Ophthalmology

A substantial proportion of patients with inherited retinal disease could be treated with base editing, while therapeutic strategies that focus on common variants could be used to treat a large number of patients with the disease, according to study results.

Results of a case-control study show metformin use may protect against the development of age-related macular degeneration (AMD) in adults 55 years and older, and the association is dose-dependent, with the greatest benefit at low to moderate doses.

During the coronavirus disease 2019 pandemic in France, researchers found a 7-fold increase in the number of alcohol-based hand sanitizer eye exposures among children.

Results from a prospective observational study showed aqueous transforming growth factor beta and autotaxin exhibited high diagnostic performance in detecting glaucoma subtypes and could serve as promising biomarkers for glaucoma.

Swedish patients with type 2 diabetes and obesity who underwent gastric bypass surgery exhibited a reduced risk of developing new diabetic retinopathy, compared with those who did not undergo surgery.

Home confinement during the coronavirus disease 2019 pandemic was associated with a significant myopic shift among Chinese children aged 6 to 8, according to new research published in JAMA Ophthalmology.

Study results, published in JAMA Ophthalmology, showed the Home Acuity Test can be used to measure visual acuity by telephone for a wide range of outpatients with diverse conditions under the care of an ophthalmologist.

In an effort to detect sea fan neovascularization from ultra-widefield color fundus photographs from patients with sickle cell hemoglobinopathy, researchers developed an automated system with high sensitivity and specificity, which holds potential to improve screening for vision-threatening proliferative sickle cell retinopathy.

Results from a cross-sectional study show individuals with Parkinson disease exhibited decreased retinal vessel and perfusion density, as well as choroidal structural changes compared with age- and sex-matched controls.

Among children who underwent unilateral cataract removal in infancy, risk of glaucoma-related adverse events continues to increase with longer follow-up and is not associated with primary intraocular lens (IOL) implementation, according to research published in JAMA Ophthalmology.

In a year in which health care professionals were forced to alter treatment plans to adjust to an ongoing health crisis, the majority of our most popular ophthalmology stories of 2020 involved the intersection of ophthalmologic care and coronavirus disease 2019.

Verana Health, along with the FDA, the American Glaucoma Society, and American Academy of Ophthalmology, recently announced the launch of the Patient-Reported Outcomes for Minimally Invasive Glaucoma Surgery study with the first patient enrolled.

The most significant ocular symptom experienced by those suffering from coronavirus disease 2019 (COVID-19) was sore eyes, according to new research published in BMJ Open Ophthalmology.

Visual hallucinations (VH) among patients with Parkinson disease (PD) appear to be associated with thinning of the inner retina, according to research published in Scientific Reports.

Friction of surgical instruments has the greatest association with incisional Descemet membrane detachment (DMD) during cataract surgery, according to results of a case series published in JAMA Ophthalmology.

During the enactment period of recent Michigan opioid laws, a reduction in opioid prescriptions for oculoplastic and orbital procedures was observed and appeared to be sustained, according to research published in JAMA Ophthalmology.

An increase in primary rhegmatogenous retinal detachment incidence (RRD) may be associated with a simultaneous increase in myopia among citizens residing in the Netherlands, according to study results published in JAMA Ophthalmology.

Results of a retrospective case series revealed an association between blood-brain barrier disruption (BBBD)–related maculopathy and the number of BBBD treatment sessions patients underwent, suggesting a dose-dependent effect of the treatment.

By analyzing retrospective consecutive case series, researchers identified 5 clinical and radiographic variables associated with increased risk of serious ocular injury in patients with orbital fracture to aid non-ophthalmologists in triaging these patients for urgent ophthalmologic evaluation.

Among patients with glaucoma, diffuse rather than focal glaucomatous macular damage was associated with diminished facial recognition and contrast sensitivity, according to results of a cohort study published in JAMA Ophthalmology.

Findings published in BMC Ophthalmology suggest that during diagnosis and follow-up of glaucoma with high myopia, more attention ought to be focused on structure and functional defects in macular areas.

Women filling a prescription for female hormone therapy (FHT), and presumably taking FHT, are not at increased risk of retinal artery or retinal vein occlusions.

An abnormal red reflex finding most likely reflects an underlying ocular pathology in infants, but finding a normal red reflex during screening does not altogether exclude ocular disease.

Between 2003 and 2016, the United States saw a 4-fold increase in drug use–related endogenous endophthalmitis hospitalizations, contributing to a substantial health care use burden.

New data to be presented at the American Academy of Ophthalmology’s Annual Meeting highlight the efficacy of Tepezza (teprotumumab), the first and only FDA approved medicine for thyroid eye disease.