Oncology

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The investigators found that tumor mutational burden and PD-L1 expression, which have traditionally been used as indicators of immunotherapy efficacy, had little predictive value for survival in this cohort. | Image credit: Dragana Gordic - stock.adobe.com

Predictive Model Forecasts Advanced NSCLC Outcomes

By Jared Kaltwasser

August 14th 2025

The newly developed model has an area under the curve of 0.807 for predicting progression-free survival.

Dordaviprone is indicated for recurrent H3 K27M-mutant diffuse midline glioma, an ultra-rare, aggressive brain tumor primarily affecting children. | Image credit: wladimir1804 - stock.adobe.com

FDA Approves Dordaviprone as First and Only Treatment for Aggressive Form of Glioma

By Rose McNulty

August 6th 2025

Gen Li, PhD, MBA, president and founder of Phesi

Real-World Data, Digital Patient Profiles Are Revolutionizing Trial Design, Patient Recruitment: Gen Li, PhD, MBA

By Pearl Steinzor
Gen Li, PhD, MBA

August 4th 2025

Value-based care. | Image Credit: irissca - stock.adobe.com

Legal Navigation Services Key to Addressing Disparities in Cancer Care

By Cameron Santoro

July 31st 2025

Radiotherapy can work synergistically with immunotherapy by reprogramming the tumor microenvironment. | Image credit: Crystallight-stock.adobe.com

Brain Radiotherapy Plus ICIs Boost Survival in SCLC With Brain Metastases

By Jared Kaltwasser

July 30th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

Continuing Medical Education

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August 20th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology

August 20th 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

More News

November 17th 2016

ICU Admission Reduces Survival, Augments Costs Among Patients With AML

Surabhi Dangi-Garimella, PhD

A study published by researchers from the Fred Hutchinson Cancer Research Center in Seattle has found that admission to the intensive care unit reduced survival and increased the cost of care among patients undergoing treatment for acute myeloid leukemia.

November 17th 2016

Addressing the Psychosocial Needs in Older Breast Cancer Patients

Surabhi Dangi-Garimella, PhD

A study conducted in Canada to estimate the prevalence of psychotropic and opioid medication use by older women diagnosed with breast cancer found a significant increase in use, especially during the active treatment phase.

November 16th 2016

First-in-Human Trial of CRISPR-Cas9 Begins in Lung Cancer Patients

Surabhi Dangi-Garimella, PhD

A hospital in China has made history by injecting a patient with lung cancer with revolutionary, yet controversial, CRISPR-Cas9—edited T cells. The first patient was injected on October 28.

November 15th 2016

BLA for Bevacizumab Biosimilar Filed Based on Phase 3 NSCLC Data

Surabhi Dangi-Garimella, PhD

Amgen and Allergan have announced that they have submitted a Biologics License Application (BLA) for ABP 215, a biosimilar to bevacizumab (Avastin).

November 15th 2016

Combining IORT With Chemotherapy Improves Survival in Pancreatic Cancer

Surabhi Dangi-Garimella, PhD

A new study conducted at the Massachusetts General Hospital evaluated the impact of intraoperative radiotherapy (IORT), along with induction chemotherapy and chemo-radiotherapy, in patients with advanced disease, and observed hints of success.

November 14th 2016

Prospective Trial Confirms Important Role of Vitamin D in Breast Cancer

Surabhi Dangi-Garimella, PhD

A prospective trial among breast cancer patients enrolled in The Pathways Study has found that higher levels of vitamin D can lower the risk of breast cancer morbidity and mortality.

November 12th 2016

Genetic Factors Can Help Tailor Surveillance Programs for Melanoma

Surabhi Dangi-Garimella, PhD

A study conducted in Australia has concluded that a person’s inherited risk factors for melanoma should be considered when developing self-examination and surveillance programs.

November 11th 2016

The Fate of Cancer Moonshot in 2017

Surabhi Dangi-Garimella, PhD

Will Vice President Joe Biden's Cancer Moonshot initiative be able to sustain it's momentum in 2017 following the transition in government?

November 10th 2016

Nivolumab Approved in Patients With Recurrent SCCHN

AJMC Staff

The FDA today granted approval to the programmed death ligand-1 inhibitor, nivolumab (Opdivo), for treatment of patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN), following platinum-based treatment.

November 10th 2016

Medical Home Transformation and Breast Cancer Screening

Amy W. Baughman, MD, MPH Phyllis Brawarsky, MPH Tracy Onega, PhD, MS Tor D. Tosteson, ScD Qianfei Wang, MS Anna N.A. Tosteson, ScD Jennifer S. Haas, MD, MSc

Breast cancer screening may not improve in early medical home implementation.

November 10th 2016

US Cigarette Smoking Rate Sees a 5% Decrease Since 2005

Surabhi Dangi-Garimella, PhD

According to CDC’s Morbidity and Mortality Weekly Report, the cigarette smoking rate of adults in the United States has seen a significant drop during the decade from 2005 to 2015.

