Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com

C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

By Jared Kaltwasser

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com

Novel Biomarkers May Inform Prognosis in SCLC

By AJMC Contributor

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com

Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

By Rose McNulty

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center

ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

By Mary Caffrey

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com

5 Key FDA Approval Dates Mark a Milestone-Filled May

By Brooke McCormick

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

October 7th 2015

Smaller Tumors Mean Better Breast Cancer Survival: Dutch Study

Surabhi Dangi-Garimella, PhD

Tumors caught early have a lower probability of advancing to the lymph nodes and improve patient outcomes, the BMJ study found.

October 7th 2015

Avelumab Receives Fast-Track for Merkel Cell Carcinoma

AJMC Staff

The PD-L1 inhibitor was granted orphan drug status just last month.

October 7th 2015

The Price Is Right? Not for Mammograms

Surabhi Dangi-Garimella, PhD

Price transparency continues to plague healthcare, as this new report from Castlight Health suggests.

October 6th 2015

California's Governor Signs Right-to-Die Law

Mary K. Caffrey

Despite safeguards, opponents of the California law say it will invite abuse of the poor who suffer chronic conditions and face steep medical costs.

October 6th 2015

HIV Survivors Need Cancer Prevention

Surabhi Dangi-Garimella, PhD

As HIV-infected adults live longer, they are increasingly susceptible to specific cancer types. This calls for targeted cancer prevention efforts in this population.

October 6th 2015

The Challenge of Palliative Care for Adolescents and Young Adults

Clarke P. Anderson, MD

End-of-life care for adolescents and young adults requires an approach that addresses the unique developmental and spiritual issues seen in that population.

October 6th 2015

LIVESTRONG Fertility Training: Addressing the Needs of AYA Cancer Survivors

Bree Hemingway, MPH Aditi Narayan, MSW Sarah Avery, PhD

A discussion on the challenges of implementing standards for addressing fertility risks associated with cancer and its treatment and describes an interactive training for healthcare providers to help them overcome challenges to implementation.

October 6th 2015

Tips for Caring for Patients Who Have Been Treated for Childhood Cancer

Lisa Diller, MD

Suggestions on how to approach a childhood cancer survivor in your practice, several useful resources, and information on what referrals and tests may be indicated.

October 6th 2015

Patient Assistance Programs Ensure Affordable and Quality Cancer Care

Surabhi Dangi-Garimella, PhD

A multistakeholder approach to patient assistance programs was the topic of discussion at ACCC's first annual ICLIO meeting in Philadelphia.

October 5th 2015

Weight-Loss Surgery Can Prevent Cancer, Now Let's Pay for It

Surabhi Dangi-Garimella, PhD

The evidence of weight-loss improving overall well-being and predisposition to chronic as well as acute conditions is mounting. We now need coverage policies that can help patients take advantage of weight loss procedures.

October 5th 2015

Dr Mark Kris Explains Changes Emerging From Genetic Testing

The use of genetic testing has led to a radical change within certain specialties and hospital departments. And although doctors are being asked to do more, they do it gladly because the work leads to better treatment decisions for patients, said Mark G. Kris, MD, William and Joy Ruane chair in thoracic oncology at Memorial Sloan Kettering Cancer Center.

October 5th 2015

Who Pays for Immuno-Oncology?

Surabhi Dangi-Garimella, PhD

Reimbursement remains a primary concern with the new immuno-oncology agents. Who pays and how do you ensure payment was fervently discussed by oncologists at the recent ICLIO meeting hosted by the Association of Community Cancer Centers.

October 2nd 2015

Access to Palliative Care Remains an Issue in US Hospitals

Surabhi Dangi-Garimella, PhD

A study reports that despite the steady growth in hospital-based palliative care programs, access is sketchy and is driven by geographic location and hospital ownership.

October 1st 2015

Cancer Survivor Clinics Can Reduce ED Utilization, Study Shows

Surabhi Dangi-Garimella, PhD

A government-funded network of specialized survivor clinics in Ontario, Canada, significantly decreased emergency department visits among adult survivors of childhood cancer.

October 1st 2015

WISDOM Study Aims to Personalize Breast Cancer Screening

AJMC Staff

The study plans to evaluate the impact of a personalized approach to breast cancer screening over an annual mammogram.

