Oncology

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Melanoma & Skin Cancer Awareness Month | Image credit: Waseem Ali Khan - stock.adobe.com

5 Things You Should Know About Skin Cancer

By Pearl Steinzor

May 2nd 2025

As skin cancer rates continue to rise, here are 5 key facts every health care professional should know to improve prevention, early detection, and patient outcomes.

stethoscopewithcompass | Image Credit: © Talaj-stock.adobe.com

Patient Navigation Is Nonnegotiable in Cancer Care

By Maggie L. Shaw

May 1st 2025

Liver cancer - Sebastian Kaulitzki - stock.adobe.com.jpg

Elevated HLA-G Seen in HCC Driven by Viral Infections, Fatty Liver

By AJMC Contributor

May 1st 2025

Doctor carrying documentation for patient care | image credit: Kanisorn - stock.adobe.com.jpeg

NCODA Outlines New Patient-Centered Oncology Distribution Models

By Pearl Steinzor

May 1st 2025

The thinking around which patients are eligible for liver transplants needs to evolve, the authors noted, as the criteria used to evaluate fitness for transplant were proposed nearly three decades ago. | Image credit: Peakstock - stock.adobe.com

New Developments Warrant Rethinking HCC Transplant Criteria

By Jared Kaltwasser

April 29th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

Dr Veena Shankaran Encourages Patient-Physician Communication of Care Costs

August 20th 2015

Dr Veena Shankaran Encourages Patient-Physician Communication of Care Costs

There are many cost-related pieces in the grand picture of care that are devastating to families and patients, including copayments, hospital visit bills, transportation fees, and drug prices.

August 20th 2015

Phase 2 Basket Trial Results Claim Success in BRaf V600-Mutated Cancers

Surabhi Dangi-Garimella, PhD

Conducted by researchers at the Memorial Sloan Kettering Cancer Center, phase 2 results from a basket trial evaluated the efficacy of vemurafenib on nonmelanoma BRaf V600-mutated cancers in 122 patients across 23 global centers.

August 18th 2015

Pilot of Decision Support to Individualize Colorectal Cancer Screening Recommendations

Amy R. Schwartz, MD Forrest L. Levin, MS Joseph A. O'Neil, Jr, BS R. Scott Braithwaite, MD, MSc

Colorectal cancer screening involves balancing immediate harms with longer-term benefits; electronic medical record decision support may facilitate personalized benefit/harm assessment.

August 16th 2015

The Evolving Treatment Landscape and Innovative Payment Models in Oncology: An Expert Summit

This supplement summarizes proceedings from the AJMC Oncology Stakeholders Summit, Spring 2015 series, at which experts gathered to discuss the evolving treatment landscape in oncology and the development of innovative payment models to help reduce the cost of care without sacrificing quality of care.

August 16th 2015

Special Issue Looks at What's Ahead in Precision Medicine

New resources are being directed toward precision medicine, particularly in cancer care. With that in mind, Evidence-Based Oncology, a publication of The American Journal of Managed Care, devotes its current issue to articles and commentaries on this growing field.

August 14th 2015

Chemoprevention With Oral Contraceptives Could Be a Reality

Surabhi Dangi-Garimella, PhD

Evidence provided by a study published in The Lancet Oncology affirms that oral contraceptives provide long-term protection against endometrial cancer.

August 14th 2015

Gefitinib Approved as Frontline in EGFR-Positive NSCLC

Surabhi Dangi-Garimella, PhD

August 14th 2015

Need for Palliative Care for Improved Performance at the End of Life

Surabhi Dangi-Garimella, PhD

An article published in JAMA Oncology underscores the need for efforts to improve quality of life for cancer patients.

August 14th 2015

CHAARTED Study: Conceptual Shift in Early Prostate Cancer Treatment

Surabhi Dangi-Garimella, PhD

Analysis of results from the CHAARTED trial, published in the New England Journal of Medicine, has found that 6 cycles of chemotherapy (docetaxel) before androgen-deprivation therapy early in the treatment of metastatic prostate cancer significantly improved overall survival than treatment with ADT alone.

August 14th 2015

Sonidegib Approved for Basal Cell Carcinoma

Surabhi Dangi-Garimella, PhD

August 14th 2015

JAMA Oncology Study Validates Patient-Reported Outcomes

Surabhi Dangi-Garimella, PhD

A multicollaborative study conducted for the National Cancer Institute has resulted in a tool called the Common Terminology Criteria for Adverse Events (PRO-CTCAE). PRO-CTCAE can help integrate the patient perspective into adverse event reporting.

August 13th 2015

The Diagnosis for Diagnostics: Changes to Medicare Payment and Coverage of Clinical Laboratory Tests

Adam Borden, MHA Danielle Showalter, MPH Geoffrey Storchan, PhD Kathleen Hughes, MBA

The basis for determining Medicare payment rates for clinical diagnostic laboratory tests is changing. These changes will be important for all payers and providers to follow for future reimbursement and contract negotiations.

August 13th 2015

No Solution in Sight Yet With the Federal 340B Program, Say Stakeholders

Surabhi Dangi-Garimella, PhD

A panel of healthcare experts invited by The American Journal of Managed Care participated in the Oncology Stakeholders Summit, Spring 2015 Peer Exchange, to discuss 340B and other issues in oncology care.

