Oncology

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Patients with SCLC in the tarlatamab group had significantly longer overall survival, with a median of 13.6 months vs 8.3 months in the chemotherapy group. | Image credit: mi_viri - stock.adobe.com
Tarlatamab Improves SCLC Outcomes After Platinum Chemotherapy

June 19th 2025

Median overall survival was 5 months longer in patients with small cell lung cancer (SCLC) who received tarlatamab instead of chemotherapy after progression following platinum-based chemotherapy.

The data presented at ASCO reflect patients seen during 2 community health fairs designed to reach underserved populations in Georgia. | Image credit: NIKCOA - stock.adobe.com
Teledermatology Shows Promise to Reduce Disparities in Skin Cancer Screening

June 18th 2025

Patients in the cemiplimab group had superior disease-free survival vs placebo. | Image credit: Medical Works - stock.adobe.com
Cemiplimab Improves Disease-Free Survival in High-Risk, Advanced CSCC

June 13th 2025

The approval covers use of pembrolizumab as a single agent in the neoadjuvant setting, followed by adjuvant treatment with pembrolizumab in combination with radiotherapy with or without cisplatin after surgery, and then continued as a single agent. | Image credit: wladimir1804-stock.adobe.com
FDA Approves Perioperative Pembrolizumab in Resectable HNSCC

June 13th 2025

FDA approval-Olivier Le Moal-stock.adobe.com.jpeg
Mitomycin Intravesical Solution Gains FDA Approval for Recurrent Low-Grade NMIBC

June 12th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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November 30th 2017

African Americans Are More Likely to Have MM, but Are Underrepresented in Research

Kelly Davio
While African Americans are 3 times more likely than Caucasians to be diagnosed with multiple myeloma (MM)—and twice as likely to die of the disease—they are underrepresented in MM disease research.
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November 28th 2017

Significant Amount of Cancer Cases Attributable to Potentially Modifiable Risk Factors

Jaime Rosenberg
A study published in CA: A Cancer Journal for Clinicians found that 42% of all incident cancer cases in US adults age 30 years or older in 2014 were attributable to potentially modifiable exposures. Exposures included smoking, alcohol intake, physical inactivity, and low fiber intake.
Ovarian Cancer: Coverage of PARP Inhibitors
November 28th 2017

Ovarian Cancer: Coverage of PARP Inhibitors

Consulting With Gynecologic Oncologists for Input
November 28th 2017

Consulting With Gynecologic Oncologists for Input

Guidance for Payer Decisions in Ovarian Cancer
November 28th 2017

Guidance for Payer Decisions in Ovarian Cancer

Management Challenges in Ovarian Cancer
November 28th 2017

Management Challenges in Ovarian Cancer

Patient Selection and PARP Inhibitors in Ovarian Cancer
November 28th 2017

Patient Selection and PARP Inhibitors in Ovarian Cancer

Predictive Markers in Ovarian Cancer
November 28th 2017

Predictive Markers in Ovarian Cancer

Ovarian Cancer: Practical Considerations in Maintenance
November 28th 2017

Ovarian Cancer: Practical Considerations in Maintenance

Efficacy and Safety of Rucaparib: A Focus on ARIEL3
November 28th 2017

Efficacy and Safety of Rucaparib: A Focus on ARIEL3

Efficacy and Safety of Olaparib and Niraparib in Switch Maintenance
November 28th 2017

Efficacy and Safety of Olaparib and Niraparib in Switch Maintenance

Delaying Recurrence in Ovarian Cancer
November 28th 2017

Delaying Recurrence in Ovarian Cancer

Role of PARP Inhibition in Ovarian Cancer
November 28th 2017

Role of PARP Inhibition in Ovarian Cancer

Expertise on the Ovarian Cancer Healthcare Team
November 28th 2017

Expertise on the Ovarian Cancer Healthcare Team

Understanding Ovarian Cancer
November 28th 2017

Understanding Ovarian Cancer

Substantial Proportion of Patients Diagnosed With Incident Cancer Have Survived a Prior Cancer
November 28th 2017

Substantial Proportion of Patients Diagnosed With Incident Cancer Have Survived a Prior Cancer

Jaime Rosenberg
A study published in JAMA Oncology found that a significant number of patients newly diagnosed with cancer have had a prior cancer. The prevalence differed among age group and incident cancer type.
Podcast: This Week in Managed Care—CMS Addresses Drug Costs, and Other Health News
November 25th 2017

Podcast: This Week in Managed Care—CMS Addresses Drug Costs, and Other Health News

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.
This Week in Managed Care: November 24, 2017
November 24th 2017

