Oncology

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The investigators found that patients with SCLC and cachexia were more likely to have problems with treatment. | Image credit: appledesign - stock.adobe.com

Cachexia Worsens Prognosis in Older Patients With Advanced SCLC

July 9th 2025

Older patients with small cell lung cancer and significant weight loss were more likely to experience dose interruptions than patients with cachexia.

Insurance gaps | Image Credit: iQoncept-stock.adobe.com

Insurance Gaps Threaten Cancer Treatment Success

By Maggie L. Shaw

July 7th 2025

Analyzed by birth cohort, the authors found each successive birth cohort had a 7.7% decline in SCLC rates. | Image credit: shidlovski

Decline in SCLC Incidence Expected to Accelerate Through 2050

By Jared Kaltwasser

June 29th 2025

While elevated NLR previously served as a marker of aggressive disease and poor prognosis in SCLC, its prognostic relevance appears to diminish in the context of immunotherapy-based treatment regimens. | Image credit: Crystal light - stock.adobe.com

Challenging the Prognostic Role of NLR in SCLC in the Era of Immunotherapy

By Kimberly Rath, PharmD

June 27th 2025

Gender rights | Image Credit: © Nadzeya-stock.adobe.com

Culture Key to Data Collection of Sexual Orientation and Gender Identity in Cancer Care

By Maggie L. Shaw

June 23rd 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

Continuing Medical Education

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July 13th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology

July 13th 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

More News

February 27th 2015

Studies Highlight Limitations in Emergency Provider Understanding of End-of-Life Care Choices

Emergency care providers vary in their understanding of a type of medical order intended to communicate seriously ill patients' choices for life-sustaining treatments, according to a pair of studies recently published.

February 27th 2015

AJMC Panel Sees Advantages in FDA Regulation of Molecular Diagnostic Tests for Cancer Care

The American Journal of Managed Care convened a discussion of 2 leading clinicians and 2 medical directors for leading payers, all of whom saw some merit in FDA's plans to bring oversight to the diagnostic testing market. The strongest advocate for greater FDA oversight was Daniel F. Hayes, MD, clinical director of the Breast Oncology Program at the University of Michigan, who will be a future president of the American Society of Clinical Oncology.

February 27th 2015

Community Oncology Alliance Announces Launch of Accreditation Pilot for OMH

Ten oncology practices around the nation will initiate their accreditation process this year, which includes an on-site survey bu the Commission on Cancer.

February 26th 2015

NICE Guidelines for Bladder Cancer Can Minimize Care Variance

NICE's first guideline on bladder cancer aims to improve the diagnosis and management of the seventh most common cancer in the UK.

February 26th 2015

Dr Ira Klein Discusses the CMS Oncology Care Model

The goals of the new CMS Oncology Care Model align very nicely with what payers want, according to Ira M. Klein, MD, MBA, FACP, national medical director, clinical thought leadership, office of the chief medical officer, Aetna.

February 26th 2015

Basket Trials Have FDA Support, But Will They Deliver?

Following the introduction of adaptive clinical trials, cancer researchers are now working on another revolutionary model, and they have the FDA's support in this effort. Named basket studies because they group different cancers together based on the driver mutation rather than the tumor of origin, these trials do not use the standard treatment as a control group, but look for a "Yes" or "No" response.

February 25th 2015

Fred Hutch Receives Multimillion Dollar Cancer Research Grant from PCORI

Project to research better way to treat neutropenia is 1 of 5 to get latest funding from Patient-Centered Outcomes Research Institute.

February 25th 2015

NICE Rejects Provenge, Says Treatment is Not Cost-Effective

The governing body for public health in the UK, National Institute for Health and Care Excellence, has refused to fund Provenge citing a high-price for the benefit the tretament provides. This may not be the best news for Valeant Pharmaceuticals which recently bought the regimen from the bankrupt Dendreon Corp.

February 24th 2015

Shared Decision-Making in Cancer Has Several Variables

A study published in the journal Cancer provides insights that may help physicians understand patients' preferences regarding their care, which may be crucial for optimizing patient participation in treatment decisions.

February 24th 2015

Study Results Could Improve Quality of Life in Pediatric ALL

The study, conducted in 2 separate patient cohorts at St. Jude Children's Hospital and the Children's Oncology Group and published in the The Journal of the American Medical Association, found that children with gene variants in the CEP72 gene were more sensitive to vincristine-induced peripheral neuropathy.

February 24th 2015

Study Warns Against Use of VEGF Inhibitors in Advanced Kidney Cancer

Interim analysis of a clinical trial evaluating adjuvant sorafenib, sunitinib or placebo in patients with advanced renal cell carcinoma found the recurrence rates and the disease-free survival were similar between all three treatment regimens.

February 23rd 2015

First HDAC Inhibitor, Developed by Novartis, Approved for Multiple Myeloma

Study results showed participants receiving Farydak with bortezomib and dexamethasone saw a progression-free survival for about 10.6 months,compared to 5.8 months in participants treated with bortezomib and dexamethasone alone.

