Oncology

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The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com
C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

June 7th 2025

The findings are notable in part because therapies have already been approved to target C5aR1 in other diseases.

The study identified several molecular markers related to SCLC prognosis by integrating somatic mutation profiles, mRNA transcriptome data, and clinical information. | Image credit: vitstudio - stock.adobe.com
Novel Biomarkers May Inform Prognosis in SCLC

June 6th 2025

Structured exercise programs should be a part of the standard of care for colon cancer following adjuvant chemotherapy, authors of the COMMANDS study recommended. | Image credit: Drazen - stock.adobe.com
Structured Exercise Program Improves Outcomes, Quality of Life in Colon Cancer

June 6th 2025

young adult cancer | Image credit: Roswell Park Cancer Center
ASCO Sessions Explore Data and Dynamics of Early-Onset Cancer

June 6th 2025

FDA headquarters | Image Credit: - Tada Images- stock.adobe.com
5 Key FDA Approval Dates Mark a Milestone-Filled May

June 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

Cervical Cancer Screening Rates "Unacceptably Low," Researchers Find
January 10th 2019

Cervical Cancer Screening Rates "Unacceptably Low," Researchers Find

Jaime Rosenberg
Less than two-thirds of women aged 30 to 65 years were up to date with cervical cancer screenings in 2016. The percentage was even lower for women aged 21 to 29, with just over half up to date on screenings.
Cancer Mortality Rate Drops for the 25th Consecutive Year, but Socioeconomic Gap Widens
January 9th 2019

Cancer Mortality Rate Drops for the 25th Consecutive Year, but Socioeconomic Gap Widens

Kelly Davio
For the 25th consecutive year, the cancer mortality rate in the United States has declined, according to The American Cancer Society’s annual report on cancer rates and trends. The overall 27% drop in mortality rate translates into 2.6 million fewer deaths from cancer between the years 1991 and 2016.
What We're Reading: NYC Expands Health Coverage; Hospital Transparency Rule Confusion; Eli Lilly Purchases Loxo Oncology
January 9th 2019

What We're Reading: NYC Expands Health Coverage; Hospital Transparency Rule Confusion; Eli Lilly Purchases Loxo Oncology

AJMC Staff
New York City is expanding health coverage to 600,000 uninsured residents; a transparency rule requiring hospitals to post prices online is confusing patients; and Eli Lilly has purchased Loxo Oncology in what some are calling a massive bet on cancer genetic.
BMS, Celgene Discuss $74 Billion Acquisition During JP Morgan Healthcare Conference
January 8th 2019

BMS, Celgene Discuss $74 Billion Acquisition During JP Morgan Healthcare Conference

Jaime Rosenberg
Bristol-Meyers Squibb (BMS) and Celgene kicked off the 37th Annual JP Morgan Healthcare Conference by discussing their leading drugs, near-term launches, and early pipeline assets.
Dr Brian Koffman: It Is Critical That Patients Educate Themselves and Leverage Their Advantages
January 5th 2019

Dr Brian Koffman: It Is Critical That Patients Educate Themselves and Leverage Their Advantages

As a physician, Brian Koffman, MDCM, DCFP, DABFM, MS Ed, medical director, CLL Society, was able to leverage his medical and scientific knowledge during treatment for his chronic lymphocytic leukemia (CLL), and he encourages other patients to educate themselves on their illnesses in order to receive the best care.
Dr Sibel Blau Explains What the Results of OCM Have Shown
December 31st 2018

Dr Sibel Blau Explains What the Results of OCM Have Shown

Results from the first 2 performance periods of the Oncology Care Model (OCM) highlighted areas where Northwest Medical Specialties was doing well and areas it could improve, said Sibel Blau, MD, medical oncologist at Northwest Medical Specialties, PLLC.
Future of Therapy and Final Thoughts on Myelofibrosis
December 28th 2018

Future of Therapy and Final Thoughts on Myelofibrosis

Symptoms and Patient Progression
December 28th 2018

Symptoms and Patient Progression

Evolution of Myelofibrosis and Efficacy & Toxicity of Therapy
December 28th 2018

Evolution of Myelofibrosis and Efficacy & Toxicity of Therapy

Pacritinib and the Practical Implications
December 28th 2018

Pacritinib and the Practical Implications

Comparison of Ruxolitinib vs Fedratinib and Practical Implications
December 28th 2018