August 13th 2015

Choosing Well in Older Breast Cancer Patients: Retrospective Study Provides Leads

Surabhi Dangi-Garimella, PhD

A study published in the Journal of the American Geriatrics Society found that older women with breast cancer have a poor response to chemotherapy, while older patients with advanced colon cancer (both men and women) did well.

August 12th 2015

The Need to Eliminate Barriers to Personalized Medicine

Alan Balch, PhD

Precision medicine will perhaps establish some of the most important biomedical innovations of our generation. However, for that future to become a reality, we have to create an access and reimbursement environment that is conducive to precision care.

August 12th 2015

Myriad's New CEO Discusses Promise, Challenges of Changing Times in Genetic Testing

Mary K. Caffrey

Evidence-Based Oncology spoke with Mark Capone about the challenges and opportunities in molecular diagnostics, and what's ahead at Myriad Genetics.

August 12th 2015

The Vision of an Effective and Equitable Future for Personalized Medicine

Joseph Alvarnas, MD

In his editorial piece, Joseph Alvarnas, MD, narrates the importance of precision medicine in oncology care.

August 12th 2015

Need for Consistency in Radiation Treatment Costs Among Medicare Enrollees

Surabhi Dangi-Garimella, PhD

Research published in the Journal of Oncology Practice found that factors unrelated to the individual patient accounted for the majority of variation in the cost of radiation therapy for breast, prostate, and lung cancer patients.

August 11th 2015

Risk Stratification Could Improve Precision in Colon Cancer Screening

Surabhi Dangi-Garimella, PhD

A novel risk-stratification index can help avoid unnecessary colonoscopies in individuals at low-risk for developing colorectal cancer.

August 10th 2015

Noninvasive Technique Could Allow Earlier Intervention and Improve Outcomes in Pediatric Medulloblastoma

Surabhi Dangi-Garimella, PhD

A collaborative research study has discovered the effective use of magnetic resonance spectroscopy in the noninvasive diagnosis and molecular characterization of brain tumors in children.

August 10th 2015

Blinatumomab Wins CMS Favor Following Reevaluation

An immunotherapy developed by Amgen and approved by the FDA for the treatment of acute lymhoblastic leukemia in December 2014 has now received coverage assurance from Medicare, following an initial rejection.

August 10th 2015

Personalized Medicine: On the Brink of Revolutionizing Cancer Care

Sean Khozin, MD, MPH Gideon Blumenthal, MD

With unprecedented activity in the area of precision medicine, with the successful development of several targeted therapies, the FDA has been in the forefront of efforts to ensure timely access to, and the safe and effective use of, these therapies.

August 10th 2015

Equalize Payment Across Site of Service

Barry Brooks, MD

For many US community cancer centers, keeping the doors open has often meant making the difficult decision to consolidate with hospitals and large hospital systems. Site neutrality is a critical step in the journey toward better healthcare for all Americans and a healthy future for Medicare.

August 7th 2015

Alternative Payment Models: Paving the Way or Building a Wall for Personalized Medicine?

Amy M. Miller, PhD Andrew J. Shin, JD, MPH

As personalized medicine rapidly becomes an effective tool for combating cancer, payers are exploring new, value-based payment paradigms. These trends will soon intersect, and depending on how they are structured, the new payment models could accelerate or stifle personalized medicine's progress.

August 6th 2015

CHAARTED Study: Conceptual Shift in Early Prostate Cancer Treatment

Surabhi Dangi-Garimella, PhD

Results from the CHAARTED trial have found that 6 cycles of chemotherapy combined with ADT early in the treatment of metastatic prostate cancer significantly improved overall survival than with ADT alone.

August 5th 2015

Chemoprevention With Oral Contraceptives Could Be a Reality

Surabhi Dangi-Garimella, PhD

A retrospective study in The Lancet Oncology has identified a strong correlation between reduced risk of endometrial cancer and oral contraceptive agents.

August 5th 2015

Balancing Innovation With Cost in Diagnostic Testing

Gnanamba Varuni Kondagunta, MD

As clinical targets in more common malignancies emerge, testing and treatment options will increase. Balancing these choices with the high costs of new technology will be the challenge to ensure value in oncology care.

August 5th 2015

Next-Generation Sequencing: Are We There Yet?

Surabhi Dangi-Garimella, PhD

While scientists agree that NGS is the way of the future, payers are as yet apprehensive on the value afforded by the tests to clinical decisions.

August 4th 2015

Precision Oncology: Are Payers on the Right Pathway?

Jerry Conway Mark Oldroyd, JD

In oncology, the shift from a "companion diagnostic" to a "companion therapeutic" paradigm is in high gear. While the noise and confusion is leading many payers to avoid coverage, they can benefit by proactively taking steps to integrate precision oncology to better manage quality, access, and cost of cancer care.

August 4th 2015

Proteomic Analysis Yields Urine Test for Early Diagnosis of Pancreatic Cancer

Surabhi Dangi-Garimella, PhD

A research team at the Barts Cancer Institute in London has identified a 3-protein molecular signature in pancreatic cancer patients.

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