November 10th 2016

ASCO Upgrades Guidelines to Include Palliative Care in Standard Oncology Care

Surabhi Dangi-Garimella, PhD

The American Society of Clinical Oncology’s Ad Hoc Palliative Care Expert Panel has developed specific evidence-based recommendations for access to palliative care services for individuals with advanced cancer and for their family caregivers.

November 9th 2016

How Do Distress Tests Impact Cancer Care Providers?

Surabhi Dangi-Garimella, PhD

A study published in the Journal of the National Comprehensive Cancer Network has found that screening for distress tests improves provider confidence and awareness toward person-centered care.

November 9th 2016

Soda Taxes Pass in Four Cities, But Tobacco Votes Are Mixed

Mary Caffrey

Three of the 4 cities to pass taxes on soda are in Northern California, not far from Berkeley, which passed the nation's first soda tax in 2014.

November 8th 2016

New Digital Tool to Compare Insurance Coverage for Cancer Screening Tests

Surabhi Dangi-Garimella, PhD

The Prevent Cancer Foundation has developed a digital tool that can compare coverage of screening tests for breast, cervical, colorectal, lung, and prostate cancers across health insurance plans available in a specific state.

November 8th 2016

Humana's Roy A. Beveridge, MD, to Give Keynote at Patient-Centered Oncology Care

With value-based reimbursement now far from its infancy, the chief medical officer for Humana will forecast what’s ahead in payment reform-and how oncology connects with what is happening in primary care, hospitals, and the pharmaceutical industry. Roy A. Beveridge, MD, will open Patient-Centered Oncology Care, which will meet November 17-18, 2016, in Baltimore, Maryland.

November 7th 2016

Meta-Analysis Confirms Clinical Advantage of BRAF/MEK and PD-1 Inhibitors in Melanoma

Surabhi Dangi-Garimella, PhD

Based on a retrospective meta-analysis of clinical trial data, authors of a recent paper in JAMA Oncology concluded that BRAF/MEK and programmed death receptor-1 (PD-1) inhibitors were the most effective treatments that were relatively safe in melanoma.

November 7th 2016

Value of Second Opinion in Prostate Cancer Uncertain, Says Hopkins Study

Surabhi Dangi-Garimella, PhD

A new study by researchers at the Johns Hopkins University has found that second opinions did not change treatment choice among men diagnosed with low-risk prostate cancer.

November 4th 2016

A Diagnostic Tool for Cachexia in Cancer Patients Could Save Lives

Surabhi Dangi-Garimella, PhD

Researchers from Canada’s McGill University have developed a potential tool that can detect early signs of cachexia in cancer patients, which could impact survival.

November 4th 2016

Genetic Counseling Prerequisite Reduced Appropriate Testing, Study Finds

Surabhi Dangi-Garimella, PhD

A new study in the Journal of Oncology Practice has found that the health plan requirement of counseling by certified geneticists could have led to patient access issues in oncology.

November 3rd 2016

ASCO's Collaboration Will Expand the Reach of COME HOME for Oncology Patients

Surabhi Dangi-Garimella, PhD

The American Society of Clinical Oncology (ASCO) has announced that it is collaborating with Innovative Oncology Business Solutions, Inc, on ASCO COME HOME.

November 3rd 2016

Segment 8 - Covering the Gaps in Cancer Survivor Care

How can care providers ensure cancer survivors continue to receive adequate follow-up care post treatment?

November 3rd 2016

Segment 7 - Successful Discussions on Advance Care Planning and EOL

How can discussions on advance care planning and end-of-life care be successfully broached with patients and their family members?

November 3rd 2016

Segment 6 - Reimbursing Value-Based Oncology Care

Panelists discussed how patient-centered care can be valuated in the changing healthcare climate.

November 3rd 2016

Segment 5 - An Ideal Patient Portal

Is there anything like an ideal patient portal that can cater to a broad range of patients? According to Rebekkah Schear, MIA, what patient portals lack is a holistic approach toward the patient.

November 3rd 2016

Segment 4 - Overcoming Barriers With Data Exchange

How can we create more standardized health information platforms that can easily exchange patient information?

November 3rd 2016

Segment 3 - Challenges With Oncology Care Navigation

Cancer is a complex disease to treat an patients can be overwhelmed by the number of care providers that they have to consult with. In this scenario, care navigators can provide significant support to patients and their family members.

November 3rd 2016

Segment 2 - Documenting the Treatment Plan

Panelists discuss the need for documenting a treatment plan early in patient care.

November 3rd 2016

Segment 1 - Patient-Centered Care and Shared Decisions in Oncology

Joseph Alvarnas, MD, editor-in-chief of Evidence-Based-OncologyTM spoke with Rebekkah Schear, MIA, and Michael Kolodziej, MD, to discuss the progress and challenges in oncology care.

November 2nd 2016

Dr Andrew L. Pecora Outlines Issues Oncologists Have With Value Frameworks

Oncologists are aware of the various value frameworks that have popped up recently, but they are still in the first phase and many oncologists have issues with the frameworks, said Andrew L. Pecora, MD, FACP, CPE, chief innovation officer professor and vice president of cancer services at the John Theurer Cancer Center.

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