Comparison of Ruxolitinib vs Fedratinib and Practical Implications

Emerging Agents and Review of Fedratinib
December 28th 2018

Emerging Agents and Review of Fedratinib

Long-Term Survival and Adverse Effects With Ruxolitinib
December 28th 2018

Long-Term Survival and Adverse Effects With Ruxolitinib

Mechanism of JAK Inhibitors and a Review of Ruxolitinib
December 28th 2018

Mechanism of JAK Inhibitors and a Review of Ruxolitinib

NCCN Guidelines and Anemia Treatment
December 28th 2018

NCCN Guidelines and Anemia Treatment

Goals of Therapy and Starting Therapy for Myelofibrosis
December 28th 2018

Goals of Therapy and Starting Therapy for Myelofibrosis

Prognosis and Risk Stratification of Myelofibrosis
December 28th 2018

Prognosis and Risk Stratification of Myelofibrosis

Diagnosis of Myelofibrosis
December 28th 2018

Diagnosis of Myelofibrosis

Overview of Myelofibrosis
December 28th 2018

Overview of Myelofibrosis

Chemotherapy for Solid Tumors Associated With Increased Risk of AML, MDS
December 28th 2018

Chemotherapy for Solid Tumors Associated With Increased Risk of AML, MDS

Laura Joszt, MA
Patients who are treated with chemotherapy for their solid tumors have an increased risk of therapy-related myelodysplastic syndrome and acute myeloid leukemia (tMDS/AML) despite advances in chemotherapy regimens, according to a new study in JAMA Oncology.
This Year in Managed Care: 2018 Recap
December 28th 2018

This Year in Managed Care: 2018 Recap

This week, we recapped the top news from 2018 with a look at policy changes, new research, decisions at the polls, and more.
Males With MPN Have More Aggressive Disease Biology, Independent of Other Factors
December 28th 2018

Males With MPN Have More Aggressive Disease Biology, Independent of Other Factors

Jackie Syrop
Males with myeloproliferative neoplasms have worse survival compared with females with MPN, even when adjusted for age at presentation, presenting phenotype, and molecular characteristics.
The Most-Read Articles From Evidence-Based OncologyTM for 2018
December 27th 2018

The Most-Read Articles From Evidence-Based OncologyTM for 2018

Mary Caffrey
From chimeric antigen receptor T-cell therapy to value-based contracting, reimbursement issues dominated reader interest.
Reimbursement With Treatment for Multiple Myeloma
December 27th 2018

Reimbursement With Treatment for Multiple Myeloma

Studies Presented at ASH 2018 and the Outlook for Myeloma
December 27th 2018

Studies Presented at ASH 2018 and the Outlook for Myeloma

MRD Testing and Relapsed/Refractory Multiple Myeloma Treatment Options
December 27th 2018

MRD Testing and Relapsed/Refractory Multiple Myeloma Treatment Options

Transplant Patients' Options, CoMMpass Study, and Doublet Versus Triplet Therapy
December 27th 2018

Transplant Patients' Options, CoMMpass Study, and Doublet Versus Triplet Therapy

Dr Robert Daly Discusses How Clinical Pathways Can Reduce Disparities in Breast Cancer
December 25th 2018

Dr Robert Daly Discusses How Clinical Pathways Can Reduce Disparities in Breast Cancer

There can be great disparities across the country and across races when it comes to cancer care, but clinical pathways can help standardize care so everyone gets the most efficacious treatments, said Robert Daly, MD, MBA, medical oncologist, Memorial Sloan Kettering Cancer Center.
Challenges and Opportunities in the Oncology Care Model
December 23rd 2018

Challenges and Opportunities in the Oncology Care Model

Laura Joszt, MA
The practices that have been participating in CMS’ Oncology Care Model have undergone significant practice transformation in order to be successful in the program. However, even after being in the model for 2 years, there are still remaining opportunities for investment.
Diabetes, Cancer Interviews Among Most-Watched Videos of 2018
December 20th 2018

Diabetes, Cancer Interviews Among Most-Watched Videos of 2018

Laura Joszt, MA
Throughout the year, The American Journal of Managed Care® (AJMC®) offered a number of video programs, including Peer Exchange discussions and interviews, on a range of topics. Here are the most-watched videos published by AJMC® in 2018.
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