Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com
C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com
Novel Biomarkers May Inform Prognosis in SCLC

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com
Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center
ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com
5 Key FDA Approval Dates Mark a Milestone-Filled May

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

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October 15th 2015

Health Plan Recommends More Interventions for Tangible Results With Choosing Wisely

Surabhi Dangi-Garimella, PhD
The analysis by Anthem Inc, has identified a need for more widespread implementation of these interventions aimed at reducing healthcare utilization.
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October 15th 2015

Study Confirms: Calcium and Vitamin D Cannot Prevent Colon Cancer

Surabhi Dangi-Garimella, PhD
The study, published in the New England Journal of Medicine failed to confirm epidemiologic and preclinical data that vitamin D and calcium can reduce the risk of colorectal neoplasia.
Mary Lou Smith on Ensuring Patients Feel Cared For
October 15th 2015

Mary Lou Smith on Ensuring Patients Feel Cared For

One way to make all patients with cancer, regardless of socioeconomic status, feel like they're on the same level when receiving treatment is to ensure they know they're being taken care of, said Mary Lou Smith, MBA, co-founder of the Research Advocacy Network.
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October 15th 2015

Organization That Addresses "Financial Toxicity" in Young Cancer Survivors Featured in Evidence-Based Oncology

The Samfund, the first and largest group created to help young adults address the costs of cancer, is featured in the current issue of Evidence-Based Oncology, a publication of The American Journal of Managed Care. Samfund officers Samantha Watson, MBA, and Michelle S. Landwehr, MPH, address the challenges of "financial toxicity" for young adult survivors.
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October 15th 2015

Patient Advocacy Meets Payer in the World of Personalized Medicine

Surabhi Dangi-Garimella, PhD
A panel discussion during the 2nd PMC/BIO Solutions Summit identified barriers and discussed the path forward to improve clinical integration of precision medicine.
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October 14th 2015

Financial Toxicity and the Young Adult Cancer Survivor

Samantha Watson, MBA Michelle S. Landwehr, MPH
The financial aftereffects of cancer have a tremendous impact on young adults as they move forward with their lives after treatment.
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October 14th 2015

FDA Updates in Oncology

Surabhi Dangi-Garimella, PhD
Updates on FDA approvals and extended indications for oncology drugs.
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October 14th 2015

Using a Gene Expression Assay to Predict Response to NAC in Breast Cancer

Surabhi Dangi-Garimella, PhD
Evaluation of Prosigna's risk of relapse score as a predictor of response to multiagent neoadjuvant chemotherapy in HR+/HER2 breast cancer patients.
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October 14th 2015

Managed Care Updates in Oncology

Surabhi Dangi-Garimella, PhD Mary Caffrey
An update on recent progress in oncology managed care.
Dr Peter Bach on the Benefit of Bringing Stakeholders Together at PCOC15
October 14th 2015

Dr Peter Bach on the Benefit of Bringing Stakeholders Together at PCOC15

The Patient-Centered Oncology Care meeting provides a great opportunity for stakeholders from across healthcare to get together, and when that happens very good things can come from it, according to Peter Bach, MD, MAPP, director of Memorial Sloan Kettering Cancer Center's Center for Health Policy and Outcomes.
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October 14th 2015

One Winner Looks Likely in Louisiana Governor's Race: Medicaid Expansion

Mary K. Caffrey
Earlier this year, the legislature laid the groundwork for Medicaid expansion to occur in 2016.
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October 13th 2015

How Do You Improve Geriatric Participation in Cancer Trials?

Surabhi Dangi-Garimella, PhD
The American Society of Clinical Oncology has issued a statement asking for an improved evidence base for treating older adults with cancer.
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October 13th 2015

Example of A Clinical Care Gap: Oncologists and Genetic Counselors

Surabhi Dangi-Garimella, PhD
A new study, published in JAMA Oncology has identified a widespread gap in counseling services for patients who undergo BRCA testing.
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October 12th 2015

Cancer Can Cause Heart Failure

Surabhi Dangi-Garimella, PhD
A study presented at the European Society of Cardiology meeting has found that cancer increases cardiac stress, which is further accentuated by chemotherapy.
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October 12th 2015

10 Cancer Researchers Can Receive $7.5 Million in Funds

AJMC Staff
Stand Up 2 Cancer, in collaboration with the American Association for Clinical Research, will be funding innovative research grants with a potential to further translational cancer research.
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October 12th 2015

