Oncology

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Patients with SCLC in the tarlatamab group had significantly longer overall survival, with a median of 13.6 months vs 8.3 months in the chemotherapy group. | Image credit: mi_viri - stock.adobe.com
Tarlatamab Improves SCLC Outcomes After Platinum Chemotherapy

June 19th 2025

Median overall survival was 5 months longer in patients with small cell lung cancer (SCLC) who received tarlatamab instead of chemotherapy after progression following platinum-based chemotherapy.

The data presented at ASCO reflect patients seen during 2 community health fairs designed to reach underserved populations in Georgia. | Image credit: NIKCOA - stock.adobe.com
Teledermatology Shows Promise to Reduce Disparities in Skin Cancer Screening

June 18th 2025

Patients in the cemiplimab group had superior disease-free survival vs placebo. | Image credit: Medical Works - stock.adobe.com
Cemiplimab Improves Disease-Free Survival in High-Risk, Advanced CSCC

June 13th 2025

The approval covers use of pembrolizumab as a single agent in the neoadjuvant setting, followed by adjuvant treatment with pembrolizumab in combination with radiotherapy with or without cisplatin after surgery, and then continued as a single agent. | Image credit: wladimir1804-stock.adobe.com
FDA Approves Perioperative Pembrolizumab in Resectable HNSCC

June 13th 2025

FDA approval-Olivier Le Moal-stock.adobe.com.jpeg
Mitomycin Intravesical Solution Gains FDA Approval for Recurrent Low-Grade NMIBC

June 12th 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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December 16th 2019

Can Cancer Care Lead the Way Toward a Value-Based Future?

Keely Macmillan, MPH
A senior vice president of Archway Health discusses challenges and opportunities of the proposed Oncology Care First model.
Anthracycline, Radiation Treatment for Childhood Cancer Shown to Increase Risk of Adult Breast Cancer
December 12th 2019

Anthracycline, Radiation Treatment for Childhood Cancer Shown to Increase Risk of Adult Breast Cancer

Maggie L. Shaw
There was a 37% increase in childhood cancer survival between 1975 and 2010. With more children receiving chemotherapy and radiation to treat their diseases, leading to more survivors, awareness has grown of the belated effects of those treatments once patients reach adulthood.
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December 11th 2019

Outcome Measures for Oncology Alternative Payment Models: Practical Considerations and Recommendations

Jakub P. Hlávka, PhD Pei-Jung Lin, PhD Peter J. Neumann, ScD
This review presents a set of evidence-based outcome measures for oncology alternative payment models, drawing on evidence from existing and proposed quality measures.
Supplemental MRI of Very Dense Breast Tissue Finds Early Cancers, at Higher Risk of False Positives
December 11th 2019

Supplemental MRI of Very Dense Breast Tissue Finds Early Cancers, at Higher Risk of False Positives

Gianna Melillo
A recent study published in The New England Journal of Medicine says that women with dense breast tissue who undergo supplemental magnetic resonance imaging (MRI) tests have lower rates of interval cancers than those who receive only mammography tests, although they also had higher rates of false positive tests.
Jennifer Atkins Describes Blue Cross Blue Shield's Commitment to Innovations in Oncology
December 8th 2019

Jennifer Atkins Describes Blue Cross Blue Shield's Commitment to Innovations in Oncology

Blue Cross Blue Shield is dedicated to maintaining local relationships to ensure they can provide the best care continuum to patients, said Jennifer Atkins, MBA, vice president of Network Solutions at Blue Cross Blue Shield.
NHS Staffing Shortages Behind Delays in Cancer Diagnoses for Patients in UK
December 7th 2019

NHS Staffing Shortages Behind Delays in Cancer Diagnoses for Patients in UK

Gianna Melillo
Patients waited about 2 months longer than necessary for a cancer diagnosis in the United Kingdom, according to a study published this week.
Patients With Chemotherapy-Induced Cardiomyopathy Show Improvements in LVEF After Cardiac Resynchronization Therapy
December 4th 2019

Patients With Chemotherapy-Induced Cardiomyopathy Show Improvements in LVEF After Cardiac Resynchronization Therapy

