Oncology

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Patients in the cemiplimab group had superior disease-free survival vs placebo. | Image credit: Medical Works - stock.adobe.com
Cemiplimab Improves Disease-Free Survival in High-Risk, Advanced CSCC

June 13th 2025

Cemiplimab improved disease-free survival in patients with high-risk cutaneous squamous cell carcinoma (CSCC) and performed well in patients with advanced CSCC in the real-world setting.

The approval covers use of pembrolizumab as a single agent in the neoadjuvant setting, followed by adjuvant treatment with pembrolizumab in combination with radiotherapy with or without cisplatin after surgery, and then continued as a single agent. | Image credit: wladimir1804-stock.adobe.com
FDA Approves Perioperative Pembrolizumab in Resectable HNSCC

June 13th 2025

FDA approval-Olivier Le Moal-stock.adobe.com.jpeg
Mitomycin Intravesical Solution Gains FDA Approval for Recurrent Low-Grade NMIBC

June 12th 2025

AJMC
Utilization and Costs Among Oncologists Participating in a Private Insurance Shared Savings Model

June 11th 2025

The new report suggests the C5a-C5aRq axis might be a useful target in combination with existing therapies for cutaneous squamous cell carcinoma. | Image credit: vladimircaribb - stock.adobe.com
C5aR1 Flagged as Biomarker in Cutaneous Squamous Cell Carcinoma

June 7th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

Watch the series now!

Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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Dr Blase Polite Outlines the Decision to Move to 2-Sided Risk in the OCM
September 22nd 2019

Dr Blase Polite Outlines the Decision to Move to 2-Sided Risk in the OCM

CMS is trying to make a 2-sided risk model in the Oncology Care Model enticing for practices, but there is still a lot of math practices need to work out before making the decision, said Blase Polite, MD, associate professor of medicine and the executive director for accountable care at the University of Chicago.
Dr James Hamrick Discusses Bringing Value to Patients Through Engagement
September 21st 2019

Dr James Hamrick Discusses Bringing Value to Patients Through Engagement

The more engaged patients who have more access to their data and are more informed about what’s going on are actually going to have better outcomes most of the time, explained James Hamrick, MD, senior medical director at Flatiron Health.
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September 20th 2019

Florida Cancer Specialists & Research Institute and Humana Sign Multiyear Agreement

Florida Cancer Specialists & Research Institute and Humana Inc. have signed a new multiyear agreement that provides Humana members with in-network access to FCS’ comprehensive range of oncology services.
Too Much, Too Fast: Providers Need More Time to Operationalize Medicare's New Radiation Oncology Model
September 18th 2019

Too Much, Too Fast: Providers Need More Time to Operationalize Medicare's New Radiation Oncology Model

Jessica Walradt
CMS' new radiation oncology payment model is slated to begin on January 1, 2020, but the significant billing changes that the model requires will require more time.
Lessons From the Field: How Practices Are Succeeding Under OCM
September 18th 2019

Lessons From the Field: How Practices Are Succeeding Under OCM

Jaime Rosenberg
As rising drug costs continue to take up a larger portion of the total cost of care, practices in the Oncology Care Model find themselves in control of a shrinking portion of total costs, according to anecdotes from an academic medical center and a community-based practice during the National Comprehensive Cancer Network’s Policy Summit held September 12 in Washington, DC.
Lani Alison Discusses How the OCM Allowed for Better Integration of Palliative Care
September 15th 2019

Lani Alison Discusses How the OCM Allowed for Better Integration of Palliative Care

Lani M. Alison, BSN, MS, HCQ, PCMH, CCE, vice president of Clinical Affairs, Regional Cancer Care Associates, explains how the implementation of the Oncology Care Model (OCM) allowed practices to better integrate palliative care.
Dr Iuliana Shapira Offers Examples of How Innovation Can Transform Cancer Care Delivery
September 10th 2019

Dr Iuliana Shapira Offers Examples of How Innovation Can Transform Cancer Care Delivery