This Week in Managed Care: November 24, 2017

This week, the top managed care stories included a new rule from CMS to address drug costs for seniors; a campaign to get payers to fund the artificial pancreas is working; and a new survey identifies how Americans prefer to treat pain.
Roche Sues Pfizer to Block Its Biosimilar Referencing Herceptin
November 23rd 2017

Roche Sues Pfizer to Block Its Biosimilar Referencing Herceptin

Jaime Rosenberg
Roche is suing Pfizer to block the company from selling a biosimilar referencing its breast-cancer drug Herceptin in the United States, claiming that the biosimilar infringes on 40 of its patents.
Chemotherapy, Radiation Therapy Recommended First for Certain Prostate Cancers, Lymphomas
November 22nd 2017

Chemotherapy, Radiation Therapy Recommended First for Certain Prostate Cancers, Lymphomas

Laura Joszt, MA
Chemotherapy and radiation therapy should be the first line of treatment for certain prostate cancers and lymphomas with a major genetic weakness, according to researchers at the University of Virginia School of Medicine.
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November 21st 2017

Analysis Identifies Attributes That Likely Contribute to High-Value Oncology Care

Jaime Rosenberg
An analysis using mixed quantitative and qualitative methods, as well as site visits to 7 US oncology practices, identified 13 attributes within 5 themes that potentially contribute to high-quality care at a relatively low total cost.
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November 18th 2017

Navigators Offer Touch Points on Patients' Cancer Journey

Mary Caffrey
The evolution of the navigator role has been an important development in cancer care, according to panelists who offered various perspectives on helping patients along the cancer journey.
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November 18th 2017

NQF and CAPC Team Up to Set Quality Standards for Community-Based Serious Illness Care

Jaime Rosenberg
With the growing shift to community-based and patient-centered care, the National Quality Forum (NQF) and the Center to Advance Palliative Care (CAPC) have launched initiatives to ensure that patients with serious illness receive safe, effective, and high-quality care. At the same time, professionals in the healthcare industry are highlighting the importance of integrating this type of care into the oncology practice.
ASCO's TAPUR Study Expands to Enroll Patients Receiving Immunotherapy
November 17th 2017

ASCO's TAPUR Study Expands to Enroll Patients Receiving Immunotherapy

AJMC Staff
With an expansion that includes immunotherapy combination treatments, the American Society of Clinical Oncology (ASCO)’s Targeted Agent and Profiling Utilization Registry (TAPUR) Study has now grown to 500 participants and 16 therapies.
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November 17th 2017

Oncologists Can Save Oncology If They Take Ownership of Costs, Kolodziej Says

Mary Caffrey
High chemotherapy costs are only one reason for the rising cost of cancer care. End-of-life care and hospitalizations are within an oncologist's control and must be better managed given new reimbursement structures.
Study Finds Oncology Care Is Cheaper in Community Settings Than Hospital-Based Practices
November 17th 2017

Study Finds Oncology Care Is Cheaper in Community Settings Than Hospital-Based Practices

Jaime Rosenberg
Authors of the study found that the mean total, chemotherapy, and physician costs were all lower in community settings compared with hospital-based settings for patients with breast, lung, and colorectal cancer. There were also fewer emergency department visits both 3 and 10 days following treatment.
FDA Action on MSK Tumor Profiling Assay Breaks Ground on Multiple Fronts
November 17th 2017

FDA Action on MSK Tumor Profiling Assay Breaks Ground on Multiple Fronts

Mary Caffrey
FDA on Thursday authorized a faster approval path for a next-generation sequencing assay developed at Memorial Sloan Kettering Cancer Center (MSK) that represents both a scientific and regulatory breakthrough at the agency.
Predicting Which Patients Will Benefit From Immunotherapy
November 16th 2017

Predicting Which Patients Will Benefit From Immunotherapy

AJMC Staff
A mathematical model may help providers better understand which patients will benefit from certain immunotherapy.
Hematological Toxicities and Febrile Neutropenia Resulting From CDK 4/6 Inhibitors
November 15th 2017

Hematological Toxicities and Febrile Neutropenia Resulting From CDK 4/6 Inhibitors

AJMC Staff
Cyclin-dependent kinase 4/6 inhibitors may have proven benefits for treating metastatic breast cancer, but the therapies are associated with hematological toxicities and febrile neutropenia.
Dr Amy Abernethy on Improving Patient Access to Oncology Clinical Trials
November 14th 2017

Dr Amy Abernethy on Improving Patient Access to Oncology Clinical Trials

As oncology moves toward more deep diagnostic testing and as standard of care continues to quickly evolve, technology advancements are necessary to continue to improve patient access to clinical trials, explained Amy Abernethy, MD, PhD, the chief medical officer, chief scientific officer, and senior vice president of oncology at Flatiron Health.
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