Oncology

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At 3 months, hospitalizations among patients enrolled in RSM were 19% lower vs historical controls. | Image Credit: Nuttapong punna - stock.adobe.com

Remote Symptom Monitoring Linked to Reduced Hospitalization Risk for Patients With Cancer

By Rose McNulty

May 14th 2025

Remote symptom monitoring in cancer care reduces hospitalizations, enhances value-based care, and supports diverse patient populations, according to new findings.

Offline data augmentation can significantly enhance deep learning techniques, improving classification performance compared to models trained solely on original clinician skin images. | Image Credit: Alexander - stock.adobe.com

Optimized Deep Learning Model Classifies Smartphone Images of Malignant Skin Lesions

By AJMC Contributor

May 12th 2025

With inconclusive treatment guidance and varying findings from clinical trials, the prognosis of transformed SCLC remains poor. | Image credit: Crystal Light - stock.adobe.com

Whole Exome Sequencing Identifies Distinct Profile of Transformed SCLC

By AJMC Contributor

May 12th 2025

The report suggests a TBS cutoff value of 3 will serve as a meaningful prognostic tool in HCC, but differences in patient populations and imaging techniques may affect the value of that cutoff, the authors noted. | Image credit: Jo Panuwat D - stock.adobe.com

HCC Tumor Burden Score Predicts Long-Term Outcomes Following MWA

By Jared Kaltwasser

May 7th 2025

Doctor showing lung x ray | Image credit: didesign – stock.adobe.com

Tarlatamab Safety Varies Between Clinical and Real-World SCLC Trials

By Hayden E. Klein

May 6th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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April 7th 2015

Cheaper and More Efficient Alternative to PSA Being Developed

A test that uses gold nanoparticles to detect early-stage prostate cancer costs less than $1, returns results in minutes and is more accurate than standard PSA screening, pilot studies show.

April 6th 2015

Novel Treatment Could Reduce Adverse Effects of Anticancer Agents

By combining, in a liposome, magnetic nanoparticles and photosensitizers that are simultaneously and remotely activated by a magnetic field and light, scientists obtained total tumor regression in mice.

April 6th 2015

CTCs and LDH: Surrogates for Survival in Advanced Prostate Cancer

The trial, whose results were published in the Journal of Clinical Oncology, found that circulating tumor cells and lactose dehydrogenase are ideal surrogates to predict overall survival in patients with advanced prostate cancer.

April 5th 2015

Personalized Cancer Vaccines Used to Treat 3 Patients

One day, cancer treatment regimens might include vaccines specially tailored to each patient. In a small preliminary study published in Science, researchers report successful use of these vaccines in 3 patients.

April 2nd 2015

Improving Quality of Life in Breast Cancer Beyond Pain Management

Researchers at Dartmouth's Norris Cotton Cancer Center designed rehabilitation intervention to help women with breast cancer find ways to accelerate recovery and engage in health-promoting activities.

April 2nd 2015

Payers and Providers Experiment With Oncology Payment Models

With a focus on improving quality while maintaining the cost of care, providers and payers are evaluating various payment models that could improve patient outcomes using evidence-based treatment at lower costs to the healthcare system.

April 2nd 2015

Next Gen Sequencing: ASCO Supports FDA Initiative

While supporting the FDA's standards-based regulatory efforts to explore next generation sequencing tests as diagnostic tools, the American Society of Clinical Oncology warned against misinterpretation or over-interpretation of test results.

April 1st 2015

CTCs as First-Line to Screen for Lung Cancer?

Research published by a team of Italian scientists in the Journal of the National Institute of Cancer shows that a 13-gene panel blood test for microRNAs could be a cost-effective screening tool for lung cancer, compared with low-dose CT, which is expensive.

April 1st 2015

Merck to Test Keytruda With an HDAC Inhibitor

With an aim to grab band-width in the shared PD-1 space, Merck has partnered with Syntax to conduct combination studies of Keytruda with Entinostat in melanoma and lung cancer patients.

April 1st 2015

Report Suggests Steady Improvements in Cancer Survival

The annual report was published in the March 30 issue of the Journal of the National Cancer Institute. The report was co-authored by experts from the North American Association of Central Cancer Registries, the American Cancer Society, CDC, and the National Cancer Institute.

April 1st 2015

Whose Data Is It Anyway?

Knowledge is power, as was the case with a doctoral student at MIT whose keen interest in his own medical data resulted in the diagnosis and excision of a brain tumor. But are all health systems ready to share patients' data with them?

March 31st 2015

Amgen Fails to Block Sandoz' Neupogen Biosimilar, Again

The battle is being closely watched for signs that brand-name drug makers may be able to delay the introduction of biosimilars, which are cheaper versions of brand-name biologics.