Maggie L. Shaw
Heart issues in patients with cancer and survivors can present themselves months or years after treatment.
This Week in Managed Care: November 29, 2019
November 29th 2019

This Week in Managed Care: November 29, 2019

This week, the top managed care news included research that may hold the key to slowing progression of multiple sclerosis; Humana says it is saving billions of dollars through value-based care; the challenges of rural healthcare delivery.
Top 5 AJMC® Articles of November 2019
November 28th 2019

Top 5 AJMC® Articles of November 2019

Here are the top 5 articles for the month of November.
AJMC® Research Roundup: November 2019
November 27th 2019

AJMC® Research Roundup: November 2019

Here are 5 interesting findings from the November 2019 issue of AJMC®.
ASCO Updates Patient-Centered Oncology Payment Model
November 27th 2019

ASCO Updates Patient-Centered Oncology Payment Model

Maggie L. Shaw
After a request for additional input from oncologists, practice administrators, payer representatives, and experts in physician payment and business analysis, ASCO has issued updated guidance on PCOP. With CMS’ Oncology Care Model set to end in 2021, the current draft of ASCO’s Community-based Oncology Medical Home model would be an option to take its place.
Dr James Hamrick Offers Advice for Providers Looking to Implement Patient Engagement Programs
November 25th 2019

Dr James Hamrick Offers Advice for Providers Looking to Implement Patient Engagement Programs

The biggest advice I would give to practices and care teams trying to really engage patients more is be innovative, explained James Hamrick, MD, senior medical director at Flatiron Health.
Dr Joshua Ofman: Early Detection of Cancer Is Vital to the Progression of Oncology Care
November 22nd 2019

Dr Joshua Ofman: Early Detection of Cancer Is Vital to the Progression of Oncology Care

GRAIL has generated enormous innovations in oncology care over the past 2 decades and will continue this trend through exploring 1 of oncology’s biggest opportunities, early detection of cancer, said Joshua Ofman, MD, chief of Corporate Strategy and External Affairs at GRAIL Inc.
What We're Reading: Vaping Ban Bill; Anal Cancer Rates; Medical Bill Protections
November 20th 2019

What We're Reading: Vaping Ban Bill; Anal Cancer Rates; Medical Bill Protections

AJMC Staff
A House committee approves a bill to ban all flavored tobacco products; anal cancer rates are on the rise; the debate continues over competing healthcare measures.
Nina Chavez on Whether Biosimilars Will Offer Cost Savings in Oncology
November 16th 2019

Nina Chavez on Whether Biosimilars Will Offer Cost Savings in Oncology

Nina Chavez, MBA, FACMPE, chief operating officer, New Mexico Oncology Hematology Consultants, Ltd., discusses if she thinks biosimilars will play a role in lowering costs in coming years.
Dr James Hamrick on Challenges With Understanding, Acting on What Constitutes Value for Patients
November 13th 2019

Dr James Hamrick on Challenges With Understanding, Acting on What Constitutes Value for Patients

James Hamrick, MD, senior medical director at Flatiron Health, discusses some of the biggest challenges with trying to understand what constitutes value for patients and then turning that into actionable information.
Erich Mounce: Providing Relevant Data to Provider Practices Encourages Growth
November 12th 2019

Erich Mounce: Providing Relevant Data to Provider Practices Encourages Growth

Providing providers with relevant data on quality of care and profitability allows them to adjust their practices efficiently, said Erich Mounce, chief operating officer, OneOncology.
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November 12th 2019

Multimodality Cancer Care and Implications for Episode-Based Payments in Cancer

Suhas Gondi, BA Alexi A. Wright, MD, MPH Mary Beth Landrum, PhD Jose Zubizarreta, PhD Michael E. Chernew, PhD Nancy L. Keating, MD, MPH
Most patients receiving multimodality cancer care receive care from different practices. Therefore, episode-based payments in oncology must hold multiple providers accountable for costs and quality.
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November 12th 2019

Money, Mandate Are Keys to FDA's Drive for Use of Real-World Evidence, Gottlieb Says