October 1st 2015

Opdivo-Yervoy Combination Approved for Metastatic Melanoma Harboring Wild-Type BRAF

Surabhi Dangi-Garimella, PhD

This approval marks the first-ever for 2 immuno-oncology agents in cancer treatment.

September 30th 2015

A Breast Cancer Risk Assessment Tool That Includes Breast Density Measures

Surabhi Dangi-Garimella, PhD

The result of a multicollaborative effort, the study published in the Journal of Clinical Oncology found that incorporating breast density information in the risk calculator could accurately estimate women's risk for the disease.

September 30th 2015

Reply to "Transforming Oncology Care": Advancing Value, Accessing Innovation

Rebecca Paradis, MPA

Patient access to innovation may be at risk as new payment models emerge in oncology.

September 30th 2015

Public Strongly Favors Medicare Funding for End-of-Life Talks, Poll Finds

Mary K. Caffrey

The findings come as CMS is poised to finalize a rule to pay doctors to counsel patients about end-of-life treatment options.

September 30th 2015

Conflict of Interest Rampant in Academic-Industry Partnerships

Surabhi Dangi-Garimella, PhD

A study published in BMJ measured the prevalence, annual compensation, and beneficial stock ownership of directors from publicly traded healthcare companies who had academic affiliations.

September 29th 2015

ECC Data Recommends Fewer but Stronger Doses of Radiation for Prostate Tumors

AJMC Staff

The CHHiP trial found fewer high-dose radiotherapy was as effective as more number of low-dose radiotherapy in men with prostate cancer.

September 29th 2015

CAD Increases Cost and May Even Miss Detecting Breast Cancers, Says BCSC Study

Surabhi Dangi-Garimella, PhD

An NCI-funded Breast Cancer Surveillance Consortium study has found that computer-aided detection and interpretation of mammograms does not add any value to breast cancer screening.

September 29th 2015

The Patient Will See You Now: Part 1

Debra Madden

My visit to the gynecologist's office following treatment for breast cancer and a subsequent reconstructive surgery was a rude awakening.

September 28th 2015

Results of Gene Panel Test Can Determine Need for Chemotherapy in Breast Cancer

Surabhi Dangi-Garimella, PhD

A prospective study that enrolled more than 10,000 women with hormone-receptor—positive, HER2-negative breast cancer has found that their response to a 21-gene test can identify patients who can avoid chemotherapy.

September 28th 2015

Dr Amy Davidoff Highlights the Benefits of Palliative Care, Discusses Biosimilars

Palliative care should enter into the discussion with patients with cancer as early as possible as it can manage symptoms from therapy or it can provide comfort to patients who cannot afford or choose to forgo therapy, said Amy Davidoff, PhD, MS. Plus, she discusses the impact biosimilars may have on therapy costs.

September 28th 2015

Distinct Molecular Tumor Profile in Younger CRC Patients Recognized

Surabhi Dangi-Garimella, PhD

Data presented at the ongoing European Cancer Congress has identified a different epigenetic profile in the tumors of younger colorectal cancer patients, information that can help improve treatment options in this population.

September 27th 2015

Dr Ira Klein Discusses the Use of Fee-for-Service in Oncology

Although CMS has introduced a strict timeline to move to value-based payments, its new Oncology Care Model is partially relying on fee-for-service, and that's a good thing in the case of oncology, said Ira Klein, MD, MBA, senior director of quality, Strategic Customer Group at The Janssen Pharmaceutical Companies of Johnson & Johnson.

September 26th 2015

This Week in Managed Care: September 26, 2015

Top managed care stories this week include the follow up to the National Academy of Medicine's groundbreaking "To Err Is Human" report, findings on the sharp increase in deductibles, and discussing costs in cancer care.

September 25th 2015

First-Ever Therapeutic HPV Vaccine Promising Against Cervical Cancer

Surabhi Dangi-Garimella, PhD

Developed by Inovio Pharmaceuticals, the vaccine has shown the potential to impact precancerous cervical lesions.

September 25th 2015

Results at ESMO Focus on Companion Diagnostics, Avoiding Overtreatment in Prostate Cancer

AJMC Staff

Posters focus on next-generation sequencing ovarian cancer and identify candidates for treatment with PARP inhibitors.

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