Innovation that transform cancer care delivery have to be multi-level, explained Iuliana Shapira, MD, chief medical officer, Regional Cancer Care Associates.
Mike Fazio: Practices Are Happier With PP4 Results in the OCM
September 7th 2019

Mike Fazio: Practices Are Happier With PP4 Results in the OCM

There are less surprises in the results for performance period 4 of the Oncology Care Model, and practices seem to be mostly happier with how they’ve done, said Mike Fazio, senior vice president of client services, Archway Health.
Lani Alison Outlines Questions Patients Have About Care Pathways, Treatment Guidelines
September 5th 2019

Lani Alison Outlines Questions Patients Have About Care Pathways, Treatment Guidelines

Lani M. Alison, BSN, MS, HCQ, PCMH, CCE, vice president of Clinical Affairs, Regional Cancer Care Associates, explains the questions that patients have about oncology care pathways and treatment guidelines.
Dr Shalom Kalnicki Discusses Bringing Value-Based Care to Radiation Oncology
September 1st 2019

Dr Shalom Kalnicki Discusses Bringing Value-Based Care to Radiation Oncology

The cost of radiation oncology services has typically been a small part of the Medicare and Medicaid budget, but with more patients having complex radiation treatments, it is becoming more important to have alternative payment models in the space, said Shalom Kalnicki, MD, FASTRO, FACRO, professor and chairman, radiation oncology, Montefiore Einstein Center for Cancer Care and Albert Einstein College of Medicine.
Incidences and Burden of Childhood Cancer Continue to Increase
August 31st 2019

Incidences and Burden of Childhood Cancer Continue to Increase

Alison Rodriguez
Unlike cancers common in adults, childhood cancers are unlikely to be prevented by screening.
Dr Iuliana Shapira on Managing High Costs of Immuno-Oncology Drugs in Value-Based Care
August 28th 2019

Dr Iuliana Shapira on Managing High Costs of Immuno-Oncology Drugs in Value-Based Care

Iuliana Shapira, MD, chief medical officer, Regional Cancer Care Associates (RCCA), discusses how RCCA is managing the higher costs of immuno-oncology drugs in value-based care.
Childhood Cancer Survivors Have a Heightened Risk of Heart Disease, Study Shows
August 26th 2019

Childhood Cancer Survivors Have a Heightened Risk of Heart Disease, Study Shows

Matthew Gavidia
Cancer treatment raises the risk of heart disease in childhood cancer survivors, as does diabetes and hypertension.
Dr Ginah Nightingale: Challenges of Treating Seniors With Cancer With Combination Therapies
August 25th 2019

Dr Ginah Nightingale: Challenges of Treating Seniors With Cancer With Combination Therapies

When seniors with cancer are being treated with combination therapies, providers need to keep in mind more than just the complex regimens they’re administering, said Ginah Nightingale, PharmD, associate professor of pharmacy practice at Jefferson College of Pharmacy.
Phase 1 Pancreatic Cancer Trial Identifies Effective Combination Treatment
August 23rd 2019

Phase 1 Pancreatic Cancer Trial Identifies Effective Combination Treatment

Alison Rodriguez
Finding a cure for pancreatic cancer, which is among the deadliest cancers, will require both systemic therapy and local therapy, researchers said.
Research Reveals a Lack of Racial Diversity in Clinical Trials for Cancer Drugs
August 21st 2019

Research Reveals a Lack of Racial Diversity in Clinical Trials for Cancer Drugs

Matthew Gavidia
A new study shows a lack of racial and ethnic diversity in clinical trials for cancer drugs, highlighting issues currently being addressed by the FDA.
Lani Alison: How Providers Discuss the OCM With Patients
August 18th 2019

Lani Alison: How Providers Discuss the OCM With Patients

Lani M. Alison, BSN, MS, HCQ, PCMH, CCE, vice president of Clinical Affairs, Regional Cancer Care Associates, discusses how providers discuss the Oncology Care Model (OCM) with patients and the questions they ask about it.
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August 17th 2019