Mary Caffrey
Former FDA Commissioner Scott Gottlieb, MD, who has returned to the American Enterprise Institute, left FDA in April after 2 whirlwind years that saw a record pace of approvals and policy actions that covered everything from high drug prices to teen vaping. He spoke Friday in Philadelphia at Patient-Centered Oncology Care®, the annual meeting of oncology reimbursement stakeholders held by The American Journal of Managed Care®.
Podcast: This Week in Managed Care—Life After the Oncology Care Model and Other Health News
November 10th 2019

Podcast: This Week in Managed Care—Life After the Oncology Care Model and Other Health News

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.
Tracy Bahl: Unifying Interests to Improve Oncology in a Consolidated Way Can Improve Patient Care
November 8th 2019

Tracy Bahl: Unifying Interests to Improve Oncology in a Consolidated Way Can Improve Patient Care

Consolidating unified interests for improved cancer care can enhance efficiency and quality of care for patients, said Tracy Bahl, MBA, president and chief executive officer of OneOncology.
This Week in Managed Care: November 8, 2019
November 8th 2019

This Week in Managed Care: November 8, 2019

This week, the top managed care news included CMS started planning for life after the Oncology Care Model; a judge blocked a rule requiring immigrants to have health coverage; Election Day brought news for Medicaid work rules.
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November 6th 2019

Electronic PROs a Proposed Feature of Successor Model in Oncology Care

Mary Caffrey
Oncology care groups have praised the multipayer Oncology Care Model (OCM) for transforming cancer care through greater focus on care navigation, palliative care, survivorship, and keeping patients out of the emergency department. But there are complaints that practices can be penalized for elements beyond their control—notably, the soaring cost of state-of-the-art immunotherapies that were not on the market when the OCM was conceived.
Bobby Green: Data Utilization Crucial in Choosing Methods of Effective Care
November 5th 2019

Bobby Green: Data Utilization Crucial in Choosing Methods of Effective Care

By continuing to gather data on specific genomic data and profiles, we can heighten knowledge of applied treatment information on patient conditions, said Bobby Green, MD, chief medical officer at Flatiron.
Dr Lawrence Shulman Outlines the Potential of Value-Based Care in Oncology
November 1st 2019

Dr Lawrence Shulman Outlines the Potential of Value-Based Care in Oncology

Lawrence N. Shulman, MD, director of the Center for Global Cancer Medicine at the Abramson Cancer Center, and professor of Medicine at the Hospital of the University of Pennsylvania, discusses how value-based care can advance the quality of oncology care that it isn't currently.
Bradley Prechtl Explains the Importance of Dispelling Patient Misconceptions of Clinical Trials
October 31st 2019

Bradley Prechtl Explains the Importance of Dispelling Patient Misconceptions of Clinical Trials

I think there is a lot of confusion, especially in the patient community, about clinical research., explained Bradley Prechtl, MBA, chief executive officer of Florida Cancer Specialists and the American Oncology Network.
Dr Jeremy Whalen Outlines the Development and Application of Medical Strategies for Efficient Care
October 31st 2019

Dr Jeremy Whalen Outlines the Development and Application of Medical Strategies for Efficient Care

Referencing patients as attributable examples of necessary care has assisted in developing strategies for pharmacy and medication benefits, said Jeremy Whalen, PharmD, BCOP, Specialty Clinical Program Director for Oncology at Prime Therapeutics.
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October 30th 2019

Unlocking Data Key to Value-Based Agreements With Pharma

Mary Caffrey
Proposed changes to the Stark Law that would make collaboration easier have purposely excluded pharmaceutical manufacturers, according to speakers at the Community Oncology Alliance Payer Exchange Summit.
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October 30th 2019

CMS' Innovation Leader Touts Value of Physician Feedback

Mary Caffrey
The Oncology Care Model is a leading innovation in the move from fee-for-service to value-based reimbursement in large part because CMS has made adjustments based on physician feedback, according to an agency official who addressed the Community Oncology Alliance Payer Exchange Summit.
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October 29th 2019

Moving Into the Future of Cancer Care Through OCM 2.0

Mary Caffrey
What would a successor to the Oncology Care Model (OCM) look like? Community oncologists discuss at the Payer Exchange Summit sponsored by the Community Oncology Alliance.
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