The Need to Raise Awareness for Young Adult Cancer Care

Surabhi Dangi-Garimella, PhD
Adolescent and young adult cancer patients face multiple barriers to ensuring adequate care: from unsure providers to financial constraints. Improved care coordination and recognition of the needs of this population can lead to much improved outcomes.
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October 12th 2015

Pediatric Oncologist A Firm Believer in the Potential of Next Generation Sequencing

Surabhi Dangi-Garimella, PhD
Evidence-Based Oncology spoke with Rajen Mody, MBBS, from the University of Michigan Health System, about his experiences treating young cancer patients, the survivorship program offered by the University of Michigan, and next generation sequencing.
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October 12th 2015

Sticking Up for the 340B Program

Changes in the healthcare marketplace are steadily pushing changes for physicians and specialty practices of all kinds. Blaming the 340B drug discount program is both misleading and unproductive.
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October 12th 2015

Now a New Companion Diagnostic for Nivolumab in Non-Squamous NSCLC

Surabhi Dangi-Garimella, PhD
The new test, developed by Dako, will provide information on the survival benefit of patients with non-squamous NSCLC treated with nivolumab.
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October 10th 2015

This Week in Managed Care: October 10, 2015

Top managed care stories this week include how much waiting to see the doctor costs patients, Express Scripts announced it will cover both PCSK9 inhibitors, and HHS proposed simplifying rules for providers using electronic health record.
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October 9th 2015

Can Cancer Survival Outcomes Help You Choose Your Site of Care?

Surabhi Dangi-Garimella, PhD
A new study published in JAMA Oncology has identified disparate survival outcomes across sites of care.
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October 9th 2015

Nivolumab Receives Extended Approval for Advanced Lung Cancer

AJMC Staff
The PD-1 inhibitor antibody was approved by the FDA for use in patients who have progressed on platinum-based treatment.
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October 9th 2015

NICE Believes Pembrolizumab Is Worth It in Treatment-Naïve Melanoma Patients

Surabhi Dangi-Garimella, PhD
With the final guidance expected in November, UK will follow Europe in the use of pembrolizumab in treating advanced melanoma patients refractory to previous treatment as well as those who have not been previously treated.
Dr Joseph Alvarnas Considers Survivorship and Long-Term Effects of Cancer Therapy
October 9th 2015

Dr Joseph Alvarnas Considers Survivorship and Long-Term Effects of Cancer Therapy

With new treatments helping patients with cancer to live longer, healthcare providers now have new issues of long-term survivorship to consider, said Joseph Alvarnas, MD, the editor-in-chief of Evidence-Based Oncology.
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October 8th 2015

Bridging the Care Gap Between Pediatric and Young Adult Cancer

Laurel Barosh, MPH Terry Church, MA, MS Deborah Morgan, MSN, RN, OCN Megan Bianchetti, MSW James Hu, MD, FACP Debu Tripathy, MD Stuart E. Siegel, MD
Through a multi-site, multidisciplinary approach, AYA@USC addresses the unique needs of young adult cancer patients, improving outcomes and bridging the care gap in this population.
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October 8th 2015

Treatment of Acute Lymphoblastic Leukemia in Adolescents and Young Adults

Joseph Rosenthal, MD
Adolescent and young adults (AYA) constitute a distinct population amongst patients with cancer. Historically, AYA patients with ALL treated along pediatric-inspired protocols had better outcomes compared to those treated on standard "adult type" regimens.
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October 8th 2015

Picking Up the Pieces - Thoughts on Cancer by a 25-Year-Old 8-Time Cancer Survivor

Woodrow Roseland
My role as a patient was simple-accept the suffering I had to endure. But it becomes hard to find the line between when to suffer and when to question.
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October 8th 2015

Pioneer in Cancer Immunotherapy Receives Federal Award

AJMC Staff
Steven Rosenberg, MD, chief of surgery at NCI's Center for Cancer Research, has been awarded the 2015 Samuel J. Heyman Service to America Medal, or Sammie for his contributions to the field of immune-based cancer treatments.
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October 8th 2015

Successful Ovarian Tissue Transplants Bring Promise of Fertility in Cancer Survivors

Surabhi Dangi-Garimella, PhD
A retrospective follow-up in women who had received grafts of cryopreserved ovarian tissue discovered a 30% success rate in bearing a child.
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October 7th 2015

Access to Palliative Care Remains Inadequate, Report Finds

Laura Joszt, MA
Millions of Americans with serious illness, such as cancer, heart disease, kidney disease, and dementia, continue to have inadequate access to palliative care, according to the 2015 State-by-State Report Card from the Center to Advance Palliative Care.
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