February 23rd 2015

Coalition of Leading Cancer Centers Aims to Improve Personalized Treatment

"The growth of ORIEN coincides with President Obama's announcement and the recognition that molecularly targeted medicine holds tremendous promise for all disease, particularly cancer," said Michael Caligiuri, MD, director of The Ohio State University Comprehensive Cancer Center and CEO of the James Cancer Hospital and Solove Research Institute.

February 23rd 2015

BMS Deals Set to Boost Company's Oncology Pipeline

The deals, with Flexus and Rigel, will add another molecule to the company's immunotherapy pipeline and also provide access to a TGF-beta receptor inhibitor to be used in combination with Yervoy and Opdivo.

February 23rd 2015

Taiho's NDA for mCRC Under FDA Review

The TAS-102 RECOURSE trial met the primary efficacy endpoint of statistically significant improvement in overall survival versus placebo, and the results of the trial form the basis of the NDA.

February 23rd 2015

Expert Analysis on Managing mCRC

At the 26th International Congress on Anti-Cancer Treatment in Paris, France, earlier this month, oncologists deliberated on the current understanding of metastatic colorectal cancer and the available treatment options. Recent work has shown that there are 4 or 5 different subtypes of the disease, which may call for personalized therapeutic strategies.

February 21st 2015

Managed Care Minute: February 21, 2015

A one-minute look at managed care news during the week of February 16, 2015, including extended open enrollment under the Affordable Care Act and shared decision-making for cancer treatments.

February 20th 2015

Celgene's Revlimid Receives Expanded Approval in Europe Following Similar FDA Approval

After the FDA approved lenalidomide for use in chemotherapy-naive multiple myeloma (MM) patients, the European Commission has followed suit. Revlimid was approved today by EC in MM patients, previously untreated and transplant-ineligible.

February 20th 2015

Study Underscores the Potential of Mobile Health App in Healthcare Decisions

The study, conducted at the Columbia University School of Nursing, found that mobile apps with decision support features resulted in significantly higher diagnosis rates than apps with only bare-bones tools for recording results from a patient exam.

February 20th 2015

UCLA Study Points to Need for Informed Decision-Making in Prostate Cancer

The study evaluated SEER data of over 37,000 prostate cancer patients and found an overwhelming majority of patients (58%) received radiation treatment regardless of overall disease prognosis. The lead study author hopes these findings enlighten the public and allow physicians to make an informed decision when it comes to the best treatment option for men who may or may not benefit from radiation therapy in the long run.

February 20th 2015

FDA Authorizes Sale of First Direct-to-Consumer Genetic Test

Developed by the company 23andMe, the test identifies carriers of a gene mutation that could determine the susceptibility of a person's offspring to Bloom Syndrome.

February 19th 2015

Study Results Challenge CMS Position on Follow-Up Scans in Cancer Patients

Published in the Journal of Nuclear Medicine, the authors show that a fourth and subsequent follow-up PET/CT scan in lung cancer patients was associated with treatment change.

February 19th 2015

Biomarker That Could Predict Survival After CRC Surgery Discovered

Research scientists at the Macquarie University and Concord Repatriation General Hospital in Australia have discovered that expression of the cell surface protein uPAR can predict survival after colorectal cancer (CRC) surgery. The study found that patients expressing uPAR may have undetectable cancer metastasis and dramatically poorer survival.

February 19th 2015

Gardasil 9 Offers Broader Protection, a Global Study Reports

Published in the New England Journal of Medicine, the multinational study found that Gardasil 9, 100% effective against 9 strains of HPV, can prevent the occurrence of 85%-90% of HPV-related cancers.

February 18th 2015

Phyllis Torda Championed Improved Quality Measurement Guidelines in Oncology

On February 16, after living with metastatic breast cancer, Phyllis Torda, 63, vice president of the Quality Solutions Group at the National Committee for Quality Assurance, passed away.

February 18th 2015

Balancing Value, Pathways, and Innovation in Healthcare

As specialty drug costs, formulary wars, and reimbursement models grab headlines everyday, we need to take a step back and visualize how all of this might impact innovation and whether the patient stands to lose in the process.

February 18th 2015

FDA Expands Indication for Revlimid in Multiple Myeloma

Laura Joszt, MA

The combination of Revlimid with dexamethasone, previously approved for treatment in patients with multiple myeloma who received at least 1 prior treatment, has received FDA approval for use in newly diagnosed multiple myeloma patients.

February 18th 2015

Study Identifies Potential Biomarker for Cabazitaxel Response in CRPC

The study published in Clinical Cancer Research elucidated an in vitro mechanism that could explain why cabazitaxel is more effective in some prostate cancer patients. The study also identified a biomarker that could provide precision medicine for a subset of patients.

February 17th 2015

Oncologist to Launch Social Media Campaign Against Cost of Cancer Drugs

Following his collaboration with other research scientists to protest the cost of cancer drugs, Hagop Kantarjian, MD, from the MD Anderson Cancer Center has now turned to patients.

February 17th 2015

Doctors Need to Be Tech Savvy, Report Suggests

The survey, conducted by salesforce.com, showed that 71% patients want their doctor to use a mobile application to schedule appointments, share health data, and manage preventive care; 60% patients reported an interest in using telehealth in place of in-person visits.

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