Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com

C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

By Jared Kaltwasser

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com

Novel Biomarkers May Inform Prognosis in SCLC

By AJMC Contributor

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

By Rose McNulty

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center

ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

By Mary Caffrey

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com

5 Key FDA Approval Dates Mark a Milestone-Filled May

By Brooke McCormick

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

December 30th 2015

Can Indication-Based Pricing Be a Reality?

December 30th 2015

Oral Parity Laws and Patient Cost Sharing

December 30th 2015

Drug Prices and Patient Burden in Oncology

December 30th 2015

Bundled Payments in Oncology: What Do Payers Think?

December 30th 2015

Implications of Bundled Payments in Oncology

December 30th 2015

What Are the Constructs of Value-Based Care?

December 30th 2015

Can Academic Innovation in LDTs Be Halted?

December 30th 2015

LDTs and the Political Wheelhouse

December 30th 2015

Justifying the Need for FDA Regulation of LDTs

December 30th 2015

Payer and Consumer Response to FDA Regulation of LDTs

December 30th 2015

What Are LDTs and How Are They Regulated?

December 30th 2015

Introduction

December 30th 2015

Physicians Discover Palbociclib Effective in Cancers Beyond Those of the Breast

Surabhi Dangi-Garimella, PhD

A literature review by researchers at the Abramson Cancer Center has identified a potential use of the cell cycle inhibitor palbociclib in a variety of cancers.

December 30th 2015

Most-Read Articles From AJMC's Conference Coverage in 2015

Surabhi Dangi-Garimella, PhD

Studies that provided updates on new drug trials, sessions on value-based care, and the cost of healthcare, were most popular among readers of The American Journal of Managed Care.

December 29th 2015

Using Technology to Bring Palliative Care to the Patient's Doorstep

Surabhi Dangi-Garimella, PhD

After having launched a palliative care program in 2014, Cambia Health Solutions is now looking for ways to improve patient access to these tools that can improve a patient's quality of life.

December 29th 2015

Cost, Value of Cancer Drugs Take Center Stage in Current Issue of AJMC's Evidence-Based Oncology

One of the biggest stories of 2015 has been the cost of cancer drugs, which create vexing questions for payers and policymakers, as well as doctors and families. The tough choices being made today are the theme of the latest special issue of Evidence-Based Oncology, a publication of The American Journal of Managed Care.

December 28th 2015

Improving Cancer Trial Participation via Web-Based Interventions

Surabhi Dangi-Garimella, PhD

Patient awareness and educational support can improve their attitude as well as prepare them to make better informed decisions on clinical trial participation, a new study has found.

December 28th 2015

Report: Shkreli Arrest Prompts Cancer Center to Stop Trial

Mary K. Caffrey

Moffitt Cancer Center said there's nothing wrong with the drug, but a spokesman said the trial is halted for now pending the outcome of the investigation.

December 28th 2015

Cancer's Toll Beyond the Disease: Medical Costs and Productivity

Surabhi Dangi-Garimella, PhD

A new study published by the American Cancer Society found that younger colorectal cancer survivors end up spending over $8500 annually in medical expenses and they also experience significantly greater loss of productivity compared with individuals without cancer.

December 26th 2015

This Week in Managed Care: December 26, 2015

This week The American Journal of Managed Care offers a special episode of highlights from the American Society of Hematology's annual meeting, including sessions on newly approved treatments, how the move to pay-for-performance affects hematologists, and the increasing role of patient-reported outcomes.

December 25th 2015

Most-Viewed Videos from AJMC for the Year 2015

Surabhi Dangi-Garimella, PhD

Top 10 videos from The American Journal of Managed Care's Summit and Insight programs.

December 23rd 2015

Rivaroxaban Safe and Effective in Cancer Patients With Thrombosis

Laura Joszt, MA

Although rivaroxaban was approved by the FDA in 2012, there has remained a knowledge gap about how it works with cancer patients. A recent study found that the therapy is safe and effective when used among patients with cancer.

December 22nd 2015

OB-GYN Groups Say Insurers' Genetic Testing Rules Limit Access to Care

Mary K. Caffrey

The statement from the obstetricians and gynecologists said that there aren't enough certified genetic counselors to meet demand. In a statement, the groups said this will limit access to care if patients must wait for assistance before ordering tests.

December 22nd 2015

Top 10 Articles from Evidence-Based Oncology for the Year 2015

Surabhi Dangi-Garimella, PhD

The most read articles in The American Journal of Managed Care's Evidence-Based Oncology ranged from personal narratives to healthcare policy issues that impact the broader population.

December 19th 2015

This Week in Managed Care: December 19, 2015

This week in managed care, Martin Shkreli, CEO of Turing Pharmaceuticals was arrested on charges of fraud; new research find that drug costs continue to take up a larger share of healthcare spending; and 3 healthcare experts take a look at how to fix the 340B drug pricing program.

December 18th 2015

Merck's Pembrolizumab Receives Approval for Expanded Indications

AJMC Staff

Pembrolizumab has been approved as first-line treatment for patients with unresectable or metastatic melanoma.

December 18th 2015

What We're Reading: Taxpayers Spending Millions on Expensive Generic Drugs

AJMC Staff

What we're reading, December 18, 2015: HHS report finds generic drug prices rising faster than inflation; UnitedHealthcare's real-time drug approval tool; and government overcharged by private Medicare Advantage plans.

December 18th 2015

Progress Toward Healthy People 2020: CDC Report Claims Reduction in Cancer Incidence

Surabhi Dangi-Garimella, PhD

Results of an analysis of 2012 cancer incidence and survival from various cancer registries, published in CDC's Morbidity and Mortality Weekly Report, indicates reduced incidence of overall cancer across the United States.

December 18th 2015

FDA Seeks Nationwide Ban on Letting Minors Use Tanning Beds

Mary K. Caffrey

Eleven states already ban minors from using tanning beds, and most states have other restrictions such as requiring a parent's permission.

December 17th 2015

Report Provides an Update on the 340B Drug Pricing Program

Surabhi Dangi-Garimella, PhD

A new report by the Berkeley Research Group provides numbers on Medicare Part B spending by 340B entities, especially for oncology drugs.

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