March 31st 2015

Cost Differential by Site of Service for Cancer Patients Receiving Chemotherapy

Jad Hayes, MS, ASA, MAAA J. Russell Hoverman, MD, PhD Matthew E. Brow, BA Dana C. Dilbeck, BA Diana K. Verrilli, MS Jody Garey, PharmD Janet L. Espirito, PharmD Jorge Cardona, BS Roy Beveridge, MD

The cost of care for patients receiving chemotherapy in community oncology clinics is lower than for comparable patients receiving chemotherapy in the hospital outpatient setting.

March 31st 2015

Hospitals Prefer In-House, Custom-Built Health Apps

Hospitals like Boston Children's and Penn Medicine think they are better off building in-house apps that are custom-made for their workflow, rather than risk buying those available in the market, which may not necessarily be a perfect fit.

March 31st 2015

Avoiding Unnecessary Breast Biopsies in Adolescents

An excisional biopsy, which is common in case a breast lump is detected, involves an incision along the contour of the breast and removeing the lump. However, this procedure can result in pain, scarring and breast deformity.

March 31st 2015

Low Tumor Metabolic Activity Could Predict Survival in Stage I NSCLC

Low pre-surgery uptake of a labeled glucose analogue, a marker of metabolic activity, in the primary tumor of patients with stage I non-small cell lung cancer is associated with increased overall survival and a longer time before tumor recurrence, a study shows. Patients with high labeled glucose uptake may benefit from additional therapy following surgery.

March 30th 2015

Studies Evaluate Treatments in Advanced Ovarian Cancer

Studies presented at the annual meting of the Society of Gynecologic Oncology, in Chicago, evaluated the efficacy of an experimental vaccine and an angiogenesis inhibitor in preventing the recurrence of ovarian cancer.

March 30th 2015

QALY May Stifle Patient Access to Innovative Cancer Drugs

A new study published by the IMS Institute for Healthcare Informatics finds that reimbursement approaches based on cost-per-quality-adjusted-life-year measures rather than drug effectiveness may limit access to innovative cancer treatments.

March 30th 2015

Palliative Care Improves Survival in Advanced Cancer, Studies Report

Two studies, published last week in Journal of Clinical Oncology, report improved survival as well as reduced caregiver burden following early initiation of palliative care in advanced cancer patients.

March 26th 2015

Creating a Global Cancer Resource

The Global Cancer Project Map is an interactive online database that allows users to search for cancer experts and research projects by country and by cancer type, and then to initiate contact with project principal investigators and program directors.

March 26th 2015

Survey Identifies Gaps in Communication and Decision Tools in Breast Cancer Survivors

The study, published in The Journal of Community and Supportive Oncology, discovered cancer survivors perceive gaps in their care with respect to reviewing information, asking questions, obtaining answers, and making decisions.

March 25th 2015

Nivolumab Effective in Peviously Treated RCC Patients

The authors however cautioned that we still lack an understanding of biomarker-driven patient selection for PD-1 and PD-L1 agent. Adequate knowledge of the mechanism of action of these immuno-oncology agents could help optimize therapy, they add.

March 25th 2015

Telehealth Palliative Care Model Reports Benefits in Cancer Patients

The ENABLE trial, conducted in rural regions of Vermont and New Hampshire, reports a positive impact on the 1-year survival of advanced cancer patients. A parallel study, ENABLE III, reported benefits to caregivers following early introduction of palliative care in these advanced cancer patients.

March 25th 2015

Melanoma Trial Halted Early; Keytruda Betters Yervoy

Currently, Keytruda is approved for patients with advanced melanoma previously treated with Yervoy and, in some patients, another type of drug as well. That second- and third-line status limits the number of patients eligible for the drug.

March 25th 2015

Driving Precision Medicine With Exceptional Responders

The NCI wants to encourage clinical trial investigators to review data from their completed clinical trials and treating oncologists to look back in their patient records to identify potential cases of exceptional responses and submit them for consideration in the initiative.

March 25th 2015

Diabetes Raises Risk of Developing Advanced Stage Breast Cancer, Study Finds

Diabetes is associated with more advanced stage breast cancer, according to a new study that confirms a strong link between diabetes and later stage breast cancer at diagnosis.

March 24th 2015

The FDA Has It Right With Drug Approvals

While keeping pace with the 2014 rate, the FDA is steaming ahead with approvals for a several breakthrough molecules. Everyone is not happy though, especially the payers who are looking at the $100,000 price tag on some of the specialty medications.

March 24th 2015

Provenge On Its Way to Gain Approval in Germany

Dendreon's prostate cancer immunotherapy Provenge is now being backed by IQWiG just months after the German health technology assessor was poised to reject the treatment.

March 24th 2015

Need Better Regulation for Next Gen Sequencing Tests, AMP Urges the FDA

The Association for Molecular Pathology has provided comments to the FDA, urging increased regulation of next generation sequencing diagnostic tests to ensure consistent and proper performance of the tests.

March 24th 2015

Race a Risk Factor for Cancer Mortality, Study Shows

Published in the Journal of the National Cancer Institute, the study found that most Asian subgroups were less likely to die from cancer than non-Hispanic white patients.

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