priyam Vora
Patients with a history of cancer were more likely to suffer from obesity than the general population, according to new research studying the incidence of obesity in cancer survivors.
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October 20th 2016

NCHS Report: Rising Survivorship in Pediatric Cancers, Brain Cancer Leading Cause of Death

Surabhi Dangi-Garimella, PhD
Brain cancer has replaced leukemia as the leading cause of cancer-related death in children and adolescents diagnosed with cancer.
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October 20th 2016

Underutilization of Follow-up Imaging in Breast Cancer Survivors a Cause for Concern

Surabhi Dangi-Garimella, PhD
A study presented at the 2016 Annual Clinical Congress of the American College of Surgeons claims that one-third of women diagnosed with breast cancer do not receive their follow-up exam.
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