AJMCtv Interviews

AJMC Staff
AJMC®TV interviews let you catch up on what’s new and important about changes in healthcare, with insights from key decision makers—from the clinician, to the health plan leader, to the regulator. When every minute in your day matters, AJMC®TV interviews keep you informed. Access the video clips at ajmc.com/interviews.
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August 17th 2019

Medical World News: Policy, Clinical, and Managed Care Updates

Alison Rodriguez Laura Joszt, MA Mary Caffrey Jaime Rosenberg
Chronic pain, obesity and cancer, multiple myeloma patterns, pancreatic cancer screening updates, and more.
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August 17th 2019

Conference Coverage: NCCN Policy Summit

Jaime Rosenberg
Coverage from the National Comprehensive Cancer Network Policy Summit held June 27, 2019, in Washington, DC.
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August 17th 2019

From the Editor-in-Chief: Within Ourselves

Joseph Alvarnas, MD
The fault, dear Brutus, is not in our stars, but in ourselves... Julius Caesar (I, ii, 140-141)
Inherited Gene Mutation Found to Raise Pancreatic Cancer Risk, Among Other Malignancies
August 15th 2019

Inherited Gene Mutation Found to Raise Pancreatic Cancer Risk, Among Other Malignancies

Matthew Gavidia
Scientists uncovered a rare, inherited gene mutation, known as RABL3, that raises the risk of pancreatic and other cancers.
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August 14th 2019

Genetic Testing Can Reduce Suffering and Save Lives

Lauren Corduck
The founder of Oneinforty discusses the importance of identifying populations at high risk of hereditary cancers, as well as the need for education, testing, and other steps to prevent cancer.
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August 14th 2019

How Data, AI Are Unlocking Secrets to Better, More Efficient Cancer Care

Allison Inserro
The Institute for Value-Based Medicine®, an initiative of The American Journal of Managed Care®, traveled to Teaneck, New Jersey, for presentations in partnership with Regional Cancer Care Associates.
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August 14th 2019

Florida Cancer Specialists, Cigna Expand Collaboration to All Cancer Types

AJMC Staff
A 28% reduction in hospital admissions leads to a broader agreement, the physicians' group and payer say.
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August 14th 2019

Jim Allison: Breakthrough Traces the Unexpected Creative Paths of a Scientist and Immuno-Oncology

Mary Caffrey
A review of the documentary on the life of James P. Allison, PhD, of The University of Texas MD Anderson Cancer Center, co-winner of the 2018 Nobel Prize in Physiology or Medicine.
How Are Oncology Practices Communicating Value-Based Care to Employers and Patients?
August 14th 2019

How Are Oncology Practices Communicating Value-Based Care to Employers and Patients?

On this episode of Managed Care Cast, we’re bringing you a portion of a panel discussion about the Oncology Care Model, held in July 2019 during a meeting of The Institute for Value-Based Medicine® (IVBM), an initiative of The American Journal of Managed Care®. At IVBM events, we gather thought leaders to share best practices across medicine, pharmacy, and management in regional locations around the country. This podcast is taken from our meeting focusing on Innovation and Quality in Oncology Care.
Study Finds Familial Risks of Second Primary Cancers for Patients With Malignant Melanoma
August 11th 2019

Study Finds Familial Risks of Second Primary Cancers for Patients With Malignant Melanoma

Alison Rodriguez
As survival rates for malignant melanoma increase, so does the likelihood that some patients will develop second primary cancers.
Podcast: This Week in Managed Care—Pancreatic Cancer Screening and Other Health News
August 11th 2019

Podcast: This Week in Managed Care—Pancreatic Cancer Screening and Other Health News

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.
OneOncology Has Begun Administering Bevacizumab, Trastuzumab Biosimilars
August 8th 2019

OneOncology Has Begun Administering Bevacizumab, Trastuzumab Biosimilars

Jaime Rosenberg
Weeks after the first 2 anticancer biosimilars entered the US market, OneOncology announced that its partner practices have already started administering the drugs.
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